ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Utility of Procalcitonin in Differentiating Infection from Rejection in Pediatric Liver-Small Bowel Transplant Patients

    R. Lirio, A. Trauernicht, R. Chaplin, W. Grant, A. Langnas, R. Quiros-Tejeira

    GI/Transplant, University of Nebraska Medical Center, Omaha, NE; Pediatric Intensive Care, University of Nebraska Medical Center, Omaha, NE

    Background: Procalcitonin (PCT) has been shown to be an effective biomarker for bacterial sepsis. Its utility has also been noted in post liver transplant patients.…
  • 2013 American Transplant Congress

    Antibody-Mediated Injury Is the Major Cause of Late Kidney Allograft Failure

    R. Gaston, R. Leduc, F. Cosio, S. Gourishankar, J. Grande, L. Hunsicker, B. Kasiske, R. Mannon, A. Matas, D. Rush, M. Cecka

    UAB, Birmingham; U Minnesota, Minneapolis; Mayo Clinic, Rochester; U Alberta, Edmonton, Canada; U Iowa, Iowa City; Hennepin County Med Ctr, Minneapolis; U Manitoba, Winnipeg, Canada; UCLA Immunogenetics Laboratory, Los Angeles

    DeKAF is NIH-funded multicenter observational study of late kidney graft failure with over 4500 recs enrolled from 2006-10. The Cross-Sectional cohort (CS, N=559) includes recs…
  • 2013 American Transplant Congress

    Colorectal Surgery after Kidney Transplant: Characteristics of Early vs. Late Post-Transplant Interventions

    J. Lee, M. Kwaan, A. Sirany, G. Melton, R. Madoff, T. Dunn

    Department of Surgery, Division of Colon and Rectal Surgery, University of Minnesota, Minneapolis, MN; Department of Surgery, Hennepin County Medical Center, Minneapolis, MN; Department of Surgery, Division of Transplantation, University of Minnesota, Minneapolis, MN

    Aim: We hypothesized that kidney transplant recipients undergoing colorectal surgery <1 year of transplant would have more complications than those >1 year post-transplant.Methods: We reviewed…
  • 2013 American Transplant Congress

    Kidney Intragraft DSA as Determinant of Antibody-Mediated Lesions and Poor Graft Outcome

    T. Bachelet, L. Couzi, S. Lepreux, M. Legeret, G. Pariscoat, G. Guidicelli, P. Merville, J. Taupin

    CHU Bordeaux, Bordeaux, Gironde, France; CNRS. UMR 5164, Bordeaux, Gironde, France; Université Bordeaux Segalen, Bordeaux, Gironde, France

    Allograft pathology, antibody-tissue interaction as demonstrated by C4d deposition, and serologic evidence of donor-specific antibodies (DSA) are the cardinal diagnostic features of antibody-mediated lesions (AML)…
  • 2013 American Transplant Congress

    Immunoregulatory Effects of Bone Marrow and Adipose Derived Stem Cells – An In Vitro Comparison

    L. Wu, N. Yuan, J. Christensen, Z. Ibrahim, G. Furtmüller, A. Leto Barone, S. Zhu, S. Schneeberger, W. Lee, D. Cooney, G. Brandacher

    Department of Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD

    Background: Direct comparison of the immunoregulatory properties of mesenchymal stem cells derived from bone marrow (BMSCs) and adipose tissue (ASCs) has not been performed to…
  • 2013 American Transplant Congress

    Interactive Web-Based Patient Portal for the Evaluation of Potential Kidney Transplant Recipients

    A. Webber, S. Tomlanovich, M. Parente, J. Roberts, R. Hirose

    Kidney Transplant Service, UCSF, San Francisco, CA

    Introduction: UCSF implemented newly available information technology to increase access to patients, improve communication, and expedite patient work-up. Using a validated(1-2) web-based software platform (BREEZE…
  • 2013 American Transplant Congress

    Proteinkinase C Epsilon Contributes to Impairment of Renal Blood Flow and Inflammation in Renal Ischemia Reperfusion Injury (IRI)

    N. Rüskamp, D. Walacides, R. Song, K. Hüper, M. Mengel, M. Meier, D. Wacker, M. Schiffer, H. Haller, F. Gueler

    Nephrology, Medical School Hannover, Hannover, Germany; Radiology, Medical School Hannover, Hannover, Germany; Applied Genomics Center, University of Alberta, Edmonton, Canada

    Background – Proteinkinase C (PKC) isoforms are invovled in several signaling pathways contributing to ischemia reperfusion injury (IRI) and acute transplant rejection. Here we investigated…
  • 2013 American Transplant Congress

    RBC Transfusions Are Associated with HLA Allosensitization in Patients Awaiting Kidney Transplantation

    B. Bradbury, M. Leffell, D. Kim, J. Petersen, J. Hart, J. Rossert, R. Vega, A. Zachary

    JHU Immunogenetics Laboratory, Johns Hopkins Uninversity School of Medicine, Baltimore, MD; Amgen, Thousand Oaks, CA

    Introduction: HLA sensitization remains a major barrier to successful kidney transplantation resulting in prolonged wait times, lower transplant rates, and decreased graft survival. This study…
  • 2013 American Transplant Congress

    MicroRNA Profile Associated with Increased Graft Damage Post Liver Transplantation

    R. Gehrau, V. Mas, J. Suh, M. Wardus, B. Kane, D. Maluf

    UVA, Charlottesville

    Background: Variable graft injury severity post ischemia reperfusion injury (IRI) is observed post liver transplantation (LT). Graft function recovery and performance are linked to this…
  • 2013 American Transplant Congress

    Complement Component 3 (C3) Participates in Induction of Myeloid Suppressor Cells

    C. Hsieh, H. Chou, L. Wang, F. Lin, J. Qin, J. Fung, L. Lu, S. Qian

    Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH; General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH; Pathology, Case Western Reserve University, Cleveland, OH

    It was noted that liver transplants in mice are spontaneously accepted, but hepatocyte transplants acutely rejected, suggesting the immunoregulatory activities of liver non-parenchymal cells. We…
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