ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Association between Methods of Proteinuria Screening and the Metabolic Syndrome in Potential Living Kidney Donors

    V. Vidyasagar, S. Shah, M. Mohamed, B. Muth, J. Turk, A. Djamali, D. Kaufman, J. Pirsch, D. Foley, J. Mezrich, B. Astor, R. Hofmann

    Dept. of Medicine- Division of Nephrology, University of Wisconsin, Madison; Dept. of Surgery- Division of Transplantation Surgery, University of Wisconsin, Madison

    Background: Proteinuria is a major risk factor for progression in chronic kidney disease. Identification of proteinuria thus may have important implications for kidney donor prognosis…
  • 2013 American Transplant Congress

    Systematic Study of Causes of Death and Allograft Loss in Pancreas Transplantation in the Modern Era with ATG Induction and Tacrolimus Based Triple Immunosuppression

    Y. Kudva, M. Dong, A. Parsaik, W. Kremers, P. Dean, F. Cosio, M. Prieto, M. Stegall

    Endocrinology, Mayo Clinic, Rochester, MN

    Background: Improved surgical techniques, modern immunosuppressive regimens, and a better understanding of donor and recipient risk factors have led to excellent short-term graft survival after…
  • 2013 American Transplant Congress

    Development of Micro Bioscaffold as a Multiplex System To Evaluate Bioactive Molecules That Enhance Cell Function

    B. Wang, A. Jakus, A. Wu, Y. Wu, J. Zhang, R. Shah, J. Wertheim

    Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL; Institute for BioNanotechnology in Medicine and Chemistry of Life Processes Institute, Northwestern University, Chicago, IL; Chemistry of Life Processes Institute, Northwestern University, Chicago, IL, Uganda

    Introduction: This study focuses on creating two types of micro biomimetic scaffolds: natural bioscaffold derived from decellularized liver and micron-scale biodegradable polylactide scaffolds infused with…
  • 2013 American Transplant Congress

    Impaired Effector/Memory CD8+ T Cell Response Delays Acute Allograft Rejection in Older Recipients

    A. Elkhal, D. Bedi, C. Denecke, A. Jurisch, I. Kim, T. Heinbokel, H. Li, X. Yuan, X. Ge, S. Tullius

    Surgery, Brigham and Women's Hospital, Boston, MA

    Background: Over the past decade, the proportion of patients over the age of 65, both, waiting for and receiving transplants has increased dramatically. It is…
  • 2013 American Transplant Congress

    Comparison of Protein A-Immuno-Adsorption and Conventional Plasma Exchanges for Anti-HLA Desensitization

    N. Maillard, I. Masson, M. Mehdi, E. Alamartine, C. Mariat

    Nephrology, Dialysis, Transplantation, University Hospital, Saint-Etienne, France

    Plasma exchanges therapy is traditionally part of anti-HLA desensitization strategies used in kidney transplantation. As compared to conventional techniques of plasma exchanges (PE) (plasma-centrifugation or…
  • 2013 American Transplant Congress

    “Spontaneous” Reduction in Donor Specific Allo-Antibody (DSA) after Positive Cross Match Kidney Transplantation (+XMKTx) Is Associated with Improved Histology

    S. Raghavaiah, M. Gandhi, L. Cornell, W. Kremers, P. Dean, T. Taner, M. Stegall

    Transplant, Mayo Clinic, Rochester, MN; Transfusion Medicine, Mayo Clinic, Rochester, MN; Anatomic Pathology, Mayo Clinic, Rochester, MN

    Introduction.In a recent study (AJT,2011;11:2405), eculizumab decreased the incidence of early antibody mediated rejection(AMR) after +XMKTx. Post-transplant plasma exchange (PE) was not routinely used thus…
  • 2013 American Transplant Congress

    Pattern of Utilization and Graft Outcomes of Patients Received Kidney Transplants from Deceased Donors < 4 Years, The

    T. Jie, M. Porubsky, A. Rana, B. Kaplan, R. Gruessner, A. Gruessner

    Department of Surgery, University of Arizona, Tucson, AZ; Department of Medicine, University of Arizona, Tucson, AZ

    Kidneys from donors < 4 years remain underutilized because of the concerns of the recipient complications (bleeding, urine leak and graft thrombosis), and poor long-term…
  • 2013 American Transplant Congress

    Effect of the Purinergic Inhibitor Oxidized-ATP in a Model of Islet Allograft Rejection

    A. Vergani, R. Bassi, F. D'Addio, C. Fotino, S. Tezza, R. Molano, A. Soleti, P. Maffi, A. Secchi, C. Ricordi, M. Sayegh, A. Pileggi, P. Fiorina

    Boston Children's Hospital/Harvard Medical School, Boston; San Raffaele Scientific Institute, Milan, Italy; DRI, University of Miami, Miami; Medestea, Torino, Italy

    The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2Xs) sense the ATP, released during cell damage-activation, thus regulating T-cell activation. We aim to define the…
  • 2013 American Transplant Congress

    CD8+TCR- Bone Marrow Facilitating Cells Induce Generation of IL-10-Producing Type 1 Regulatory T Cells In Vitro: A Critical Role for DOCK2 and Cell-Contact

    Y. Wen, Y. Huang, M. Elliott, D. Corbin, T. Miller, Y. Fukui, S. Ildstad

    Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; Department of Immunobiology and Neuroscience, Kyushu University, Fukuoka, Japan

    We recently reported induction of high levels of chimerism and donor-specific tolerance without GVHD in mismatched related and unrelated kidney transplant recipients through administration of…
  • 2013 American Transplant Congress

    Backdating Waiting Time to Date of First Maintenance Dialysis Significantly Reduces Median Time To Transplant for Kidney Transplant Candidates with Long Pre-Waitlisting Dialysis Duration

    A. Leichtman, K. Wisniewski, V. Ashby, R. Merion, G. Danovitch

    U of Michigan, Ann Arbor; Arbor Research Collaborative for Health, Ann Arbor; U of California, Los Angeles

    Insurance type and minority status are associated with large disparities in the duration of pre-waitlisting dialysis (PWLD) among candidates for kidney transplantation. To partially redress…
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