2013 American Transplant Congress
Alemtuzumab Induction in Simultaneous Pancreas and Kidney Transplantation
Background: Alemtuzumab is a monoclonal anti-CD52 antibody used as an induction agent in organ transplantation. Few studies have analyzed this agent in the context of…2013 American Transplant Congress
Dynamic Composite Analyses Identify Biomarkers of Progression to Chronic Allograft Dysfunction after Kidney Transplantation
Background. Loss of kidney graft function due to interstitial fibrosis (IF) and tubular atrophy (TA) remains the main clinical challenge for long-term graft survival rate.Methods.…2013 American Transplant Congress
Endogenous Memory CD8 T Cells Are Activated To Proliferate and Express Effector Functions within Cardiac Allografts without Mediating Rejection
INTRODUCTION: We recently reported that endogenous memory CD8+ T cells infiltrate MHC-mismatched cardiac allografts and are activated to proliferate and produce IFN-Γ in response to…2013 American Transplant Congress
Reperfusion Injury in Extended Criteria Donor Liver Grafts: A Look inside the Molecular Level
UVA, Charlottesville; VCU, Richmond
Background: Organ characteristics and quality play a critical role in the degree of ischemia/reperfusion injury (IRI) and graft function, especially in marginal organs. This study…2013 American Transplant Congress
Dual Kidney Transplantation without Allocation by Preimplantation Biopsy – A Single Center Experience
Kidney transplants from expanded criteria donors (ECD) have become generally accepted due to the increasing organ shortage. Dual kidney transplantation (DKT) of marginal kidneys not…2013 American Transplant Congress
Ex-Vivo Generation of Immunosuppressive Human Cells by Co-Culture of Recipient and Irradiated Donor PBMCs under CD80/CD86 Costimulation Blockade
Purpose:We have shown that co-culture of recipient and irradiated donor splenocytes under presence of anti-CD80 and anti-CD86 mAbs generates immunosuppressive cells in-culture and induces tolerance…2013 American Transplant Congress
Outcomes of Combined Liver-Kidney Transplantation in Children: Analysis of the SRTR Registry
Background: Combined liver-kidney transplantation (CLKT) in children is uncommon. Reports on outcomes are scarce and usually on small cohorts.Methods: Using the North-American Scientific Registry of…2013 American Transplant Congress
Influence of Baseline Immunosuppresion on Renal Function and Clinical Outcomes in Liver Transplantation, The
Pharmacy, MUSC, Charleston, SC; Surgery, MUSC, Charleston, SC
Background: Preserving renal function in liver transplantation has become paramount to improving long-term survival. However, there are limited definitive studies comparing different immunosuppression (IS) regimens…2013 American Transplant Congress
Theaflavin (TF) Ameliorates Kidney Ischemia-Reperfusion Injury in Mice
Renal ischemia reperfusion injury (IRI) is a major factor responsible for acute renal failure (ARF). ARF is a common clinical morbidity, which can occur as…2013 American Transplant Congress
Portrait of CAD with IF-TA Development Post Kidney Transplantation. Proteomics as Noninvasive Biomarkers
UVA, Charlottesville; VCU, Richmond
Background: Chronic allograft dysfunction (CAD) with interstitial fibrosis-tubular atrophy (IFTA) post kidney transplantation (KT) is one of the most common causes of graft loss. This…
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