ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Course of BK Virus Infection in Renal Transplant Recipients Treated with Cidofovir

    S. Kuten, S. Patel, R. Knight, L. Gaber, A. Gaber

    The Methodist Hospital, Houston, TX

    In renal transplantation, BK virus may contribute to graft dysfunction and graft loss. While reduction in immunosuppression is considered standard therapy for infection, data has…
  • 2013 American Transplant Congress

    First Report of Experience Using Telaprevir with Peginterferon and Ribavirin To Treat Recurrent Hepatitis C Genotype 1 in Recipients of Liver and Kidney Transplantation

    S. Pungpapong, R. Satyanarayana, B. Rosser, M. Yataco, M. Mai, H. Wadei, T. Gonwa, A. Keaveny

    Transplantation, Mayo Clinic, Jacksonville, FL

    Background: Recurrent hepatitis C (HCV) after liver transplantation (LT) is universal and may lead to poor outcomes. Treatment with peginterferon and ribavirin (PR) after LT…
  • 2013 American Transplant Congress

    First Canadian Experience in Pediatric En-Bloc Renal Allograft Donation after Cardiac Death

    N. Rowe, M. Dion, J. Shum, C. Weernink, A. Sener, P. Luke

    Urology, Western University, London, ON, Canada; Surgery, Western University, London, ON, Canada

    Introduction: The use of small pediatric kidneys obtained from donors less than four years of age after cardiac death (DCD) has been limited. This is…
  • 2013 American Transplant Congress

    Estimated Glomerular Filtration Rate Decreases Transiently Following Repeat Heart Transplantation in Children and Young Adults

    J. Gralla, S. Auerbach, C. Connell, M. Mitchell, D. Campbell, J. Jaggers, S. Miyamoto, B. Pietra

    University of Colorado Denver, Aurora

    Background: Renal function is abnormal in patients with end stage graft failure due to hemodynamic compromise and chronic exposure to nephrotoxic medications. The purpose of…
  • 2013 American Transplant Congress

    Salvage Transplantation Aligns Survival for Small and Large Hepatocellular Carcinomas in the Modern Era of Liver Surgery

    M. Kluger, J. Salceda, A. Laurent, C. Tayar, D. Azoulay, D. Cherqui

    HPB Surgery & Liver Transplantation, NYPH-Weill Cornell Medical Center, New York; Chirurgie Hépatobiliaire, Hôpital Henri Mondor, Créteil, France

    INTRODUCTIONOperative management is standard treatment of hepatocellular carcinoma (HCC). In select patients, resection can offer cure or a bridge to transplantation. This study analyzed resection…
  • 2013 American Transplant Congress

    Analysis of miRNAs in Peripheral Blood Mononuclear Cells: Potential Value of miR-182 as a Biomarker of Chronic Antibody Mediated Rejection

    K. Iwasaki, J. Ping, T. Yamamoto, Y. Miwa, M. Haneda, Y. Watarai, A. Katayama, K. Uchida, T. Kobayashi

    Department of Transplant Immunology, Nagoya University School of Medicine, Nagoya, Japan; Nagoya Daini Red Cross Hospital, Nagoya, Japan; Masuko Memorial Hospital, Nagoya, Japan

    [Purpose] All donor specific antibodies (DSAs) cannot cause chronic antibody-mediated rejection (CAMR), as grafts of renal transplant recipients with DSAs have shown different outcomes. Although…
  • 2013 American Transplant Congress

    Single Dose of Rituximab Results in a Long Lasting B-Cell Depletion in Peripheral Blood, without Affecting the Peripheral T-Cell Compartment, A

    E. Kamburova, H. Koenen, M. van den Hoogen, I. Joosten, L. Hilbrands

    Laboratory Medicine, Medical Immunology, Radboud University Medical Centre, Nijmegen, Netherlands; Department of Nephrology, Radboud University Medical Centre, Nijmegen, Netherlands

    The B-cell depleting antibody rituximab is widely used for the treatment of B-cell malignancies and autoimmune disorders. In organ transplantation, it is especially applied to…
  • 2013 American Transplant Congress

    PD-1 Analysis on CD28-CD27- CD4 T-Cells Allows Rapid Stimulation-Independent Assessment of CMV-Viremic Episodes in Transplant Recipients

    J. Dirks, H. Tas, T. Schmidt, S. Kirsch, B. Gärtner, U. Sester, M. Sester

    Dpt of Transplant and Infection Immunology, Saarland University, Homburg, Germany; Internal Med. IV, Homburg, Germany; Microbiology, Homburg, Germany

    We have previously shown that a high PD-1 expression on CMV-specific CD4 T-cells defines an anergic phenotype that is associated with CMV viremia in patients…
  • 2013 American Transplant Congress

    Preformed Anti-MICA Antibodies Negatively Impact Renal Allograft Evolution in Early Post-Transplantation Period

    E. Sánchez-Zapardiel, M. Castro-Panete, M. Castillo-Rama, P. Morales, D. Lora-Pablos, D. Valero-Hervás, R. Ruiz-García, J. Apaza, P. Talayero, A. Amado, J. Morales, E. Paz-Artal

    Immunology, Madrid, Spain; Epidemiology, Madrid, Spain; Nephrology, H. 12 Octubre, Madrid, Spain; I+12 Research Institute, Madrid, Spain

    We analyzed the role of preformed a-MICA antibodies (Abs) in kidney recipients (n=727), transplanted between 2005 and 2011. Fifty two patients (pts) had preformed a-MICA…
  • 2013 American Transplant Congress

    Superior Renal Function Sustained for 24 Months through Early Everolimus-Facilitated Reduction of Tacrolimus Versus Standard Tacrolimus in De Novo Liver Transplant Recipients: Results of a Randomized Trial

    P. De Simone, O. Detry, G. Kintmalm, J. Goss, P. McCormick, M. Rossi, A. Moya, P. Lopez, G. Junge, G. Dong, D. Joseph, C. Duvoux

    For the H2304 Study Group, Pisa, Italy; Novartis Pharma AG, Basel, Switzerland; Novartis Pharmaceuticals Corporation, New Jersey

    mTOR inhibitors have the potential to reduce calcineurin inhibitor nephrotoxicity by minimizing or eliminating the need for their use. The 12 month (M) results of…
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