2013 American Transplant Congress
Network Analysis Reveals Roles of Inflammation Factors in Different Phenotypes of Kidney Transplantation Patients
Zhongshan Hospital, Fudan University, Shanghai Key Lab of Organ Transplantation, Shanghai, China
BackgroundSystems-level characterization of inflammation in kidney transplantation remains incomplete. The present study aimed at identifying the inflammation proteins in phenotype transformation and assessing potential biomarkers…2013 American Transplant Congress
Outcomes on the Simultaneous Pancreas-Kidney (SPK) Transplant Waitlist: A Competing Risk Analysis of the UNOS Database
Kidney Transplant Research Center, UCLA David Geffen School of Medicine, Los Angeles, CA
Objective: To determine the risk of competing outcomes for patients on the waitlist for Simultaneous Pancreas-Kidney (SPK) transplantation.Design: We used the OPTN/UNOS database to examine…2013 American Transplant Congress
Donor CISH Polymorphism Is Associated with Allograft Outcomes in Kidney Transplantation
Background: Cytokine-inducible SH-2 containing protein (CISH) is a member of suppressor of cytokine signaling (SOCS) family and involved in the negative regulation of IL-2 mediated…2013 American Transplant Congress
Analysis of miRNAs in Peripheral Blood Mononuclear Cells: Potential Value of miR-182 as a Biomarker of Chronic Antibody Mediated Rejection
[Purpose] All donor specific antibodies (DSAs) cannot cause chronic antibody-mediated rejection (CAMR), as grafts of renal transplant recipients with DSAs have shown different outcomes. Although…2013 American Transplant Congress
Single Dose of Rituximab Results in a Long Lasting B-Cell Depletion in Peripheral Blood, without Affecting the Peripheral T-Cell Compartment, A
The B-cell depleting antibody rituximab is widely used for the treatment of B-cell malignancies and autoimmune disorders. In organ transplantation, it is especially applied to…2013 American Transplant Congress
PD-1 Analysis on CD28-CD27- CD4 T-Cells Allows Rapid Stimulation-Independent Assessment of CMV-Viremic Episodes in Transplant Recipients
We have previously shown that a high PD-1 expression on CMV-specific CD4 T-cells defines an anergic phenotype that is associated with CMV viremia in patients…2013 American Transplant Congress
Preformed Anti-MICA Antibodies Negatively Impact Renal Allograft Evolution in Early Post-Transplantation Period
We analyzed the role of preformed a-MICA antibodies (Abs) in kidney recipients (n=727), transplanted between 2005 and 2011. Fifty two patients (pts) had preformed a-MICA…2013 American Transplant Congress
Superior Renal Function Sustained for 24 Months through Early Everolimus-Facilitated Reduction of Tacrolimus Versus Standard Tacrolimus in De Novo Liver Transplant Recipients: Results of a Randomized Trial
mTOR inhibitors have the potential to reduce calcineurin inhibitor nephrotoxicity by minimizing or eliminating the need for their use. The 12 month (M) results of…2013 American Transplant Congress
Impact of mTOR and Calcineurin Inhibition on Lipid and Glucose Metabolism – 24 Month Assessment in De Novo Liver Transplant Recipients Treated with Everolimus and Tacrolimus
For the H2304 Investigators, Hamburg, Germany; Novartis Pharma AG, Basel, Switzerland
Immunosuppressants, particularly corticosteroids (CS) and calcineurin inhibitors used after liver transplantation (LTx) can adversely affect lipid metabolism. mTOR inhibition blocks insulin-stimulated lipoprotein lipase and can…2013 American Transplant Congress
There Is No Difference in Patient Survival after Liver Transplantation between Induction with Rabbit ATG and Basiliximab in Recipients with HCV, However, There Appears To Be Less Severe Fibrosis with rATG
University of Washington, Seattle
rATG has gained acceptance for induction in liver transplantation. However, due to its strength as an immunosuppressive agent, there is concern that it may be…
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