2013 American Transplant Congress
Association between Methods of Proteinuria Screening and the Metabolic Syndrome in Potential Living Kidney Donors
Background: Proteinuria is a major risk factor for progression in chronic kidney disease. Identification of proteinuria thus may have important implications for kidney donor prognosis…2013 American Transplant Congress
Systematic Study of Causes of Death and Allograft Loss in Pancreas Transplantation in the Modern Era with ATG Induction and Tacrolimus Based Triple Immunosuppression
Endocrinology, Mayo Clinic, Rochester, MN
Background: Improved surgical techniques, modern immunosuppressive regimens, and a better understanding of donor and recipient risk factors have led to excellent short-term graft survival after…2013 American Transplant Congress
Development of Micro Bioscaffold as a Multiplex System To Evaluate Bioactive Molecules That Enhance Cell Function
Introduction: This study focuses on creating two types of micro biomimetic scaffolds: natural bioscaffold derived from decellularized liver and micron-scale biodegradable polylactide scaffolds infused with…2013 American Transplant Congress
Impaired Effector/Memory CD8+ T Cell Response Delays Acute Allograft Rejection in Older Recipients
Surgery, Brigham and Women's Hospital, Boston, MA
Background: Over the past decade, the proportion of patients over the age of 65, both, waiting for and receiving transplants has increased dramatically. It is…2013 American Transplant Congress
Comparison of Protein A-Immuno-Adsorption and Conventional Plasma Exchanges for Anti-HLA Desensitization
Nephrology, Dialysis, Transplantation, University Hospital, Saint-Etienne, France
Plasma exchanges therapy is traditionally part of anti-HLA desensitization strategies used in kidney transplantation. As compared to conventional techniques of plasma exchanges (PE) (plasma-centrifugation or…2013 American Transplant Congress
“Spontaneous” Reduction in Donor Specific Allo-Antibody (DSA) after Positive Cross Match Kidney Transplantation (+XMKTx) Is Associated with Improved Histology
Introduction.In a recent study (AJT,2011;11:2405), eculizumab decreased the incidence of early antibody mediated rejection(AMR) after +XMKTx. Post-transplant plasma exchange (PE) was not routinely used thus…2013 American Transplant Congress
Pattern of Utilization and Graft Outcomes of Patients Received Kidney Transplants from Deceased Donors < 4 Years, The
Kidneys from donors < 4 years remain underutilized because of the concerns of the recipient complications (bleeding, urine leak and graft thrombosis), and poor long-term…2013 American Transplant Congress
Effect of the Purinergic Inhibitor Oxidized-ATP in a Model of Islet Allograft Rejection
The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2Xs) sense the ATP, released during cell damage-activation, thus regulating T-cell activation. We aim to define the…2013 American Transplant Congress
CD8+TCR- Bone Marrow Facilitating Cells Induce Generation of IL-10-Producing Type 1 Regulatory T Cells In Vitro: A Critical Role for DOCK2 and Cell-Contact
We recently reported induction of high levels of chimerism and donor-specific tolerance without GVHD in mismatched related and unrelated kidney transplant recipients through administration of…2013 American Transplant Congress
Backdating Waiting Time to Date of First Maintenance Dialysis Significantly Reduces Median Time To Transplant for Kidney Transplant Candidates with Long Pre-Waitlisting Dialysis Duration
Insurance type and minority status are associated with large disparities in the duration of pre-waitlisting dialysis (PWLD) among candidates for kidney transplantation. To partially redress…
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