ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Safety of Early Everolimus in De Novo Heart Transplant Recipients: Interim Analysis of the Randomized Study EVERHEART

    L. Potena, F. Barberini, M. Boffini, C. Maiello, G. Pedrazzini, G. Faggian, G. Gerosa, P. Lilla, N. Marraudino, M. Corda, S. Bernazzali, R. Guarisco, U. Livi

    AO S. Orsola Malpighi, Bologna, Italy; ASO Molinette S. Giovanni Battista, Torino, Italy; Ospedale Monaldi, Napoli, Italy; AO Niguarda Ca' Granda, Milano, Italy; Ospedale Civile Maggiore, Verona, Italy; AOU Padova, Padova, Italy; AO San Camillo Forlanini, Roma, Italy; Policlinico di Bari, Bari, Italy; AO G. Brotzu, Cagliari, Italy; AOU Senese, Siena, Italy; Novartis Farma, Origgio (VA), Italy; AOU S. Maria della Misericordia, Udine, Italy

    Recent data raised question regarding the safety of everolimus (EVR) in the early post-operative period in de novo heart transplant (HT) recipients. Thus, we have…
  • 2013 American Transplant Congress

    7 Years Experience with Multiplex TMA-NAT-Based Assay for HIV and HCV Screening among Organ and Tissue Donors – Definitive Report

    C. Chinchilla-Reyes, M. Sampaio, T. Mone, L. Stocks, R. Taguibao, P. Niles, M. Johnson, M. Nowicki

    Mendez National Institute of Transplantation, Los Angeles; University of Southern California, Los Angeles; OneLegacy, Los Angeles; LifeSharing, San Diego; New Mexico Donor Services, New Mexico; Sierra Donor Services, Sacramento

    BACKGROUND Transplant professionals must be able to rely on organ and tissue screening tests to accurately detect the presence of viruses and their antibodies. Antiviral…
  • 2013 American Transplant Congress

    Analysis of Leukocyte-Endothelium Interactions after Immunosuppression by Means of Intravital Microscopy in the Human Placenta

    A. Beiras-Fernandez, S. Walther, A. Beiras, E. Thein

    Cardiothoracic and Vascular Surgery, JW Goethe University Hospital, Frankfurt, Germany; Walter-Brendel Institute of Experimental Medicine, Munich, Germany; Universidad de Santiago de Compostela, Santiago, Spain

    Background: The failure of translating results obtained in animal models into humans is one of the main problems in medical research. The aim of our…
  • 2013 American Transplant Congress

    Rejection Phenotypes, Rejection Timing and Kidney Transplant Outcome

    M. Naesens, D. Kuypers, K. De Vusser, Y. Vanrenterghem, E. Lerut

    University Hospitals Leuven, Leuven, Belgium

    BACKGROUNDThe relative impact of different types of T-cell mediated rejection (borderline changes [BAR], grade 1 or grade 2-3 T-cell mediated rejection [TCMR]) and of antibody-mediated…
  • 2013 American Transplant Congress

    Comparison of Efficacy and Mechanism of Intact and Fc-Modified Anti-CD154 Antibodies in Tolerance Induction

    D. Pinelli, D. Liu, M. Wagener, A. Suri, S. Nadler, M. Ford

    Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ

    Blockade of CD40-CD154 interactions during T cell priming has been shown to be a highly effective means of inducing long-term survival of allografts and transplantation…
  • 2013 American Transplant Congress

    CD68 Positive Glomerulitis Predicts the Development of Transplant Glomerulopathy in Patients with Cellular Rejection

    M. Willicombe, C. Roufosse, P. Brookes, J. Galliford, A. McLean, T. Cook, D. Taube

    Imperial College Kidney and Transplant Centre, London, United Kingdom; Histopathology Department, Imperial College NHS Trust, London, United Kingdom

    Transplant glomerulopathy [TG] has a very poor prognosis and is almost always associated with eventual graft failure. The risk of TG is increased in patients…
  • 2013 American Transplant Congress

    C1q-Fixing Human Leukocyte Antigen Antibodies Identified by a C1q Assay Are Associated with Acute and Chronic Rejection in HLA-IgG Positive Kidney Transplant Recipients

    E. Oh, K. Park, Y. Kim, B. Chung, C. Yang

    Laboratory Medicine, Catholic University, Seoul, Republic of Korea; Medical Cell Biology, Department of Biomedical Science, Graduate School, Catholic University, Seoul, Republic of Korea; Internal Medicine, Catholic University, Seoul, Republic of Korea

    Background: Although donor-specific HLA antibodies (DSA) are associated with antibody-mediated rejection (AMR) and poor clinical outcome in kidney transplantation, not all DSAs are harmful to…
  • 2013 American Transplant Congress

    Living Donor Conversion Rate as a Quality Measure for Kidney Transplant Programs

    E. Woodle, B. Woodle, A. Girnita, M. Cuffy, S. Shah, J. Schold, J. Gill

    U of Cincinnati, Cincinnati; Cleveland Clinic, Cleveland; U of British Columbia, Canada

    Kidney transplant (KTxp) program quality is assessed by risk adjusted wait list (WL) mortality, time to deceased donor (DD) Txp, and patient (pt) and graft…
  • 2013 American Transplant Congress

    Should All Type 1 Diabetic Patients (T1DM) Undergo Cardiac Angiography for Transplant Evaluation?

    A. Elsanjak, A. Selek, V. Vidyasagar, M. Mohamed, J. Odorico, A. Djamali, G. Leverson, H. Sollinger, J. Pirsch, D. Kaufman

    Transplant Surgery, UW Madison, Madison, WI

    Objectives: Cardiovascular disease is the leading cause of death after transplantation. Optimal work-up remains controversial. Since 2005, we have performed cardiac catheterization for all T1DM…
  • 2013 American Transplant Congress

    Tolerance Related Gene Expression in Urine from Kidney Transplant Recipients

    M. Jenkins, M. Runglall, I. Rebollo-Mesa, P. Mobillo, Y. Kamra, E. Nova-Lamperti, S. Norris, GAMBIT Consortium, G. Lord, R. Lechler, M. Hernandez-Fuentes

    King's College London, MRC Centre for Transplantation, London, United Kingdom; NIHR Comprehensive Biomedical Research Centre, At Guy's and St Thomas' Hospital NHS Foundation Trust in Partnership with King's College London and King's College Hospital, London, United Kingdom; www.GAMBITstudy.co.uk, London, United Kingdom; King's Health Partners, London, United Kingdom

    Background: Long-term graft survival in renal transplantation relies on continuous immunosuppression with drugs that can cause high morbidity. Tolerance is an emerging clinically recognised event.…
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