ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    AMPK Activator Promotes, but Complement and Thrombin Inhibit Anti-A/B Antibody-Induced Accommodation in Endothelial Cells

    K. Iwasaki, Y. Miwa, M. Haneda, T. Kuzuya, H. Ogawa, A. Onishi, T. Kobayashi

    Department of Transplant Immunology, Nagoya University School of Medicine, Nagoya, Japan; Department of Hospital Pharmacy, Nagoya University School of Medicine, Nagoya, Japan; Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan; National Institute of Agrobiological Sciences, Tsukuba, Japan

    [Purpose] Several efforts have been made to define the mechanisms of accommodation termed as a condition without graft rejection even in the presence of anti-donor…
  • 2013 American Transplant Congress

    Is There More Stress or Coercion To Donate in KPD Donors?

    D. Serur, M. Charlton, M. Lawton, J. Sinacore, C. Li, J. Gordon-Elliott

    Kidney and Pancreas Transplantation, NYP Weill Cornell, New York; Psychiatry, NYP Weill Cornell, New York; Nephrology, NYP Weill Cornell, Rogosin, New York; National Kidney Registry, New York

    BACKGROUND:Kidney paired donation (KPD) is growing fast. The donors in KPD, or chain donors (Ch-D), have never before been studied from a psychosocial aspect or…
  • 2013 American Transplant Congress

    Early Recurrence of Hepatocellular Carcinoma after Primary Liver Resection Is Associated with Poor Outcome of Salvage Liver Transplantation: A Multicenter Analysis of 82 Cases

    S. Lee, C. Kwon, S. Yang, H. Park, W. Cho, J. Kim, J. Park, S. Kim, J. Joh, B. Kim, H. Wang, K. Lee, K. Suh, S. Lee

    Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea; Department of Surgery, Ajou University School of Medicine, Suwon; Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

    Objective) Salvage liver transplantation (LT) is considered a feasible option for treatment of recurrent hepatocellular carcinoma (HCC), especially when living-donor LT is a possible option.…
  • 2013 American Transplant Congress

    Systematic Bias in Surgeon Predictions of Donor-Specific Risk of Liver Transplant Graft Failure

    M. Volk, R. Merion

    University of Michigan, Ann Arbor

    BACKGROUND: The decision to accept or decline a liver allograft for a patient on the transplant waiting list is complex. We hypothesized that surgeons are…
  • 2013 American Transplant Congress

    Effect of Adipose Tissue Derived Mesenchymal Stem Cells on B Cells Proliferation and Differentiation, The

    M. Franquesa, F. Mensah, R. Huizinga, M. Betjes, W. Weimar, C. Baan, M. Hoogduin

    Internal Medicine Department-Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands; Immunology Department, Erasmus MC, Rotterdam, Netherlands

    Background:Mesenchymal stem cells (MSC) have proven immunomodulatory capacity (in vitro and in vivo) which makes them a promising therapeutic tool in transplantation. However, research on…
  • 2013 American Transplant Congress

    No Inhibitory Effect of Pre-Transplant Desensitization Including Rituximab or Splenectomy on De Novo HLA Antibody Production after Kidney Transplantation

    S. Ashimine, T. Kobayashi

    Department of Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan; Department of Transplant Immunology, Nagoya University School of Medicine, Nagoya, Aichi, Japan

    BACKGROUND: The long-term effect of rituximab (RIT) and splenectomy (SPX) on de novo HLA Ab production after renal transplantation (RTx) was unclear. METHODS: We examined…
  • 2013 American Transplant Congress

    Alemtuzumab as Anti-Rejection Therapy in Kidney Transplant Patients Induces Homeostatic T Cell Proliferation and Impairs IL7 but Not IL2 Responses

    A. Bouvy, D. Hesselink, M. Klepper, W. Weimar, C. Baan

    Dept of Internal Medicine, ErasmusMC, University Medical Center, Rotterdam, Netherlands

    Introduction: Induction therapy with alemtuzumab is known to result in T cell depletion followed by a slow immune recovery leading to hypo-responsiveness to the graft.…
  • 2013 American Transplant Congress

    Multivisceral Transplantation for Unresectable Hepatoblastoma: Single Center Experience

    K. Potanos, N. Fullington, R. Cauley, K. Vakili, H. Kim

    Surgery, Boston Children's Hospital, Boston, MA

    Purpose: Optimal treatment of hepatoblastoma requires complete resection and extensive portomesenteric vascular extension provides a unique challenge.Methods:Two patients undergoing MVT for unresectable hepatoblastoma at our…
  • 2013 American Transplant Congress

    Immediate Extubation Following Pediatric Liver Transplantation: A Single Center Experience

    N. Fullington, R. Cauley, K. Potanos, C. Seefelder, H. Kim, K. Vakili

    Surgery and Anesthesia, Boston Children's Hospital, Boston, MA

    PurposeCare of pediatric liver transplant recipients has traditionally included postoperative ventilation. Since 2005, we have evaluated for immediate extubation(IE) in the operating room based on…
  • 2013 American Transplant Congress

    Spontaneous Acceptance of Mouse Islet Allografts in B Cell-Deficient Donor and Recipient Is Associated with Donor-Derived Plasmacytoid Dendritic Cells

    K. Lee, M. Lian, R. Stott, H. Yeh, S. Deng, J. Kim, J. Markmann

    Surgery/Transplantation, Massachusetts General Hospital, Boston, MA

    Spontaneous acceptance of grafts can be hightlighted by novel mechanisms of drug-free transplantation tolerance. Several animal studies showed that mouse renal allografts in certain strain…
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