ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Incidence of Subclinical Rejection and De Novo Donor Specific Antibodies in Calcineurin Sparing Regimens

    T. Sandes-Freitas, C. Felipe, E. Campos, M. Soares, H. Tedesco, M. Franco, J. Medina-Pestana

    Nephrology, Universidade Federal de São Paulo, São Paulo, Brazil; Pathology, Universidade Federal do Paraná, Curitiba, Brazil; Pathology, Universidade Federal de São Paulo, São Paulo, Brazil

    Introduction: The incidence and impact of subclinical acute rejection (SCR) and of emergence of donor specific antibodies (DSA) on renal graft function remains poorly understood,…
  • 2013 American Transplant Congress

    Optimizing Kidney Exchange with Transplant Chains: Theory and Reality

    J. Dickerson, A. Procaccia, T. Sandholm

    Computer Science Department, Carnegie Mellon University, Pittsburgh, PA

    We explore the theoretical and empirical efficacy of long altruist-initiated chains in kidney exchange programs. Kidney exchange, where needy patients swap incompatible donors with each…
  • 2013 American Transplant Congress

    Extent of Donor Smoking and Mid-Term Outcomes after Lung Transplantation – A Single Center Analysis

    A. Sabashnikov, D. Garcia, P. Mohite, B. Zych, M. Capoccia, A. Popov, A. Moza, F. De Robertis, M. Amrani, T. Barahmi, M. Carby, A. Reed, A. Simon

    Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, Middlesex, United Kingdom; Thoracic and Cardiovascular Surgery, University Hospital Goettingen, Goettingen, Germany; Respiratory and Transplant Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, Middlesex, United Kingdom

    Objective In this study we retrospectively evaluated impact of donor history and extent of smoking on mid-term outcome after LTx.Methods Between 01.2007 and 09.2012, 237…
  • 2013 American Transplant Congress

    High Frequency of Valganciclovir Under- and Overdosing for CMV Prophylaxis after Renal Transplantation

    O. Rissling, M. Naik, S. Brakemeier, A. Hohberger, H. Neumayer, K. Budde

    Department of Nephrology, Charite-Universitätsmedizin Berlin CCM, Berlin, Germany

    The correct valganciclovir (vgc) dose for CMV-prophylaxis depends on renal function as assessed by the Cockroft Gault formula (CG-eGFR) for patients (pts) after transplantation (Tx).We…
  • 2013 American Transplant Congress

    Strategy for Eliminating Passenger Leukocytes in Human Renal Allografts, A

    L. Brasile, P. Glowacki, N. Henry, B. Stubenitsky

    Breonics, Inc., Albany; University Medical Center, Utrecht, Netherlands

    Transplantation is unique immunologically due to both donor and recipient antigen presenting cells being present at reperfusion. Dendritic cells (DC) are a potent type of…
  • 2013 American Transplant Congress

    Donor HSCs from the Bone Component of Vascularized Composite Allografts Migrate to Recipient Thymus and Differentiate to Mature T Cells

    R. Sucher, C. Lin, D. Zhang, W. Zhang, J. Grahammer, J. Pratschke, W. Lee, S. Schneeberger, X. Zheng, G. Brandacher

    Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Insbruck, Austria; Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore; Starzl Transplant Institute, UPMC, Pittsburgh

    Introduction:Vascularized composite allografts (VCA) feature an inexhaustible source of donor HSCs, which under proper immunomodulation might be able to migrate into the recipient’s thymus and…
  • 2013 American Transplant Congress

    Serum Cystatin C in Renal Transplantation: Beyond GFR Estimation, a Prognosis Marker?

    I. Masson, N. Maillard, E. Alamartine, C. Mariat

    Nephrology, Dialysis, Transplantation, University Hospital, Saint-Etienne, France

    In renal transplantation, death with a functioning graft remains one of the main causes of graft loss. In the general population, renal function impairment is…
  • 2013 American Transplant Congress

    Post-Transplant Complement Binding DSA: Higher Risk of Kidney Allograft Loss

    C. Lefaucheur, A. Loupy, D. Vernerey, C. Suberbielle, X. Jouven, C. Legendre, D. Glotz, A. Zeevi

    Kidney Transplantation, Saint-Louis Hospital, Paris, France; Kidney Transplantation, Necker Hospital, Paris, France; Paris Cardiovascular Research Centre, INSERM, UMR-S970, Paris, France; Histocompatibility, Saint-Louis, Paris, France; University of Pittsburgh, Pittsburgh, PA

    Anti-HLA antibodies are a major obstacle to transplantation success. We hypothesized that the complement binding capacity of anti-HLA antibodies assessed in the recipient sera could…
  • 2013 American Transplant Congress

    Kidney Re-Transplantation (reTx) in Patients with Post-Transplant Lymphoproliferative Disorder (PTLD)

    S. Lankireddy, A. Kukla, H. Ibrahim, A. Matas, N. Issa

    Renal Diseases and Hypertension, University of Minnesota, Minneapolis; Transplant Surgery, University of Minnesota, Minneapolis

    PTLD is a serious and potentially fatal complication of solid organ transplantation (Tx). It represents a spectrum of tumors ranging from benign lymphoid proliferation to…
  • 2013 American Transplant Congress

    Regulation of microRNA in Ischemia Reperfusion Injury in Heart Transplantation, The

    L. Zhou, N. Johnston, X. Zhang, D. Cheng, L. Sui, P. Luke, A. Jevnikar, W. Min, X. Zheng

    University of Western Ontario, London, Canada; Lawson Health Research institute, London, Canada

    Background: MicroRNAs (miRNA) are single-stranded RNAs containing 18-24 nucleotides in length and have emerged as a prominent class of gene regulators. Due to their capacity…
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