ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    When Next of Kin Don't Want Their Deceased Family Members To Donate: A Survey of U.S. Organ Procurement Organizations (OPOs)

    W. Chon, M. Josephson, E. Gordon, A. Naik, A. Desai, J. Thistlethwaite, Y. Becker, P. Witkowski, L. Ross

    Nephrology, University of Chicago, Chicago, IL; Transplant Surgery, University of Chicago, Chicago, IL; Comprehensive Transplant Center, Northwestern University, Chicago, IL

    Background: The legal concept of First Person Authorization is based on the principle that the decision to donate by a person with decision-making capacity should…
  • 2013 American Transplant Congress

    Impact of Intravenous Immunoglobulins on Anti-HLA Immunization after Renal Allograft Nephrectomy

    C. Leibler-Romand, M. Matignon, F. Roudot-Thoraval, L. Salomon, D. Charron, P. Lang, C. Jacquelinet, C. Suberbielle, P. Grimbert

    Nephrology-Transplantation, Henri Mondor, APHP, Créteil, France; Public Health, Henri Mondor, APHP, Créteil, France; Urology, Henri Mondor, APHP, Créteil, France; Histocompatibility, Saint Louis, APHP, Paris, France; Agence de la Biomédecine, Saint-Denis, France

    IntroductionRenal allograft nephrectomy is a major risk factor for anti-HLA alloimmunization and antibody-mediated rejection after retransplantation. No preventive strategy has been evaluated.MethodsWe retrospectively analyzed anti-HLA…
  • 2013 American Transplant Congress

    Protective Effect of Nrf2-keap1 Pathway on Islet Cells Using Islet Isolation Model

    S. Li, Y. Masuda, M. Hajighasemi-Ossareh, A. Le, J. Chan, C. Foster, N. Vaziri, H. Ichii

    Department of Surgery, University of California, Irvine, CA; Pathology & Laboratory Medicine, University of California, Irvine, CA; Department of Medicine, University of California, Irvine, CA

    Background: Nuclear factor erythroid-derived 2-related factor (Nrf2) is a transcription factor that regulates basal activity and coordinated induction of numerous genes encoding antioxidant and phase…
  • 2013 American Transplant Congress

    B Cells from Operational Tolerant Produce More IL10, Display a Defect of Late Differentiation and Harbor a Higher Susceptibility to Cell Death Apoptosis

    M. Chesneau, A. Pallier, F. Braza, G. Lacombe, S. Le Gallou, M. Giral, R. Danger, P. Guerif, L. Michele, J. Soulilou, N. Degauque, K. Tarte, S. Brouard

    Institut National de la Santé et de la Recherche Medicale INSERM U 1064, Nantes, France; INSERM UMR 917, Université de Rennes 1, , Rennes, France; Centre HospitalierUniversitaire, Hotel Dieu, Nantes, France; Université de Na tes, Faculté de Médecine, Nantes, France; Centre Hospitalier Universitaire, Pontchaillou Rennes, Rennes, France

    Objectives: Patients operationally tolerant to a kidney graft display a whole blood transcriptional B-cell signature. As these patients only rarely develop an allo-immune response, we…
  • 2013 American Transplant Congress

    Effectiveness in Kidney Donation of Uncontrolled Donation after Cardiac Death (UDCD) Program with Out-of-Hospital Deceased People

    A. Andrés, M. Molina, E. Gonzalez, A. Sevillano, E. Gutierrez, N. Polanco, L. Garcia Puente, M. Praga, C. Carriedo, J. Morales, A. Mateos

    Nephrology, H. 12 Octubre, Madrid, Spain; SESCAM, Castilla la Mancha, Spain; SUMMA 112, Madrid, Spain

    Thousands of people suffer out-of-hospital cardiac arrest worldwide every year, death being declared in situ after 30min. of unsuccessful advanced CPR maneuvers. Some cases could…
  • 2013 American Transplant Congress

    West Nile Virus (WNV) Epidemic during 2012 in the Western United States: High Number of IgM Anti-WNV Reactives but No WNV RNA+ Organ Donors

    C. Chinchilla-Reyes, T. Mone, L. Stocks, R. Taguibao, M. Nowicki

    Mendez National Institute of Transplantation, Los Angeles; University of Southern California, Los Angeles; OneLegacy, Los Angelex; LifeSharing, San Diego

    WNV is a neurotropic flavivirus. Humans are accidental, dead-end hosts for WNV. Symptoms usually develop 2-15 days after exposure and viremia begins prior to symptoms…
  • 2013 American Transplant Congress

    Everolimus (RAD001) Treatment Effect in Liver Transplantation – A Rational Approach To Quantify the mTOR Effect

    G. Junge, T. Dumortier, L. Fischer, S. Kohler, J. Fung

    The H2304 Study Group, Basel, Switzerland

    Background: 12M study results of study CRAD001H2304 (NCT00622869) demonstrated superior renal function and comparable efficacy, including fewer and less severe treated BPAR with everolimus (EVR)…
  • 2013 American Transplant Congress

    Anti-HLA DP Alpha Alloantibodies Are Associated with High Antibody Levels and Correlate with Individual HLA-DP Beta Epitopes in Renal Transplant Candidates and Recipients

    A. Girnita, P. Brailey, E. Portwood, M. Cardi, A. Govil, G. Mogilishetty, R. Alloway, E. Woodle

    University of Cincinnati, Cincinnati

    Anti-HLA DP antibodies have been associated with renal allograft rejection and/or positive crossmatches. While the reactivity of anti-HLA DP Beta antibody (DPΒ-Ab) is described, less…
  • 2013 American Transplant Congress

    Increased Incidence of Non Anastomotic Biliary Strictures in Case of Donation after Circulatory Death Versus Donation after Brain Death Liver Transplantation but Equivalent Graft and Patient Survival

    N. Meurisse, S. Vanden Bussche, I. Jochmans, V. Heedfeld, R. Aerts, W. Laleman, S. Van der Merwe, C. Verslype, D. Cassiman, W. Van Steenbergen, F. Nevens, J. Pirenne, D. Monbaliu

    Abdominal Transplant Surgery Department, University Hospital Leuven, Leuven, Belgium; Hepatology Department, University Hospital Leuven, Leuven, Belgium

    Because of the concerns regarding short & long-term outcomes after Liver Transplantation (LTx) using Donation after Circulatory Death (DCD) compared to Donation after Brain Death…
  • 2013 American Transplant Congress

    Renal Transplantation with Final Allocation Based on the Virtual Crossmatch: Outcomes at 5 Years

    C. Johnson, Y. Zhu, M. Zhang, B. Shames, A. Roza, D. Cronin, S. Hariharan, J. Schiller, T. Ellis

    Departments of Surgery, Medicine and Biostatistics, Medical College of Wisconsin, Milwaukee, WI; The Blood Center of Wisconsin, Milwaukee, WI

    Background: Use of the virtual crossmatch (VC) has been shown to increase the efficiency of identifying compatible renal transplant recipients from a given donor. However…
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