2013 American Transplant Congress
Immunosuppression after Renal Allograft Failure: A Survey of US Practices
Little data exists to guide the management of immunosuppression after renal graft failure. More aggressive tapering of immunosuppressive medications may reduce the risk of infection,…2013 American Transplant Congress
Association between Methods of Proteinuria Screening and the Metabolic Syndrome in Potential Living Kidney Donors
Background: Proteinuria is a major risk factor for progression in chronic kidney disease. Identification of proteinuria thus may have important implications for kidney donor prognosis…2013 American Transplant Congress
Systematic Study of Causes of Death and Allograft Loss in Pancreas Transplantation in the Modern Era with ATG Induction and Tacrolimus Based Triple Immunosuppression
Endocrinology, Mayo Clinic, Rochester, MN
Background: Improved surgical techniques, modern immunosuppressive regimens, and a better understanding of donor and recipient risk factors have led to excellent short-term graft survival after…2013 American Transplant Congress
Development of Micro Bioscaffold as a Multiplex System To Evaluate Bioactive Molecules That Enhance Cell Function
Introduction: This study focuses on creating two types of micro biomimetic scaffolds: natural bioscaffold derived from decellularized liver and micron-scale biodegradable polylactide scaffolds infused with…2013 American Transplant Congress
Impaired Effector/Memory CD8+ T Cell Response Delays Acute Allograft Rejection in Older Recipients
Surgery, Brigham and Women's Hospital, Boston, MA
Background: Over the past decade, the proportion of patients over the age of 65, both, waiting for and receiving transplants has increased dramatically. It is…2013 American Transplant Congress
Complement Component 3 (C3) Participates in Induction of Myeloid Suppressor Cells
It was noted that liver transplants in mice are spontaneously accepted, but hepatocyte transplants acutely rejected, suggesting the immunoregulatory activities of liver non-parenchymal cells. We…2013 American Transplant Congress
Impact of Deceased Donor Intensive Care Unit Management Parameters on Early Liver Graft Function
Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN
Objective:The Indiana Organ Procurement Organization (IOPO) has adopted deceased donor intensive care unit (ICU) management parameters to optimize placement of transplant organs. It is unknown…2013 American Transplant Congress
Prospective, Iterative, Phased, Trial of Proteasome Inhibitor-Based Desensitization in Highly Sensitized Renal Transplant Candidates, A
Substantive prospective trials of proteasome inhibitor (PI)-based desensitization (DS) have not been reported. This study prospectively evaluated PI-based DS in highly HLA sensitized kidney transplant…2013 American Transplant Congress
Dissecting the Contribution of Cross-Reactivity to the Preformed T Cell Response to Donor-Alloantigen in HIV+ Kidney and Liver Transplant Patients
Department of Surgery, University of California San Francisco, San Francisco, CA
Background: Despite immunodeficiency of CD4+ T cells, HIV+ kidney and liver transplant patients experience higher rejection rates compared to HIV- patients. Most of the rejection…2013 American Transplant Congress
Killer Immunoglobulin-Like Receptor (KIR) Mismatches and KIR-HLA-C Interactions Do Not Affect Short Term Graft Function in Kidney Transplantation
Human Leucocyte Antigen (HLA) matching is an important factor in long term graft survival in kidney transplantations. Natural Killer (NK) cells with their MHC recognizing…
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