ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Effect of Pre-Transplant Serum Sodium on Survival Benefit of Liver Transplantation

    P. Sharma, D. Schaubel, N. Goodrich, R. Merion

    Gastroenterology, University of Michigan, Ann Arbor; Biostatistics, University of Michigan, Ann Arbor; Arbor Research Collaborative for Health, Ann Arbor; Surgery, University of Michigan, Ann Arbor

    Background: Hyponatremia is associated with higher waitlist mortality among end stage liver disease candidates awaiting liver transplantation(LT). However, studies show that such candidates also have…
  • 2013 American Transplant Congress

    Role of eGFR Equations in Evaluating Deceased Donors for Kidney Transplantation: Sufficient and Appropriate Outcome Markers?

    M. Burdese, M. Priora, M. Messina, M. Tamagnone, G. Daidola, F. Fop, L. Biancone, G. Segoloni

    University of Turin, Chair of Nephrology, Turin, Italy

    Donor evaluation is crucial in organ allocation for kidney graft, especially with the growing use of ECDs. Donor kidney function is decisive to predict graft…
  • 2013 American Transplant Congress

    Results of a Phase 2 Safety, Efficacy, and Pharmacokinetic Study of TOL-101, an Anti-TCR Monoclonal Antibody for the Prophylaxis of Acute Rejection in Kidney Transplantation

    S. Flechner, S. Mulgaonkar, L. Melton, T. Waid, R. Sung, F. Shihab, A. Wiseman, D. Getts

    Cleveland Clinic Foundation, Cleveland; Barnabas Health, West Orange; Dallas Transplant Institute, Dallas Fort Worth; Tolera Therapeutics Inc, Kalamazoo; University of Kentucky, Lexington; University of Michigan, Ann Arbor; University of Utah, Salt Lake city; University of Colorado, Denver; Northwestern University, Chicago

    Purpose: Induction therapy using anti-lymphocytic antibodies is a potent tool for the prevention of early rejection after kidney transplantation. TOL-101, an IgM monoclonal antibody, with…
  • 2013 American Transplant Congress

    Major Neurological Complications Following Renal Transplantation

    G. Basso, M. Cristelli, D. Bichuetti, M. Franco, A. Baptista, T. Sandes-Freitas, L. Gusuma, P. Gomes, H. Tedesco, J. Medina- Pestana

    Nephrology Division, Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Introduction: Major neurological complications can add significant morbidity and mortality to renal transplant and have frequencies ranging from 6 to 30% in all transplant recipients.Objective:…
  • 2013 American Transplant Congress

    Thrombin Generation and Platelet Activation in a Xenogenic Lung Perfusion Model Determine Survival of GalTKO.hCD46 Transgenic Lungs

    L. Burdorf, E. Rybak, T. Zhang, A. Riner, G. Braileanu, X. Cheng, C. Phelps, D. Ayares, A. Azimzadeh, R. Pierson III

    Surgery, University of Maryland, Baltimore, MD; Revivicor, Inc., Blacksburg, VA

    Purpose: As previously reported, the development of GalTKO pigs with additional expression of hCD46 has contributed to a significantly improved outcome of lungs in an…
  • 2013 American Transplant Congress

    Frailty and Early Hospital Readmission after Kidney Transplantation

    M. McAdams-DeMarco, A. Law, M. Salter, J. Walston, D. Segev

    Johns Hopkins University School of Medicine, Baltimore, MD

    BACKGROUND: Early hospital readmission (EHR) after kidney transplantation (KT) is associated with increased morbidity, transplant costs, and risk of transition-of-care errors. Registry-based recipient, transplant, and…
  • 2013 American Transplant Congress

    Blocking C3a/C5a-Receptor Signaling Promotes Induction and Stability of Murine and Human Alloreactive Regulatory T Cells

    W. van der Touw, C. Paolo, K. Wing, H. Peter

    Immunology Institute, Mount Sinai School of Medicine, New York, NY

    Adoptive transfer of CD4+Foxp3+ regulatory T cells (Treg) has potential for promoting transplantation tolerance but is limited by the scarcity of thymic-derived Treg and the…
  • 2013 American Transplant Congress

    Pregnancy Outcomes in Solid Organ Transplant Recipients with Exposure to Sirolimus

    S. Constantinescu, L. Coscia, M. Moritz, C. McGrory, C. Ramirez, V. Armenti

    Medicine, Temple University School of Medicine, Philadelphia; Surgery, Thomas Jefferson University, Philadelphia; Surgery, Lehigh Valley Health Network, Allentown, PA; National Transplantation Pregnancy Registry, Philadelphia

    The purpose of this study was to describe pregnancy outcomes with exposure to sirolimus. Data were collected by the National Transplantation Pregnancy Registry (NTPR) via…
  • 2013 American Transplant Congress

    Abnormal Distribution of B-Cell Populations Associated with Impaired Regulatory Functions in Chronic Antibody Mediated Rejection

    A. Nouël, I. Segalen, A. Grall, J. Pers, S. Hillion, Y. Le Meur

    EA2216 Immunology and Pathology, University of Brest, Brest, France; Nephrology, CHRU Cavale Blanche, Brest, France

    Chronic antibody (Ab) mediated rejection (cAMR) represents the major problem in renal transplantation. The aim of our study was to analyze B lymphocyte (LB) distribution…
  • 2013 American Transplant Congress

    Hanging Donors: Are We Still Skeptical about Those Lungs?

    P. Mohite, D. Saez, A. Sabashnikov, B. Zych, N. Patil, A. Moza, F. DeRobertis, T. Bahrami, M. Amrani, A. Reed, M. Carby, A. Simon

    Department of Cardiothoracic Transplantation & Mechanical Support, Royal Brompton and Harefield NHS Trust, Harefireld, Middlesex, United Kingdom

    PurposeSuicidal hanging causes compression of the neck blood vessels and the airway leading to hypoxic brain damage due to cerebral ischemia and respiratory distress. Hanging,…
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