ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Lymphotoxin Regulates Treg Entry into the Lymph Node

    C. Brinkman, J. Bromberg

    University of Maryland, Baltimore

    Introduction: Lymphotoxin (LT) regulates the organization, development, and maintenance of lymphoid organs. Lymphotoxin beta receptor (LTΒR) signaling has been implicated in T cell migration in…
  • 2013 American Transplant Congress

    Donor-Derived Dendritic Cells (DC) Mobilized from Cardiac Allografts Initiate T-Cell Allo-Recognition through the Direct Pathway Via Recipient’s DC

    Q. Liu, D. Rojas-Canales, S. Divito, W. Shufesky, A. Larregina, A. Morelli

    Dept. of Surgery, T.E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; Dept. of Dermatology, University of Pittsburgh, Pittsburgh, PA

    The mechanism(s) by which donor and recipient APC, in particular dendritic cells (DC), prime T cells with direct and indirect allo-specificities in lymphoid organs remains…
  • 2013 American Transplant Congress

    Enoxaparin Targets Heparanase To Elicit Its Anti-Metastatic Activity

    S. Djaafar, G. Mentha

    Cellular Transplantation Division, University Hospital of Geneva, Geneva, Switzerland; Surgery, University Hospital of Geneva, Geneva, Switzerland

    Rationale: Extracellular matrix (ECM) remodeling plays an important role in cancer development. Heparanase is an endo-Β-glycosidase that degrades the ECM heparan sulfate (HS), thereby enhancing…
  • 2013 American Transplant Congress

    Analysis of Survival and Neoplasm Recurrence in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma: Association with Immunohistochemical Profile and Tumor Characteristics

    E. Ataide, R. Stucchi, T. Pereira, J. Almeida, C. Escanhoela, I. Boin

    Unit of Liver Transplantation, State University of Campinas, Campinas, São Paulo, Brazil

    Introduction: Although overall survival rates have been around 70% after five years, recurrence of hepatocellular carcinoma (HCC) has indices in literature ranging from 6 to…
  • 2013 American Transplant Congress

    Early Indicators of Kidney Graft Injury Mediated by Class II Donor Specific Antibodies (DSAII)

    E. Rodrigo, L. Cornell, B. Chopra, H. Amer, P. Dean, M. Stegall, F. Cosio

    Nephrology, Transplant Center, Mayo Clinic, Rochester, MN; Pathology, Transplant Center, Mayo Clinic, Rochester, MN; Surgery, Transplant Center, Mayo Clinic, Rochester, MN

    Introduction. Pre-transplant DSAII is associated with chronic antibody mediated rejection/transplant glomerulopathy (TG) and high risk of graft loss (GL). However, not all DSAII result in…
  • 2013 American Transplant Congress

    Expanding the Limits of the Expanded Criteria Donor

    L. Assis, M. Cristelli, T. Claudia, S. Miranda, M. Franco, T. Sandes-Freitas, M. Salenave, H. Tedesco, J. Medina- Pestana

    Nephrology Division, Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Background: Use of grafts from expanded criteria donors (ECD) has increased significantly in recent years. Acceptable reported outcomes may increase the limits of acceptance and…
  • 2013 American Transplant Congress

    Risk Factors in Venous Thrombosis of Renal Grafts from Deceased Non Heart-Beating Donors

    M. Molina, E. Gonzalez, N. Polanco, L. Garcia-Puente, A. Sevillano, E. Gutierrez, E. Morales, A. Hernandez, J. Morales, A. Andres

    Nephrology, Hospital 12 Octubre, Madrid, Spain

    Background: The deceased donor kidney transplant to non heart-beating may have a higher rate of venous thrombosis (VT).The aim of this study is to analyze…
  • 2013 American Transplant Congress

    Encapsulated Human Mesenchymal Stem Cells Reduce Alpha-Smooth Muscle Actin and Increase Matrix Metalloproteinase-9 Expression during Liver Fibrosis

    R. Meier, R. Mahou, P. Morel, Y. Muller, P. Christofilopoulos, C. Wandrey, C. Gonelle-Gispert, L. Buhler

    Visceral and Transplantation Surgery, Surgical Research Unit, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Laboratory of Chemical Biotechnology, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland; Orthopedic Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland

    INTRODUCTION: Mesenchymal stem cells (MSCs) transplantation has been suggested to be effective for the treatment of liver fibrosis, but the mechanisms of action are not…
  • 2013 American Transplant Congress

    Practices and Attitudes toward Donor Pain Control in Adult to Adult Living Donor Liver Transplantation Cohort Study (A2ALL)

    E. Pomfret, M. Simpson, D. Ladner, M. Mandell

    Lahey Clinic; Northwestern U; U of Colorado

    IntroductionClinicians at 9 A2ALL centers were surveyed about practices and attitudes toward pain control after donor hepatectomy.MethodsResponses were collected via Survey Monkey. A surgeon (S),…
  • 2013 American Transplant Congress

    Immunosuppression Regimen and the Risk of Acute Rejection in HIV-Infected Kidney Transplant Recipients

    J. Locke, N. James, S. Mehta, P. Pappas, R. Mannon, N. Desai, R. Montgomery, D. Segev

    University of Alabama at Birmingham, Birmingham; Johns Hopkins University, Baltimore

    Background: Kidney transplantation has been established as the therapy of choice for the treatment of end stage renal disease among appropriately selected HIV-infected (HIV+) individuals.…
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