2013 American Transplant Congress
Treatment of Late Onset De Novo Donor Specific Antibody (DSA)-Mediated Pediatric Kidney Transplant Rejection with Bortezomib
Background: In pediatric renal transplantation late onset de novo DSA leading to antibody-mediated rejection (AMR) has a poor prognosis. Our disappointing results with IVIG, rituximab…2013 American Transplant Congress
Recipient Death and Graft Loss in Renal Transplantation: The Challenge of Infectious Complications
Hospital do Rim e Hipertensão, Sao Paulo, Brazil
Introduction: The causes of recipient death and renal allograft loss are still under evaluated, and there might be several differences according to the era of…2013 American Transplant Congress
Pregnancy Outcomes in Liver Recipients Transplanted for Biliary Atresia
The purpose of this study was to describe pregnancy outcomes in female liver recipients who received a transplant due to biliary atresia. Data were collected…2013 American Transplant Congress
IL-33 Expands ST2+ Regulatory T Cells Promoting Allograft Survival Directly and Indirectly through Actions on Myeloid Dendritic Cells
Background: IL-33 is an IL-1 cytokine that signals via ST2, which is expressed on both T cells and myeloid cells. IL-33 has been ascribed Th2…2013 American Transplant Congress
Long Term Survival of PEGylated Murine Allogenic Islets Using Short Course Immunomodulation
Islet transplantation is a promising therapy for Type 1 diabetes; however, inflammatory and immune host responses lead to islet dysfunction and destruction. Cell surface PEGylation…2013 American Transplant Congress
CD8+ Cytotoxic T Cells Inhibit Alloantibody Production by Killing Alloprimed B Cells
Introduction- While it is well known that CD4+ T cells and B cells collaborate for antibody (Ab) production, our group has recently reported a novel…2013 American Transplant Congress
Effects of Human Alpha-1-Antitrypsin (hAAT) Therapy in a Murine Model of Bilateral Kidney Ischemia-Reperfusion Injury
AIM: Several lines of evidence have demonstrated the anti-inflammatory and cytoprotective effects of alpha-1-Antitrypsin (AAT), the major serum serine-protease inhibitor. The aim of the present…2013 American Transplant Congress
Total Plasma Exchange Does Not Improve Allograft Outcome in Deceased Donor Liver Transplant When Performed for Allograft Dysfunction and Positive Cross-Match
BACKGROUND: Although total plasma exchange (TPE) has been used in ABO incompatibility, and in cases of allograft dysfunction particularly in the presence of a positive…2013 American Transplant Congress
Factors Associated with Renal Dysfunction at 12 Months Following Liver Transplantation
Introduction: Renal dysfunction (RD) before and after liver transplantation (LTx) is a significant predictor of graft failure (GF). We investigated the association of donor and…2013 American Transplant Congress
Novel Role of PI3K Delta Inhibition in Both T and B Cell Activation in Alloimmunity, The
Renal, Brigham and Women's Hospita, Boston, MA
The PI3K family of dual lipid and protein kinases phosphorylates Akt into pAkt, triggering kinase cascades downstream that play a central role in cell proliferation…
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