2013 American Transplant Congress
Analysis of Leukocyte-Endothelium Interactions after Immunosuppression by Means of Intravital Microscopy in the Human Placenta
Background: The failure of translating results obtained in animal models into humans is one of the main problems in medical research. The aim of our…2013 American Transplant Congress
Rejection Phenotypes, Rejection Timing and Kidney Transplant Outcome
University Hospitals Leuven, Leuven, Belgium
BACKGROUNDThe relative impact of different types of T-cell mediated rejection (borderline changes [BAR], grade 1 or grade 2-3 T-cell mediated rejection [TCMR]) and of antibody-mediated…2013 American Transplant Congress
Comparison of Efficacy and Mechanism of Intact and Fc-Modified Anti-CD154 Antibodies in Tolerance Induction
Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ
Blockade of CD40-CD154 interactions during T cell priming has been shown to be a highly effective means of inducing long-term survival of allografts and transplantation…2013 American Transplant Congress
CD68 Positive Glomerulitis Predicts the Development of Transplant Glomerulopathy in Patients with Cellular Rejection
Transplant glomerulopathy [TG] has a very poor prognosis and is almost always associated with eventual graft failure. The risk of TG is increased in patients…2013 American Transplant Congress
C1q-Fixing Human Leukocyte Antigen Antibodies Identified by a C1q Assay Are Associated with Acute and Chronic Rejection in HLA-IgG Positive Kidney Transplant Recipients
Background: Although donor-specific HLA antibodies (DSA) are associated with antibody-mediated rejection (AMR) and poor clinical outcome in kidney transplantation, not all DSAs are harmful to…2013 American Transplant Congress
Living Donor Conversion Rate as a Quality Measure for Kidney Transplant Programs
U of Cincinnati, Cincinnati; Cleveland Clinic, Cleveland; U of British Columbia, Canada
Kidney transplant (KTxp) program quality is assessed by risk adjusted wait list (WL) mortality, time to deceased donor (DD) Txp, and patient (pt) and graft…2013 American Transplant Congress
Should All Type 1 Diabetic Patients (T1DM) Undergo Cardiac Angiography for Transplant Evaluation?
Transplant Surgery, UW Madison, Madison, WI
Objectives: Cardiovascular disease is the leading cause of death after transplantation. Optimal work-up remains controversial. Since 2005, we have performed cardiac catheterization for all T1DM…2013 American Transplant Congress
Tolerance Related Gene Expression in Urine from Kidney Transplant Recipients
Background: Long-term graft survival in renal transplantation relies on continuous immunosuppression with drugs that can cause high morbidity. Tolerance is an emerging clinically recognised event.…2013 American Transplant Congress
Face Transplantation with Combined Hematopoietic Stem Cell Infusion and Vascularized Bone Marrow Transplantation Is Not Associated with Mixed Chimerism in Humans
In rat models of limb allograft transplantation, the combination of vascularized bone marrow transplantation (VBMT) with both Csa and anti-TCR mAb is associated with the…2013 American Transplant Congress
Anti-HLA Immunization Profile at the Time and after Renal Allograft Nephrectomy
IntroductionAllograft nephrectomy is a major risk factor for alloimmunization and can increase time on the waiting-list and acute antibody-mediated rejection. Anti-HLA immunization profile, DSA and…
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