2013 American Transplant Congress
Renal Transplantation with Final Allocation Based on the Virtual Crossmatch: Outcomes at 5 Years
Background: Use of the virtual crossmatch (VC) has been shown to increase the efficiency of identifying compatible renal transplant recipients from a given donor. However…2013 American Transplant Congress
Lymphotoxin Regulates Treg Entry into the Lymph Node
University of Maryland, Baltimore
Introduction: Lymphotoxin (LT) regulates the organization, development, and maintenance of lymphoid organs. Lymphotoxin beta receptor (LTΒR) signaling has been implicated in T cell migration in…2013 American Transplant Congress
Donor-Derived Dendritic Cells (DC) Mobilized from Cardiac Allografts Initiate T-Cell Allo-Recognition through the Direct Pathway Via Recipient’s DC
The mechanism(s) by which donor and recipient APC, in particular dendritic cells (DC), prime T cells with direct and indirect allo-specificities in lymphoid organs remains…2013 American Transplant Congress
Enoxaparin Targets Heparanase To Elicit Its Anti-Metastatic Activity
Rationale: Extracellular matrix (ECM) remodeling plays an important role in cancer development. Heparanase is an endo-Β-glycosidase that degrades the ECM heparan sulfate (HS), thereby enhancing…2013 American Transplant Congress
Analysis of Survival and Neoplasm Recurrence in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma: Association with Immunohistochemical Profile and Tumor Characteristics
Unit of Liver Transplantation, State University of Campinas, Campinas, São Paulo, Brazil
Introduction: Although overall survival rates have been around 70% after five years, recurrence of hepatocellular carcinoma (HCC) has indices in literature ranging from 6 to…2013 American Transplant Congress
KPC Infection – A Real Threat to Kidney Transplant Recipients
Hospital do Rim e Hipertensão, Sao Paulo, Brazil
Introduction: Carbapenemase-producing enterobacteriaceae (KPC) infection has become a world public health issue since its first detection in 1996. Intuitively, immunocompromised patients might be at higher…2013 American Transplant Congress
Survival of Free and Encapsulated Islet Xenografts Transplanted in the Mouse Bone Marrow, The
Objectives: Bone marrow (BM) has been recently shown to be an alternative and potentially immune-privileged site for islet transplantation. The aim of the study was…2013 American Transplant Congress
Therapy with mTOR Inhibitors in Polyomavirus Nephropathy: A Five Year Follow Up
Background: Polyomavirus nephropathy (PVAN) has a negative impact on renal allograft survival, and its treatment remains controversial. Therapy options include reduction of immunosuppressive drugs and…2013 American Transplant Congress
In Situ Quantification of 1,3-Galactosyl Transferase Knockout Swine Liver Protein Production Using Quantitative Comparative ELISA
Department of Surgery, MGH, Boston, MA; Transplant Biology Research Center, MGH, Charlestown, MA
Background: Inception of GalT knock out (GalT-KO) miniature swine has helped to ameliorate rapid xenograft rejection, now allowing for investigations into the utility of miniature…2013 American Transplant Congress
Treg Express a Unique Pattern of Trafficking Molecules and Differentially Rely on LFA-1 for Migration Compared to Effector T Cells
University of Maryland, Baltimore
Introduction: Selective interference with or enhancement of Treg function and/or migration are potentially therapeutically useful. However, to date the molecules which govern Treg migration seem…
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