ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Protective Effect of Nrf2-keap1 Pathway on Islet Cells Using Islet Isolation Model

    S. Li, Y. Masuda, M. Hajighasemi-Ossareh, A. Le, J. Chan, C. Foster, N. Vaziri, H. Ichii

    Department of Surgery, University of California, Irvine, CA; Pathology & Laboratory Medicine, University of California, Irvine, CA; Department of Medicine, University of California, Irvine, CA

    Background: Nuclear factor erythroid-derived 2-related factor (Nrf2) is a transcription factor that regulates basal activity and coordinated induction of numerous genes encoding antioxidant and phase…
  • 2013 American Transplant Congress

    B Cells from Operational Tolerant Produce More IL10, Display a Defect of Late Differentiation and Harbor a Higher Susceptibility to Cell Death Apoptosis

    M. Chesneau, A. Pallier, F. Braza, G. Lacombe, S. Le Gallou, M. Giral, R. Danger, P. Guerif, L. Michele, J. Soulilou, N. Degauque, K. Tarte, S. Brouard

    Institut National de la Santé et de la Recherche Medicale INSERM U 1064, Nantes, France; INSERM UMR 917, Université de Rennes 1, , Rennes, France; Centre HospitalierUniversitaire, Hotel Dieu, Nantes, France; Université de Na tes, Faculté de Médecine, Nantes, France; Centre Hospitalier Universitaire, Pontchaillou Rennes, Rennes, France

    Objectives: Patients operationally tolerant to a kidney graft display a whole blood transcriptional B-cell signature. As these patients only rarely develop an allo-immune response, we…
  • 2013 American Transplant Congress

    Effectiveness in Kidney Donation of Uncontrolled Donation after Cardiac Death (UDCD) Program with Out-of-Hospital Deceased People

    A. Andrés, M. Molina, E. Gonzalez, A. Sevillano, E. Gutierrez, N. Polanco, L. Garcia Puente, M. Praga, C. Carriedo, J. Morales, A. Mateos

    Nephrology, H. 12 Octubre, Madrid, Spain; SESCAM, Castilla la Mancha, Spain; SUMMA 112, Madrid, Spain

    Thousands of people suffer out-of-hospital cardiac arrest worldwide every year, death being declared in situ after 30min. of unsuccessful advanced CPR maneuvers. Some cases could…
  • 2013 American Transplant Congress

    West Nile Virus (WNV) Epidemic during 2012 in the Western United States: High Number of IgM Anti-WNV Reactives but No WNV RNA+ Organ Donors

    C. Chinchilla-Reyes, T. Mone, L. Stocks, R. Taguibao, M. Nowicki

    Mendez National Institute of Transplantation, Los Angeles; University of Southern California, Los Angeles; OneLegacy, Los Angelex; LifeSharing, San Diego

    WNV is a neurotropic flavivirus. Humans are accidental, dead-end hosts for WNV. Symptoms usually develop 2-15 days after exposure and viremia begins prior to symptoms…
  • 2013 American Transplant Congress

    Analysis of Graft Loss in Hand Transplant Recipients in the Western World – Cause for Concern?

    K. Ravindra, V. Gorantla

    Surgery, Duke University, Durham; University of Pittsburgh, Pittsburgh

    Introduction: In the 14 years since the first successful hand transplant, the procedure has become established and performed around the world. This is an analysis…
  • 2013 American Transplant Congress

    Recipient’s Conventional Dendritic Cells (DC) Are the Mediators of the Beneficial Effects of Immunosuppressive DC-Based Therapies in Cardiac Transplantation

    Z. Wang, S. Divito, D. Rojas-Canales, W. Shufesky, T. Sumpter, A. Larregina, A. Morelli

    Dept. of Surgery, T.E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; Dept. of Dermatology, University of Pittsburgh, Pittsburgh, PA

    During the past 15 years, therapies based on administration of donor- or recipient-derived immunosuppressive (IS) / tolerogenic dendritic cells (DC), alone or in combination with…
  • 2013 American Transplant Congress

    Differing Responsiveness of EQ-5D Preference Valuations to Solid Organ Transplantation: Implications for Cost-Utility Analyses

    A. Zaman, L. Dageforde, E. Zavala, A. Hameed, A. Wright, H. Ye, D. Moore, I. Feurer

    Transplant Center, Vanderbilt University Medical Center, Nashville, TN; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN

    Introduction: EuroQoL (EQ-5D) health-related quality of life surveys can be reported as health status scores and preference valuation (PV) utilities. Our aim was to evaluate…
  • 2013 American Transplant Congress

    Interleukin-1 Receptor Antagonist Delays Progression of Liver Fibrosis

    R. Meier, Y. Muller, S. Lacotte, G. Mentha, P. Morel, C. Gonelle-Gispert, L. Buhler

    Visceral and Transplantation Surgery, Surgical Research Unit, Department of Surgery, University Hospitals of Geneva, Geneva University, Geneva, Switzerland

    Introduction: Liver fibrosis represents a wound healing response to chronic insults affecting both candidates for liver transplantation and transplanted patients. Interleukin-1Β (IL1Β) has been proposed…
  • 2013 American Transplant Congress

    Have Livers? Will Travel! Multiple Listings To Expedite Liver Transplantation

    P. Vagefi, J. Dodge, S. Feng, J. Roberts

    Surgery, MGH, Boston, MA; Surgery, UCSF, San Francisco, CA

    Background Geographic disparity in access to liver transplantation (LT) exists. This study compared demographics, waitlist, and transplant dynamics of multi-listed (ML) versus singly listed (SL)…
  • 2013 American Transplant Congress

    Rabbit ATGs Modulate the Leukocyte-Endothelium Interactions in Both Naïve and Adult Endothelial Cells

    A. Beiras-Fernandez, I. Hartmann, F. Kur, I. Kaczmarek, I. Kanzler

    Cardiothoracic and Vascular Surgery, JW Goethe University, Frankfurt, Germany; Cardiac Surgery, LMU München, Munich, Germany

    IntroductionPolyclonal antithymocyte globulins (ATGs) are immunosuppressive drugs widely used in induction of immunosuppression and treatment of acute rejection after solid organ transplantation. The aim of…
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