ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Killer Immunoglobulin-Like Receptor (KIR) Mismatches and KIR-HLA-C Interactions Do Not Affect Short Term Graft Function in Kidney Transplantation

    E. Eksioglu-Demiralp, M. Elbasi, F. Ture-Ozdemir, A. Tulunay, I. Tatli-Aydin, A. Turkmen, B. Kocak

    Tissue Typing and Immunology, Istanbul Memorial Hospital, Transplantation Unit, Istanbul, Turkey; Basic Immunology, Marmara University, School of Medicine, Istanbul, Turkey; Transplantation Unit, Istanbul Memorial Hospital, Istanbul, Turkey

    Human Leucocyte Antigen (HLA) matching is an important factor in long term graft survival in kidney transplantations. Natural Killer (NK) cells with their MHC recognizing…
  • 2013 American Transplant Congress

    Increasing Resistance in Gramnegative Bacilli Causing Urinary Tract Infection (UTI) in Two Cohorts of Kidney Transplant (KT) Recipients: An Emerging Problem

    J. Origüen, F. López-Medrano, A. Pérez-Jacoiste, A. García-Reyne, N. Carrasco, M. Orellana, A. Andrés, J. Morales, J. Aguado

    Hospital 12 de Octubre, Madrid, Spain

    BackgroundUTI is the most common infection following KT. The increasing resistance in gramnegative bacilli could have an special impact on this population.MethodsTwo cohorts were followed…
  • 2013 American Transplant Congress

    Early Protocol Biopsies Can Identify Antibody-Mediated Rejection in Sensitized Patients

    P. Souza, D. Machado, A. Aguirre, D. David, E. Barbosa, F. de Paula, W. Nahas, E. David-Neto, M. Castro

    Renal Transplant Service, Hospital das Clinicas University of São Paulo, São Paulo, Brazil

    HLA sensitized patients are at risk for antibody-mediated rejection (ABMR). Our purpose was to evaluate the importance of early protocol biopsies. From Jul/2010 to Jun/2012,…
  • 2013 American Transplant Congress

    Normothermic Acellular Ex Vivo Liver Perfusion (NEVLP): Development of a New Method for the Storage, Assessment, and Repair of Marginal Liver Grafts

    M. Boehnert, J. Knaak, O. Adeyi, P. Yip, N. Selzner, G. Levy, S. Keshavjee, D. Grant, M. Selzner

    Department of Surgery, Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada; Department of Pathology, Toronto General Hospital, Toronto, ON, Canada; Department of Clinical Chemistry, Toronto General Hospital, Toronto, ON, Canada; Department of Surgery, Toronto Lung Transplant Program, Toronto General Hospital, Toronto, ON, Canada

    We compared the novel normothermic acellular ex vivo liver perfusion (NEVLP) with conventional cold static organ preservation for livers retrieved after cardiac death.Methods: Pig livers…
  • 2013 American Transplant Congress

    Pattern of Utilization and Graft Outcomes of Patients Received Kidney Transplants from Deceased Donors < 4 Years, The

    T. Jie, M. Porubsky, A. Rana, B. Kaplan, R. Gruessner, A. Gruessner

    Department of Surgery, University of Arizona, Tucson, AZ; Department of Medicine, University of Arizona, Tucson, AZ

    Kidneys from donors < 4 years remain underutilized because of the concerns of the recipient complications (bleeding, urine leak and graft thrombosis), and poor long-term…
  • 2013 American Transplant Congress

    Comparison of Protein A-Immuno-Adsorption and Conventional Plasma Exchanges for Anti-HLA Desensitization

    N. Maillard, I. Masson, M. Mehdi, E. Alamartine, C. Mariat

    Nephrology, Dialysis, Transplantation, University Hospital, Saint-Etienne, France

    Plasma exchanges therapy is traditionally part of anti-HLA desensitization strategies used in kidney transplantation. As compared to conventional techniques of plasma exchanges (PE) (plasma-centrifugation or…
  • 2013 American Transplant Congress

    “Spontaneous” Reduction in Donor Specific Allo-Antibody (DSA) after Positive Cross Match Kidney Transplantation (+XMKTx) Is Associated with Improved Histology

    S. Raghavaiah, M. Gandhi, L. Cornell, W. Kremers, P. Dean, T. Taner, M. Stegall

    Transplant, Mayo Clinic, Rochester, MN; Transfusion Medicine, Mayo Clinic, Rochester, MN; Anatomic Pathology, Mayo Clinic, Rochester, MN

    Introduction.In a recent study (AJT,2011;11:2405), eculizumab decreased the incidence of early antibody mediated rejection(AMR) after +XMKTx. Post-transplant plasma exchange (PE) was not routinely used thus…
  • 2013 American Transplant Congress

    Effect of the Purinergic Inhibitor Oxidized-ATP in a Model of Islet Allograft Rejection

    A. Vergani, R. Bassi, F. D'Addio, C. Fotino, S. Tezza, R. Molano, A. Soleti, P. Maffi, A. Secchi, C. Ricordi, M. Sayegh, A. Pileggi, P. Fiorina

    Boston Children's Hospital/Harvard Medical School, Boston; San Raffaele Scientific Institute, Milan, Italy; DRI, University of Miami, Miami; Medestea, Torino, Italy

    The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2Xs) sense the ATP, released during cell damage-activation, thus regulating T-cell activation. We aim to define the…
  • 2013 American Transplant Congress

    CD8+TCR- Bone Marrow Facilitating Cells Induce Generation of IL-10-Producing Type 1 Regulatory T Cells In Vitro: A Critical Role for DOCK2 and Cell-Contact

    Y. Wen, Y. Huang, M. Elliott, D. Corbin, T. Miller, Y. Fukui, S. Ildstad

    Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; Department of Immunobiology and Neuroscience, Kyushu University, Fukuoka, Japan

    We recently reported induction of high levels of chimerism and donor-specific tolerance without GVHD in mismatched related and unrelated kidney transplant recipients through administration of…
  • 2013 American Transplant Congress

    Backdating Waiting Time to Date of First Maintenance Dialysis Significantly Reduces Median Time To Transplant for Kidney Transplant Candidates with Long Pre-Waitlisting Dialysis Duration

    A. Leichtman, K. Wisniewski, V. Ashby, R. Merion, G. Danovitch

    U of Michigan, Ann Arbor; Arbor Research Collaborative for Health, Ann Arbor; U of California, Los Angeles

    Insurance type and minority status are associated with large disparities in the duration of pre-waitlisting dialysis (PWLD) among candidates for kidney transplantation. To partially redress…
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