ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Rejection Phenotypes, Rejection Timing and Kidney Transplant Outcome

    M. Naesens, D. Kuypers, K. De Vusser, Y. Vanrenterghem, E. Lerut

    University Hospitals Leuven, Leuven, Belgium

    BACKGROUNDThe relative impact of different types of T-cell mediated rejection (borderline changes [BAR], grade 1 or grade 2-3 T-cell mediated rejection [TCMR]) and of antibody-mediated…
  • 2013 American Transplant Congress

    Comparison of Efficacy and Mechanism of Intact and Fc-Modified Anti-CD154 Antibodies in Tolerance Induction

    D. Pinelli, D. Liu, M. Wagener, A. Suri, S. Nadler, M. Ford

    Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ

    Blockade of CD40-CD154 interactions during T cell priming has been shown to be a highly effective means of inducing long-term survival of allografts and transplantation…
  • 2013 American Transplant Congress

    CD68 Positive Glomerulitis Predicts the Development of Transplant Glomerulopathy in Patients with Cellular Rejection

    M. Willicombe, C. Roufosse, P. Brookes, J. Galliford, A. McLean, T. Cook, D. Taube

    Imperial College Kidney and Transplant Centre, London, United Kingdom; Histopathology Department, Imperial College NHS Trust, London, United Kingdom

    Transplant glomerulopathy [TG] has a very poor prognosis and is almost always associated with eventual graft failure. The risk of TG is increased in patients…
  • 2013 American Transplant Congress

    C1q-Fixing Human Leukocyte Antigen Antibodies Identified by a C1q Assay Are Associated with Acute and Chronic Rejection in HLA-IgG Positive Kidney Transplant Recipients

    E. Oh, K. Park, Y. Kim, B. Chung, C. Yang

    Laboratory Medicine, Catholic University, Seoul, Republic of Korea; Medical Cell Biology, Department of Biomedical Science, Graduate School, Catholic University, Seoul, Republic of Korea; Internal Medicine, Catholic University, Seoul, Republic of Korea

    Background: Although donor-specific HLA antibodies (DSA) are associated with antibody-mediated rejection (AMR) and poor clinical outcome in kidney transplantation, not all DSAs are harmful to…
  • 2013 American Transplant Congress

    Living Donor Conversion Rate as a Quality Measure for Kidney Transplant Programs

    E. Woodle, B. Woodle, A. Girnita, M. Cuffy, S. Shah, J. Schold, J. Gill

    U of Cincinnati, Cincinnati; Cleveland Clinic, Cleveland; U of British Columbia, Canada

    Kidney transplant (KTxp) program quality is assessed by risk adjusted wait list (WL) mortality, time to deceased donor (DD) Txp, and patient (pt) and graft…
  • 2013 American Transplant Congress

    Should All Type 1 Diabetic Patients (T1DM) Undergo Cardiac Angiography for Transplant Evaluation?

    A. Elsanjak, A. Selek, V. Vidyasagar, M. Mohamed, J. Odorico, A. Djamali, G. Leverson, H. Sollinger, J. Pirsch, D. Kaufman

    Transplant Surgery, UW Madison, Madison, WI

    Objectives: Cardiovascular disease is the leading cause of death after transplantation. Optimal work-up remains controversial. Since 2005, we have performed cardiac catheterization for all T1DM…
  • 2013 American Transplant Congress

    Early Indicators of Kidney Graft Injury Mediated by Class II Donor Specific Antibodies (DSAII)

    E. Rodrigo, L. Cornell, B. Chopra, H. Amer, P. Dean, M. Stegall, F. Cosio

    Nephrology, Transplant Center, Mayo Clinic, Rochester, MN; Pathology, Transplant Center, Mayo Clinic, Rochester, MN; Surgery, Transplant Center, Mayo Clinic, Rochester, MN

    Introduction. Pre-transplant DSAII is associated with chronic antibody mediated rejection/transplant glomerulopathy (TG) and high risk of graft loss (GL). However, not all DSAII result in…
  • 2013 American Transplant Congress

    Expanding the Limits of the Expanded Criteria Donor

    L. Assis, M. Cristelli, T. Claudia, S. Miranda, M. Franco, T. Sandes-Freitas, M. Salenave, H. Tedesco, J. Medina- Pestana

    Nephrology Division, Hospital do Rim e Hipertensão, Sao Paulo, Brazil

    Background: Use of grafts from expanded criteria donors (ECD) has increased significantly in recent years. Acceptable reported outcomes may increase the limits of acceptance and…
  • 2013 American Transplant Congress

    Risk Factors in Venous Thrombosis of Renal Grafts from Deceased Non Heart-Beating Donors

    M. Molina, E. Gonzalez, N. Polanco, L. Garcia-Puente, A. Sevillano, E. Gutierrez, E. Morales, A. Hernandez, J. Morales, A. Andres

    Nephrology, Hospital 12 Octubre, Madrid, Spain

    Background: The deceased donor kidney transplant to non heart-beating may have a higher rate of venous thrombosis (VT).The aim of this study is to analyze…
  • 2013 American Transplant Congress

    Encapsulated Human Mesenchymal Stem Cells Reduce Alpha-Smooth Muscle Actin and Increase Matrix Metalloproteinase-9 Expression during Liver Fibrosis

    R. Meier, R. Mahou, P. Morel, Y. Muller, P. Christofilopoulos, C. Wandrey, C. Gonelle-Gispert, L. Buhler

    Visceral and Transplantation Surgery, Surgical Research Unit, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland; Laboratory of Chemical Biotechnology, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland; Orthopedic Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland

    INTRODUCTION: Mesenchymal stem cells (MSCs) transplantation has been suggested to be effective for the treatment of liver fibrosis, but the mechanisms of action are not…
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