ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Do Donor Specific Antibodies Affect Graft Liver Outcomes after Living Donor Liver Transplantation?

    D. Joo, S. Song, S. Lee, M. Kim, A. Lee, J. Choi, S. Kim

    Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea

    Background: Preformed circulating donor specific antibodies (DSAs) immunologically challenge vascular endothelium and the bile duct. However, the liver is an immune tolerant organ and can…
  • 2013 American Transplant Congress

    Graft Infiltrating Foxp3 Tregs in Spontaneously Tolerant Renal A Allografts Express High Levels of CXCR3 and BLIMP-1

    M. Hu, C. Wang, G. Zhang, M. Saito, Y. Wang, M. Fernandez, Y. Qian, Y. Wang, A. Sawyer, W. Hawthorne, C. Jones, T. Sparwasser, A. Bishop, A. Sharland, P. O'Connell, S. Alexander

    CKR, Children's Hospital at Westmaed, Westmead, Australia; CTRR, Westmead Millennium Institute, University of Sydney, Wesmead, Australia; CTL, Royal Prince Alfred Hospital, Sydney, Australia; CPIR, Children's Hospital at Westmead, Westmead, Australia; Institute of Infection Immunology, Centre for Experimental and Clinical Infection Research, GmbH, Hanover, Germany

    Background: Foxp3+Tregs have an essential role in allograft tolerance. Aim: To evaluate Foxp3+Tregs in the spontaneous tolerance of mouse renal allografts. Methods: A standard mouse…
  • 2013 American Transplant Congress

    MicroRNAs (miRNAs) Identified in Human Formalin-Fixed Paraffin-Embedded (FFPE) Kidney Biopsies Regulate Acute Cellular Rejection (ACR) and Renal Allograft Functional Status

    P. Ruiz, E. Margolles-Clark, J. Sageshima, G. Ciancio, L. Chen, A. Mattiazi, G. Guerra, W. Kupin, D. Roth, G. Burke

    Surgery, University of Miami, Miami, FL; Medicine, University of Miami, Miami, FL

    Alterations of miRNA expression regulate the post-transcriptional expression of many target genes in allografts and thus likely help regulate alloreactive processes. We carried out a…
  • 2013 American Transplant Congress

    Comparison of Pediatric En-Bloc Renal Allograft Growth and Function for Donors Less Than One Year of Age with Older Pediatric Donors

    N. Rowe, M. Dion, J. Shum, C. Weernink, A. Sener, P. Luke

    Urology, Western University, London, ON, Canada

    Introduction: The use of pediatric en-bloc kidneys obtained from infant donors of very small size has previously been investigated. Some transplantation centers have under-utilized very…
  • 2013 American Transplant Congress

    Comparison of Estimated Glomerular Filtration Rate Using Cystatin C Versus Creatinine in Pediatric Renal Transplant Patients

    H. Pizzo, J. Nguyen, G. Schwartz, R. Ettenger, E. Tsai

    Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Pediatric Nephrology, University of Rochester School of Medicine, Rochester, NY

    Purpose: Analyze the accuracy of estimated glomerular filtration rate (eGFR) in pediatric renal transplant (Tx) patients (pts) using cystatin C, serum creatinine (SCr), and the…
  • 2013 American Transplant Congress

    Increased Duration of Dual Pegylated Interferon and Ribavirin Therapy for Genotype 1 Hepatitis C Post-Liver Transplantation Increases Sustained Virologic Response: A Retrospective Review

    M. Wells, P. Marotta, M. Levstik, N. Chandok, L. Roth, V. Bain, A. Mason, B. Aljudaibi

    Department of Gastroenterology and Hepatology, Western University, London, ON, Canada; General Division, The Scarborough Hospital, Scarborough, ON, Canada; University of Alberta, Edmonton, AB, Canada

    Aims: Hepatitis C–related cirrhosis is the leading indication for liver transplantation. HCV recurrence is almost universal, leading to advanced fibrosis in at least 30% of…
  • 2013 American Transplant Congress

    Graft Function Measured by Transient Elastography in Living Donor Liver Transplantation: Preliminary Results

    S. Lee, D. Joo, S. Kim, M. Kim, A. Lee, G. Choi, J. Choi, K. Han, S. Kim

    Department of Surgery, Yonsei University College of Medicine; Research Institute for Transplantation, ; Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction: Liver stiffness (LS) measurement using transient elastography (TE) provide a non-invasive means of assessing liver fibrosis and are correlated to hepatic cholestasis. However, few…
  • 2013 American Transplant Congress

    First Report of Experience Using Telaprevir with Peginterferon and Ribavirin To Treat Recurrent Hepatitis C Genotype 1 in Recipients of Liver and Kidney Transplantation

    S. Pungpapong, R. Satyanarayana, B. Rosser, M. Yataco, M. Mai, H. Wadei, T. Gonwa, A. Keaveny

    Transplantation, Mayo Clinic, Jacksonville, FL

    Background: Recurrent hepatitis C (HCV) after liver transplantation (LT) is universal and may lead to poor outcomes. Treatment with peginterferon and ribavirin (PR) after LT…
  • 2013 American Transplant Congress

    First Canadian Experience in Pediatric En-Bloc Renal Allograft Donation after Cardiac Death

    N. Rowe, M. Dion, J. Shum, C. Weernink, A. Sener, P. Luke

    Urology, Western University, London, ON, Canada; Surgery, Western University, London, ON, Canada

    Introduction: The use of small pediatric kidneys obtained from donors less than four years of age after cardiac death (DCD) has been limited. This is…
  • 2013 American Transplant Congress

    Estimated Glomerular Filtration Rate Decreases Transiently Following Repeat Heart Transplantation in Children and Young Adults

    J. Gralla, S. Auerbach, C. Connell, M. Mitchell, D. Campbell, J. Jaggers, S. Miyamoto, B. Pietra

    University of Colorado Denver, Aurora

    Background: Renal function is abnormal in patients with end stage graft failure due to hemodynamic compromise and chronic exposure to nephrotoxic medications. The purpose of…
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