ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Impact of Deceased Donor Intensive Care Unit Management Parameters on Early Liver Graft Function

    G. Marshall, R. Mangus, A. Tector

    Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN

    Objective:The Indiana Organ Procurement Organization (IOPO) has adopted deceased donor intensive care unit (ICU) management parameters to optimize placement of transplant organs. It is unknown…
  • 2013 American Transplant Congress

    Prospective, Iterative, Phased, Trial of Proteasome Inhibitor-Based Desensitization in Highly Sensitized Renal Transplant Candidates, A

    E. Woodle, B. Sadaka, R. Walsh, A. Shields, A. Girnita, P. Brailey, R. Alloway, M. Cardi, A. Govil, B. Abu Jawdeh, P. Roy Chaudhury, G. Mogilishetty

    U of Cincinnati, Cincinnati, OH; Hoxworth Blood Center, Cincinnati; Hoxworth Blood Center, Cincinnati; The Christ Hospital, Cincinnati

    Substantive prospective trials of proteasome inhibitor (PI)-based desensitization (DS) have not been reported. This study prospectively evaluated PI-based DS in highly HLA sensitized kidney transplant…
  • 2013 American Transplant Congress

    Dissecting the Contribution of Cross-Reactivity to the Preformed T Cell Response to Donor-Alloantigen in HIV+ Kidney and Liver Transplant Patients

    M. Mintz, E. Chuu, P. Stock, Q. Tang

    Department of Surgery, University of California San Francisco, San Francisco, CA

    Background: Despite immunodeficiency of CD4+ T cells, HIV+ kidney and liver transplant patients experience higher rejection rates compared to HIV- patients. Most of the rejection…
  • 2013 American Transplant Congress

    Crossmatch Positive Liver Transplantation: Role of Underlying Liver Disease

    C. Kubal, R. Mangus, R. Saxena, A. Lobashevsky, N. Higgins, A. Shah, R. Vianna, J. Fridell, J. Tector

    Department of Surgery, Division of Transplantation, Indiana University, Indianapolis, IN; Department of Pathology, Indiana University, Indianapolis, IN; Department of Transplant Immunology, Indiana University, Indianapolis, IN

    Significance of positive crossmatch in liver transplantation (LT) remains unclear. We evaluated the role of flow cytometry crossmatch (CM) in 1000 consecutive LT with a…
  • 2013 American Transplant Congress

    Creatinine (Creat) and Cystatin C (CysC) Based Glomerular Filtration Rate (GFR) Estimating Equations Are More Precise Than Creatinine-Only-Based Equations in Former Living Kidney Donors

    N. Issa, A. Kukla, S. Jackson, S. Riad, A. Matas, H. Ibrahim

    Renal Diseases and Hypertension, University of Minnesota, Minneapolis; Transplant Surgery, University of Minnesota, Minneapolis

    Background: The application of GFR estimating equations and classification schema for chronic kidney disease (CKD) has inadvertently led to labeling of some former living kidney…
  • 2013 American Transplant Congress

    Killer Immunoglobulin-Like Receptor (KIR) Mismatches and KIR-HLA-C Interactions Do Not Affect Short Term Graft Function in Kidney Transplantation

    E. Eksioglu-Demiralp, M. Elbasi, F. Ture-Ozdemir, A. Tulunay, I. Tatli-Aydin, A. Turkmen, B. Kocak

    Tissue Typing and Immunology, Istanbul Memorial Hospital, Transplantation Unit, Istanbul, Turkey; Basic Immunology, Marmara University, School of Medicine, Istanbul, Turkey; Transplantation Unit, Istanbul Memorial Hospital, Istanbul, Turkey

    Human Leucocyte Antigen (HLA) matching is an important factor in long term graft survival in kidney transplantations. Natural Killer (NK) cells with their MHC recognizing…
  • 2013 American Transplant Congress

    Increasing Resistance in Gramnegative Bacilli Causing Urinary Tract Infection (UTI) in Two Cohorts of Kidney Transplant (KT) Recipients: An Emerging Problem

    J. Origüen, F. López-Medrano, A. Pérez-Jacoiste, A. García-Reyne, N. Carrasco, M. Orellana, A. Andrés, J. Morales, J. Aguado

    Hospital 12 de Octubre, Madrid, Spain

    BackgroundUTI is the most common infection following KT. The increasing resistance in gramnegative bacilli could have an special impact on this population.MethodsTwo cohorts were followed…
  • 2013 American Transplant Congress

    Early Protocol Biopsies Can Identify Antibody-Mediated Rejection in Sensitized Patients

    P. Souza, D. Machado, A. Aguirre, D. David, E. Barbosa, F. de Paula, W. Nahas, E. David-Neto, M. Castro

    Renal Transplant Service, Hospital das Clinicas University of São Paulo, São Paulo, Brazil

    HLA sensitized patients are at risk for antibody-mediated rejection (ABMR). Our purpose was to evaluate the importance of early protocol biopsies. From Jul/2010 to Jun/2012,…
  • 2013 American Transplant Congress

    Normothermic Acellular Ex Vivo Liver Perfusion (NEVLP): Development of a New Method for the Storage, Assessment, and Repair of Marginal Liver Grafts

    M. Boehnert, J. Knaak, O. Adeyi, P. Yip, N. Selzner, G. Levy, S. Keshavjee, D. Grant, M. Selzner

    Department of Surgery, Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada; Department of Pathology, Toronto General Hospital, Toronto, ON, Canada; Department of Clinical Chemistry, Toronto General Hospital, Toronto, ON, Canada; Department of Surgery, Toronto Lung Transplant Program, Toronto General Hospital, Toronto, ON, Canada

    We compared the novel normothermic acellular ex vivo liver perfusion (NEVLP) with conventional cold static organ preservation for livers retrieved after cardiac death.Methods: Pig livers…
  • 2013 American Transplant Congress

    Vasculopathic Risk Factors for Delayed Graft Function in Kidney Transplantation

    A. Ghaffari, C. Ellington, R. Colombo, S. Baer, L. Huber, A. Guha, M. Whitlow, P. Chebrolu, N. Nahman, Jr., K. Kintziger, T. Merchen

    Surgery, Georgia Health Sciences University, Augusta; Medicine, Georgia Health Sciences University, Augusta; Biostatistics, Georgia Health Sciences University, Augusta; Medicine, Charlie Norwood VAMC, Augusta

    Background: Delayed graft function (DGF) is defined as the need for dialysis within the first week following kidney transplantation. DGF is a major risk factor…
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