2013 American Transplant Congress
Product of Donor Age and Preoperative MELD, D−MELD, Predicts Surgical Outcomes after LDLT in HCV Positive Recipients, but Not in HCV Negative Recipients, The
Background:Donor age and MELD score are recognized as risk factors affecting recipient outcomes in living donor liver transplantation (LDLT). The aim of this study is…2013 American Transplant Congress
Undetected Lesion as a Risk Factor for Recurrence in Patients Transplanted for HCC, The
NYU SOM, New York, NY; U of M, Ann Arbor, MI
Background: OLT is the definitive treatment for HCC. Vascular invasion, tumor size, and proliferation are known risk factors for recurrence post-OLT. Undetected lesions <1cm are…2013 American Transplant Congress
Peripheral Expression of Inflammatory Proteins and miRNAs Expression at the Time of Biopsy Proven ACR and Persistence of Immune Activation Long after Clinical Resolution
The aim of this exploratory study was to determine whether inflammatory proteins and/or miRNA in serum specimens collected at the time of biopsy-proven rejection (ACR),…2013 American Transplant Congress
Children Develop De Novo Anti-HLA Antibodies (Abs) Following Kidney Transplantation at a Higher Incidence Than Adults: An Analysis of the NIH CTOT/CCTPT-02 Study
The NIH CTOT/CCTPT-02 examined the development of post transplant de novo anti-HLA Abs in unsensitized kidney transplant recipients. It is a multi-center observational study that…2013 American Transplant Congress
Influence of Steroid Maintenance on the Outcomes in Sensitized Kidney Transplant Recipients
Steroid withdrawal protocols are increasingly used in kidney transplantation. However, sensitized patients considered high immune risk are maintained on steroid by many centers. It is…2013 American Transplant Congress
IL37 Controls IL18 Induced Pro-Inflammatory Cytokine Expression by Tubular Cells and Attenuates Renal Ischemia-Reperfusion Injury
IL37 is a newly described member of the IL-1 family,which is anti-inflammatory by its inhibition of pro-inflammatory cytokine production. While human IL37 has no murine…2013 American Transplant Congress
Compartmentalization of Acute Versus Chronic Rejection in Cardiac Allografts
Immunology, Cleveland Clinic, Cleveland, OH
Acute rejection of cardiac allografts is characterized by interstitial infiltrates and diagnosed by endomyocardial biopsies. In contrast, chronic rejection is distinguished by vasculopathy in large…2013 American Transplant Congress
Rapamycin-Induced Augmentation of the CD8 T Cell Response to a Latent Viral Infection Is Inhibited by CTLA4-Ig
Latent viral infections are a major concern among immunosuppressed transplant patients. Treatment with belatacept, a CTLA4-Ig fusion protein, was shown to reduce toxicity in kidney…2013 American Transplant Congress
Impact of Cholecalciferol Repletion on Alloreactivity in Vitamin D-Deficient Hemodialysis Patients: A Randomized Controlled Trial
Dept of Medicine, Mount Sinai School of Medicine, NY, NY
Background: 25OH-Vit D deficiency is common in hemodialysis (HD) patients despite therapy with 1,25OH-Vit D, and is associated with increased T cell memory. The purpose…2013 American Transplant Congress
Epitope Matching Outperforms Traditional Antigen Matching as a Predictor of De Novo Donor Specific Antibody Development after Renal Transplantation
Hypothesis:An epitope based HLA matching approach will be predictive of de novo Donor Specific Antibody (dnDSA) development after renal transplantation.Methods:315 consecutive renal transplants were performed…
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