ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Impact of the Determination of HLA Antibodies in Kidney Transplant over Ten Years of Monitoring

    J. Apaza, E. Gonzalez, E. Gutierrez, A. Andres, N. Polanco, I. Bengoa, L. Garcia Puente, M. Molina, J. Morales

    Nephrology, Hospital 12 de Octubre, Madrid, Spain

    Objetive: The goal of this study was to determine the prevalence of anti-HLA antibodies and the clinical outcome in patients with functioning renal graft over…
  • 2013 American Transplant Congress

    Everolimus (RAD001) Treatment Effect in Liver Transplantation – A Rational Approach To Quantify the mTOR Effect

    G. Junge, T. Dumortier, L. Fischer, S. Kohler, J. Fung

    The H2304 Study Group, Basel, Switzerland

    Background: 12M study results of study CRAD001H2304 (NCT00622869) demonstrated superior renal function and comparable efficacy, including fewer and less severe treated BPAR with everolimus (EVR)…
  • 2013 American Transplant Congress

    Anti-HLA DP Alpha Alloantibodies Are Associated with High Antibody Levels and Correlate with Individual HLA-DP Beta Epitopes in Renal Transplant Candidates and Recipients

    A. Girnita, P. Brailey, E. Portwood, M. Cardi, A. Govil, G. Mogilishetty, R. Alloway, E. Woodle

    University of Cincinnati, Cincinnati

    Anti-HLA DP antibodies have been associated with renal allograft rejection and/or positive crossmatches. While the reactivity of anti-HLA DP Beta antibody (DPΒ-Ab) is described, less…
  • 2013 American Transplant Congress

    Increased Incidence of Non Anastomotic Biliary Strictures in Case of Donation after Circulatory Death Versus Donation after Brain Death Liver Transplantation but Equivalent Graft and Patient Survival

    N. Meurisse, S. Vanden Bussche, I. Jochmans, V. Heedfeld, R. Aerts, W. Laleman, S. Van der Merwe, C. Verslype, D. Cassiman, W. Van Steenbergen, F. Nevens, J. Pirenne, D. Monbaliu

    Abdominal Transplant Surgery Department, University Hospital Leuven, Leuven, Belgium; Hepatology Department, University Hospital Leuven, Leuven, Belgium

    Because of the concerns regarding short & long-term outcomes after Liver Transplantation (LTx) using Donation after Circulatory Death (DCD) compared to Donation after Brain Death…
  • 2013 American Transplant Congress

    Renal Transplantation with Final Allocation Based on the Virtual Crossmatch: Outcomes at 5 Years

    C. Johnson, Y. Zhu, M. Zhang, B. Shames, A. Roza, D. Cronin, S. Hariharan, J. Schiller, T. Ellis

    Departments of Surgery, Medicine and Biostatistics, Medical College of Wisconsin, Milwaukee, WI; The Blood Center of Wisconsin, Milwaukee, WI

    Background: Use of the virtual crossmatch (VC) has been shown to increase the efficiency of identifying compatible renal transplant recipients from a given donor. However…
  • 2013 American Transplant Congress

    Treg Express a Unique Pattern of Trafficking Molecules and Differentially Rely on LFA-1 for Migration Compared to Effector T Cells

    C. Brinkman, J. Bromberg

    University of Maryland, Baltimore

    Introduction: Selective interference with or enhancement of Treg function and/or migration are potentially therapeutically useful. However, to date the molecules which govern Treg migration seem…
  • 2013 American Transplant Congress

    KPC Infection – A Real Threat to Kidney Transplant Recipients

    M. Cristelli, G. Basso, E. Costa-Neto, D. Lopes, T. Sandes-Freitas, V. Silva, A. Gales, S. Moreira, H. Tedesco, J. Medina- Pestana

    Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Introduction: Carbapenemase-producing enterobacteriaceae (KPC) infection has become a world public health issue since its first detection in 1996. Intuitively, immunocompromised patients might be at higher…
  • 2013 American Transplant Congress

    Survival of Free and Encapsulated Islet Xenografts Transplanted in the Mouse Bone Marrow, The

    R. Meier, J. Seebach, P. Morel, R. Mahou, D. Bosco, T. Berney, L. Buhler, Y. Muller

    Visceral and Transplantation Surgery, Cell Isolation and Transplantation Center, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Division of Clinical Immunology and Allergology, Department of Internal Medicine, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Laboratory of Chemical Biotechnology, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

    Objectives: Bone marrow (BM) has been recently shown to be an alternative and potentially immune-privileged site for islet transplantation. The aim of the study was…
  • 2013 American Transplant Congress

    Therapy with mTOR Inhibitors in Polyomavirus Nephropathy: A Five Year Follow Up

    A. Esteves, L. Camargo, L. Ulisses, G. Rivelli, M. Mazzali

    Division of Nephrology-School of Medical Sciences, State University of Campinas, Campinas, Sao Paulo, Brazil

    Background: Polyomavirus nephropathy (PVAN) has a negative impact on renal allograft survival, and its treatment remains controversial. Therapy options include reduction of immunosuppressive drugs and…
  • 2013 American Transplant Congress

    In Situ Quantification of 1,3-Galactosyl Transferase Knockout Swine Liver Protein Production Using Quantitative Comparative ELISA

    M. Hertl, I. Wamala, J. Fraser, Z. Machaidze, C. Schuetz, N. Elias, M. Varma, K. Kim, B. Cosimi, J. Markmann, D. Sachs

    Department of Surgery, MGH, Boston, MA; Transplant Biology Research Center, MGH, Charlestown, MA

    Background: Inception of GalT knock out (GalT-KO) miniature swine has helped to ameliorate rapid xenograft rejection, now allowing for investigations into the utility of miniature…
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