ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Increased Risk of Breakthrough Infection among Cytomegalovirus Donor Positive/Recipient Negative Kidney Transplant Recipients Receiving Lower Dose Valganciclovir Prophylaxis

    D. Stevens, J. Trofe-Clark, E. Blumberg, M. Wilck, B. Weikert, S. Goral, M. Bleicher, D. Sawinski, P. Abt, M. Levine, P. Porrett, R. Bloom

    Pharmacy, Hospital of Univ of Pennsylvania, Philadelphia; Medicine, Perelman School of Medicine, Univ of Pennsylvania, Philadelphia; Transplant Surgery, Perelman School of Medicine, Univ of Pennsylvania, Philadelphia

    Data suggests that lower dose (LD, 450mg/day for 6 months) valganciclovir prophylaxis (VGV PPX) is non-inferior to standard dose (SD, 900mg/day for 6 months) VGV…
  • 2013 American Transplant Congress

    Three-Gene Signature of Tolerance for Clinical Application in Kidney Transplant Recipients

    I. Rebollo-Mesa, P. Mobillo, E. Nova-Lamperti, S. Norris, Y. Kamra, M. Runglall, GAMBIT Consortium, Immune Tolerance Network, Indices of Tolerance Consortium, G. Lord, R. Lechler, M. Hernandez-Fuentes

    MRC Centre for Transplantation, King's College London, London, United Kingdom; NIHR BRC at GSTT, KCL and KCH, London, United Kingdom; www.GAMBITstudy.co.uk; www.immunetolerance.org; www.transplantation-tolerance.co.uk; King's Health Partners, London, United Kingdom

    Long-life immunosuppression is an important factor that contributes to shorten the long-term survival of kidney transplant recipients. Identifying patients in whom donor-specific tolerance has developed…
  • 2013 American Transplant Congress

    Expanding the Deceased Donor Pool

    D. Adey, R. Perez, M. Alnimri, A. de Mattos

    Int Med, Univ of Calif Davis, Sacramento, CA; Surgery, Univ of Calif, Davis, Sacramento, CA

    The rate of listing of candidates for kidney transplantation continues to exceed the rate of transplantation. To narrow this gap the conventional boundaries for deceased…
  • 2013 American Transplant Congress

    Intended and Unintended Consequences of Share 35

    C. Chesley, W. Parker, L. Ross, J. Thistlethwaite, Jr

    University of Chicago, Chicago, IL

    Purpose: To evaluate the impact of Share-35 implemented 9/30/05 by the United Network for Organ Sharing (UNOS) that gives pediatric patients with end stage renal…
  • 2013 American Transplant Congress

    HLA Class II Mismatch Is Associated with Higher Incidence of Antibody Mediated Rejection after Heart Transplantation

    A. Saidi, G. Snow, K. Brunisholz, E. Hammond, O. Wever-Pinzon, S. Drakos, C. Selzman, P. Revelo, R. Alharethi, D. Miller, J. Nativi-Nicolau, B. Reid, D. Budge, E. Gilbert, A. Kfoury, J. Stehlik

    UTAH Cardiac Transplant Program, Salt Lake City, UT

    Background:Whether HLA-mismatch is associated with higher rates of antibody-mediated rejection (AMR) after heart transplantation (HTx), and whether Class I and Class II antigens have a…
  • 2013 American Transplant Congress

    Low Affinity Memory CD8+ T Cells Are Potently Alloreactive Against High Affinity Antigen in a Model of T Cell Receptor Cross-Reactive Heterologous Immunity

    S. Krummey, C. Larsen, M. Ford

    Emory Transplant Center, Atlanta, GA

    T cell activation in the context of both protective immunity and alloreactivity involves contact between the T cell receptor (TCR) and antigen presented as the…
  • 2013 American Transplant Congress

    Opportunities for Expanding the Deceased Donor Pool in an Era of Outcomes-Driven Health Care

    D. Adey, R. Perez, M. Alnimri, A. De Mattos

    Internal Medicine, Univ of Calif, Davis, Sacramento, CA; Surgery, Univ of Calif, Davis, Sacramento, CA

    Background: The rate of listing of candidates for kidney transplantation continues to exceed the rate of transplantation. In an attempt to narrow this gap the…
  • 2013 American Transplant Congress

    Pediatric Size Matched Single Renal Transplantation

    M. McMellen, J. Hopping, S. Wilson, E. Wood, E. Abraham, M. Schnitzler, J. Tuttle-Newhall

    Department of Surgery, Division of Transplant Surgery, St Louis University, St Louis, MO; Department of Pediatrics, Division of Nephrology, SSM Cardinal Glennon Medical Center, St Louis, MO

    Background: Pediatric cadaveric kidneys from small donors are offered as en bloc kidneys for transplantation. Recent data supports using these en bloc kidneys in pediatric…
  • 2013 American Transplant Congress

    Post-Transplant Colonization and Infection with Voriconazole-Resistant Mould in Lung Transplant Recipients Receiving Voriconazole Prophylaxis

    J. Kim, S. Cohen, E. Allen, R. Boettger, M. Binstock, S. Arron, J. Singer, S. Hays, J. Kukreja, P. Chin-Hong

    Infectious Diseases, University of California, San Francisco; Internal Medicine, University of California, San Francisco; Biostatistics and Epidemiology, University of California, San Francisco; Clinical Pharmacology, University of California, San Francisco; Dermatology, University of California, San Francisco, CA; Pulmonary and Critical Care, University of California, San Francisco; Thoracic Surgery, University of California, San Francisco

    Background: Because invasive aspergillosis is a major complication in lung transplant recipients (LT-R), many centers employ voriconazole (VOR) prophylaxis. It is controversial whether there is…
  • 2013 American Transplant Congress

    Exploring the Role of Embryonic Liver Development Genes in HCV Induced Cirrhosis and Hepatocellular Carcinoma

    M. Behnke, M. Reimers, R. Fisher

    Virginia Commonwealth University, Richmond, VA

    Introduction: HCC shares pathways with regulators of liver development. Wound healing recapitulates early liver development (hepatoblast proliferation) while regeneration resembles late embryonic growth (hepatocyte proliferation).…
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