2013 American Transplant Congress
Impact of Pre-Transplant Donor Renal Function on Graft Survival Following Kidney Transplantation
Introduction: Improved post-transplant renal function (RF) at 6 months is associated with improved long-term graft survival (GS). We evaluated how much of the impact of…2013 American Transplant Congress
Association of HLA Amino Acid Mismatches with Kidney Allograft Failure
The effect of HLA matching on kidney allograft survival is usually analyzed based on HLA serologic specificity and does not take into account other HLA…2013 American Transplant Congress
Influence of SLCO1B1 and SLCO2B1 Polymorphisms on Tacrolimus Pharmacokinetics and Clinical Efficacy and Safety
Introduction: Tacrolimus (TAC) has a narrow therapeutic range and is associated with increased risk of nefrotoxicity after kidney transplantation. Variants in transporter genes have been…2013 American Transplant Congress
Long-Term Safety and Effectiveness of Inhibitors of the Mammalian Target of Rapamycin in De Novo Kidney Transplantation: 10 Years of a Single Center Experience
Nephrology Division, Hospital do Rim e Hipertensão, São Paulo, Brazil
Introduction: The aim of this study was to evaluate long-term safety outcomes of de novo kidney transplant recipients who received MTORi [sirolimus (SRL) or Everolimus…2013 American Transplant Congress
Pattern of Utilization and Graft Outcomes of Patients Received Kidney Transplants from Deceased Donors < 4 Years, The
Kidneys from donors < 4 years remain underutilized because of the concerns of the recipient complications (bleeding, urine leak and graft thrombosis), and poor long-term…2013 American Transplant Congress
Comparison of Protein A-Immuno-Adsorption and Conventional Plasma Exchanges for Anti-HLA Desensitization
Nephrology, Dialysis, Transplantation, University Hospital, Saint-Etienne, France
Plasma exchanges therapy is traditionally part of anti-HLA desensitization strategies used in kidney transplantation. As compared to conventional techniques of plasma exchanges (PE) (plasma-centrifugation or…2013 American Transplant Congress
“Spontaneous” Reduction in Donor Specific Allo-Antibody (DSA) after Positive Cross Match Kidney Transplantation (+XMKTx) Is Associated with Improved Histology
Introduction.In a recent study (AJT,2011;11:2405), eculizumab decreased the incidence of early antibody mediated rejection(AMR) after +XMKTx. Post-transplant plasma exchange (PE) was not routinely used thus…2013 American Transplant Congress
Effect of the Purinergic Inhibitor Oxidized-ATP in a Model of Islet Allograft Rejection
The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2Xs) sense the ATP, released during cell damage-activation, thus regulating T-cell activation. We aim to define the…2013 American Transplant Congress
CD8+TCR- Bone Marrow Facilitating Cells Induce Generation of IL-10-Producing Type 1 Regulatory T Cells In Vitro: A Critical Role for DOCK2 and Cell-Contact
We recently reported induction of high levels of chimerism and donor-specific tolerance without GVHD in mismatched related and unrelated kidney transplant recipients through administration of…2013 American Transplant Congress
Backdating Waiting Time to Date of First Maintenance Dialysis Significantly Reduces Median Time To Transplant for Kidney Transplant Candidates with Long Pre-Waitlisting Dialysis Duration
Insurance type and minority status are associated with large disparities in the duration of pre-waitlisting dialysis (PWLD) among candidates for kidney transplantation. To partially redress…
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