ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Major Neurological Complications Following Renal Transplantation

    G. Basso, M. Cristelli, D. Bichuetti, M. Franco, A. Baptista, T. Sandes-Freitas, L. Gusuma, P. Gomes, H. Tedesco, J. Medina- Pestana

    Nephrology Division, Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Introduction: Major neurological complications can add significant morbidity and mortality to renal transplant and have frequencies ranging from 6 to 30% in all transplant recipients.Objective:…
  • 2013 American Transplant Congress

    Thrombin Generation and Platelet Activation in a Xenogenic Lung Perfusion Model Determine Survival of GalTKO.hCD46 Transgenic Lungs

    L. Burdorf, E. Rybak, T. Zhang, A. Riner, G. Braileanu, X. Cheng, C. Phelps, D. Ayares, A. Azimzadeh, R. Pierson III

    Surgery, University of Maryland, Baltimore, MD; Revivicor, Inc., Blacksburg, VA

    Purpose: As previously reported, the development of GalTKO pigs with additional expression of hCD46 has contributed to a significantly improved outcome of lungs in an…
  • 2013 American Transplant Congress

    Frailty and Early Hospital Readmission after Kidney Transplantation

    M. McAdams-DeMarco, A. Law, M. Salter, J. Walston, D. Segev

    Johns Hopkins University School of Medicine, Baltimore, MD

    BACKGROUND: Early hospital readmission (EHR) after kidney transplantation (KT) is associated with increased morbidity, transplant costs, and risk of transition-of-care errors. Registry-based recipient, transplant, and…
  • 2013 American Transplant Congress

    Blocking C3a/C5a-Receptor Signaling Promotes Induction and Stability of Murine and Human Alloreactive Regulatory T Cells

    W. van der Touw, C. Paolo, K. Wing, H. Peter

    Immunology Institute, Mount Sinai School of Medicine, New York, NY

    Adoptive transfer of CD4+Foxp3+ regulatory T cells (Treg) has potential for promoting transplantation tolerance but is limited by the scarcity of thymic-derived Treg and the…
  • 2013 American Transplant Congress

    Pregnancy Outcomes in Solid Organ Transplant Recipients with Exposure to Sirolimus

    S. Constantinescu, L. Coscia, M. Moritz, C. McGrory, C. Ramirez, V. Armenti

    Medicine, Temple University School of Medicine, Philadelphia; Surgery, Thomas Jefferson University, Philadelphia; Surgery, Lehigh Valley Health Network, Allentown, PA; National Transplantation Pregnancy Registry, Philadelphia

    The purpose of this study was to describe pregnancy outcomes with exposure to sirolimus. Data were collected by the National Transplantation Pregnancy Registry (NTPR) via…
  • 2013 American Transplant Congress

    Abnormal Distribution of B-Cell Populations Associated with Impaired Regulatory Functions in Chronic Antibody Mediated Rejection

    A. Nouël, I. Segalen, A. Grall, J. Pers, S. Hillion, Y. Le Meur

    EA2216 Immunology and Pathology, University of Brest, Brest, France; Nephrology, CHRU Cavale Blanche, Brest, France

    Chronic antibody (Ab) mediated rejection (cAMR) represents the major problem in renal transplantation. The aim of our study was to analyze B lymphocyte (LB) distribution…
  • 2013 American Transplant Congress

    Hanging Donors: Are We Still Skeptical about Those Lungs?

    P. Mohite, D. Saez, A. Sabashnikov, B. Zych, N. Patil, A. Moza, F. DeRobertis, T. Bahrami, M. Amrani, A. Reed, M. Carby, A. Simon

    Department of Cardiothoracic Transplantation & Mechanical Support, Royal Brompton and Harefield NHS Trust, Harefireld, Middlesex, United Kingdom

    PurposeSuicidal hanging causes compression of the neck blood vessels and the airway leading to hypoxic brain damage due to cerebral ischemia and respiratory distress. Hanging,…
  • 2013 American Transplant Congress

    Update on Phase 2 Clinical Trial To Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients

    J. Leventhal, M. Abecassis, J. Miller, L. Gallon, K. Ravindra, D. Tollerud, B. King, M. Elliott, G. Herzig, R. Herzig, S. Ildstad

    Northwestern University, Chicago, IL; Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; James Graham Brown Cancer Ctr, University of Louisville, Louisville, KY; Regenerex, LLC, Louisville, KY

    19 subjects have been enrolled in a phase 2 protocol (FDA IDE 13947) to induce tolerance in mismatched recipients of living donor renal allografts (KTx).…
  • 2013 American Transplant Congress

    Mesenchymal Stem Cell Therapy To Promote Functional Recovery in a Limb Transplant Model

    E. Fitzpatrick, M. DeHart, J. Tercero, T. Brown, S. Salgar

    Clinical Investigation, MAMC; Surgery, Madigan Army Medical Center, Tacoma, WA

    Introduction: Hand and leg transplantation (Tx) in military and civilian populations is increasingly needed to improve the quality of life of individuals. Optimizing nerve regeneration…
  • 2013 American Transplant Congress

    Product of Donor Age and Preoperative MELD, D−MELD, Predicts Surgical Outcomes after LDLT in HCV Positive Recipients, but Not in HCV Negative Recipients, The

    A. Tanemura, S. Mizuno, N. Kuriyama, Y. Azumi, I. Osawa, M. Kishiwada, M. Usui, H. Sakurai, M. Tabata, S. Isaji

    Hepatobiliary-Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan

    Background:Donor age and MELD score are recognized as risk factors affecting recipient outcomes in living donor liver transplantation (LDLT). The aim of this study is…
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