2013 American Transplant Congress
Intragraft Gene Expression of Polyomavirus Associated Nephropathy
BACKGROUNDAlthough the histopathology of polyomavirus nephropathy (PVAN) is very often indistinguishable from T-cell mediated rejection (TCMR), the outcome of both diseases is very different. The…2013 American Transplant Congress
Experience with Sorafenib in the Liver Transplant Population
U of M, Ann Arbor, MI; NYU SOM, New York, NY
Background: HCC is a common indication for OLT. TACE and RFA are used as bridge therapies. These rarely result in complete eradication. Subsequent spread throughout…2013 American Transplant Congress
Occult Hepatitis B Virus (HBV) Infections among Organ and Tissue Donors: Lessons Learned from "Real Time" Testing
Background: Currently Hepatitis B surface Antigen (HBsAg) and Hepatitis B core Antibody (anti-HBc) screening is used to reduce organ/tissue-transmitted HBV. Although this serologic testing algorithm…2013 American Transplant Congress
Causes of Kidney Transplant Failure: Specific Diseases Versus Non-Specific Injury, The
University Hospitals Leuven, Leuven, Belgium
BACKGROUNDThe relative impact on renal allograft outcome of specific histological diseases (e.g. acute T-cell mediated rejection [TCMR], acute and chronic antibody-mediated rejection [aABMR and cABMR],…2013 American Transplant Congress
Impact of Pre-Transplant Amputation on Renal Allograft Outcomes
Introduction: United States Renal Data System (USRDS) was used to assess renal allograft outcomes in patients with pre- transplant amputation (AMP).Methods: We used an incident…2013 American Transplant Congress
Validation of Urine CXCL10 for Diagnosis of Subclinical and Clinical Rejection in Pediatric Kidney Transplants
University of Manitoba, Winnipeg, Canada
Non-invasive testing for detection of acute rejection is needed to improve outcomes. Urinary CXCL10 has been validated as a biomarker of tubulitis in adults and…2013 American Transplant Congress
Lymphotoxin Regulates Treg Entry into the Lymph Node
University of Maryland, Baltimore
Introduction: Lymphotoxin (LT) regulates the organization, development, and maintenance of lymphoid organs. Lymphotoxin beta receptor (LTΒR) signaling has been implicated in T cell migration in…2013 American Transplant Congress
Donor-Derived Dendritic Cells (DC) Mobilized from Cardiac Allografts Initiate T-Cell Allo-Recognition through the Direct Pathway Via Recipient’s DC
The mechanism(s) by which donor and recipient APC, in particular dendritic cells (DC), prime T cells with direct and indirect allo-specificities in lymphoid organs remains…2013 American Transplant Congress
Enoxaparin Targets Heparanase To Elicit Its Anti-Metastatic Activity
Rationale: Extracellular matrix (ECM) remodeling plays an important role in cancer development. Heparanase is an endo-Β-glycosidase that degrades the ECM heparan sulfate (HS), thereby enhancing…2013 American Transplant Congress
Analysis of Survival and Neoplasm Recurrence in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma: Association with Immunohistochemical Profile and Tumor Characteristics
Unit of Liver Transplantation, State University of Campinas, Campinas, São Paulo, Brazil
Introduction: Although overall survival rates have been around 70% after five years, recurrence of hepatocellular carcinoma (HCC) has indices in literature ranging from 6 to…
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