2013 American Transplant Congress
Interleukin-1 Receptor Antagonist Delays Progression of Liver Fibrosis
Introduction: Liver fibrosis represents a wound healing response to chronic insults affecting both candidates for liver transplantation and transplanted patients. Interleukin-1Β (IL1Β) has been proposed…2013 American Transplant Congress
Have Livers? Will Travel! Multiple Listings To Expedite Liver Transplantation
Surgery, MGH, Boston, MA; Surgery, UCSF, San Francisco, CA
Background Geographic disparity in access to liver transplantation (LT) exists. This study compared demographics, waitlist, and transplant dynamics of multi-listed (ML) versus singly listed (SL)…2013 American Transplant Congress
Rabbit ATGs Modulate the Leukocyte-Endothelium Interactions in Both Naïve and Adult Endothelial Cells
IntroductionPolyclonal antithymocyte globulins (ATGs) are immunosuppressive drugs widely used in induction of immunosuppression and treatment of acute rejection after solid organ transplantation. The aim of…2013 American Transplant Congress
Intragraft Gene Expression of Polyomavirus Associated Nephropathy
BACKGROUNDAlthough the histopathology of polyomavirus nephropathy (PVAN) is very often indistinguishable from T-cell mediated rejection (TCMR), the outcome of both diseases is very different. The…2013 American Transplant Congress
Experience with Sorafenib in the Liver Transplant Population
U of M, Ann Arbor, MI; NYU SOM, New York, NY
Background: HCC is a common indication for OLT. TACE and RFA are used as bridge therapies. These rarely result in complete eradication. Subsequent spread throughout…2013 American Transplant Congress
Occult Hepatitis B Virus (HBV) Infections among Organ and Tissue Donors: Lessons Learned from "Real Time" Testing
Background: Currently Hepatitis B surface Antigen (HBsAg) and Hepatitis B core Antibody (anti-HBc) screening is used to reduce organ/tissue-transmitted HBV. Although this serologic testing algorithm…2013 American Transplant Congress
Causes of Kidney Transplant Failure: Specific Diseases Versus Non-Specific Injury, The
University Hospitals Leuven, Leuven, Belgium
BACKGROUNDThe relative impact on renal allograft outcome of specific histological diseases (e.g. acute T-cell mediated rejection [TCMR], acute and chronic antibody-mediated rejection [aABMR and cABMR],…2013 American Transplant Congress
Impact of Pre-Transplant Amputation on Renal Allograft Outcomes
Introduction: United States Renal Data System (USRDS) was used to assess renal allograft outcomes in patients with pre- transplant amputation (AMP).Methods: We used an incident…2013 American Transplant Congress
Validation of Urine CXCL10 for Diagnosis of Subclinical and Clinical Rejection in Pediatric Kidney Transplants
University of Manitoba, Winnipeg, Canada
Non-invasive testing for detection of acute rejection is needed to improve outcomes. Urinary CXCL10 has been validated as a biomarker of tubulitis in adults and…2013 American Transplant Congress
Urinary Protein Excretion in Non-Renal Transplant Patients – Does mTOR-Inhibitor Treatment Matter?
The H2304 Study Group, Basel, Switzerland
BackgroundThe interplay of glomerular filtration and tubular absorption of proteins with various molecular weights defines the pattern and magnitude of daily urinary protein excretion (UPE).…
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