ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Does Ex-Situ Atraumatic Retrograde Hepatic Artery Perfusion in Pediatric Living Donor Liver Transplantation Reduce the Incidence of Anastomotic Biliary Strictures?

    T. Darius, J. Rivera, C. de Magnee, R. Reding

    Pediatric Liver Transplant Program, Université Catholique de Louvain, Brussels, Belgium; Transplant Unit, Fundación Cardioinfantil IC, Bogotá, Colombia

    Background. Using left living donor grafts, the local ischemia of the left bile duct stump has been suspected to play a crucial role in post-transplant…
  • 2013 American Transplant Congress

    Kidney-Induced Cardiac Allograft Tolerance across a Full MHC-Barrier in Miniature Swine

    M. Madariaga, S. Michel, M. Tasaki, V. Villani, E. Farkash, G. La Muraglia II, J. Allan, D. Sachs, K. Yamada, J. Madsen

    Cardiothoracic Transplantation Laboratory, Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    We have previously demonstrated that a kidney allograft has the ability to confer tolerance on a co-transplanted heart allograft procured from a class I-mismatched donor.…
  • 2013 American Transplant Congress

    Prevascularized Tissue-Engineered Construct Serves as an Alternative Site for Pancreatic Islet Transplantation, A

    G. Zhao, M. Yang, L. Wei, X. Huang, J. Lei, J. Markmann, S. Deng

    Department of Surgery, Sichuan Provincial People's Hospital, Chengdu, Sichuan Province, China; Transplant Unit, Massachusetts General Hospital, Boston, MA

    Although the sites for clinical or experimental islet transplantation have been well established, the pancreatic islet survival and function in homing locations still remain unsatisfied.…
  • 2013 American Transplant Congress

    Intrahepatic Natural Killer Cells Highly Expressing NKp46 Inhibit Early-Phase Post-Transplant Hepatitis C Virus Replication

    N. Tanimine, Y. Tanaka, H. Ohdan

    Department of Surgery, Hiroshima University, Hiroshima City, Kasumi 1-2-3, Minami-ku, Japan

    [Aim] The role of NK cells in pathophysiology of HCV infection was not entirely clear. Understanding the function of NK cells in HCV-infected patients may…
  • 2013 American Transplant Congress

    Heat Shock Protein 90 Is Involved in Antibody-Mediated Rejection and Is a Potential Target of Anti-Rejection Therapy in Kidney Transplantation

    T. Tanaka, H. Ishida, M. Furusawa, Y. Tamura, H. Kitamura, S. Takahashi, N. Masumori, K. Tanabe, N. Sato, T. Tsukamoto

    Urology, Sapporo Medical University, Sapporo, Japan; Urology, Tokyo Women's Medical University, Tokyo, Japan; Pathology, Sapporo Medical University, Sapporo, Japan

    Purpose: Heat shock protein 90 (HSP90) is a ubiquitously expressed molecular chaperone that is associated with the correct activation of client proteins. Important roles of…
  • 2013 American Transplant Congress

    Treatment of Cryptococcosis in Solid-OrganTransplant Recipients: Relapse Is Rare after Discontinuation of Therapy

    J. Baddley, B. Klausing, K. Brizendine, V. Kumar, B. Julian, D. Eckhoff, J. Tallaj, K. Wille, S. Moser, P. Pappas

    University of Alabama at Birmingham, Birmingham, AL; Birmingham VAMC, Birmingham, AL; Cleveland Clinic, Cleveland, OH

    Background: Cryptococcosis is the third most common fungal infection in solid- organ transplant (SOT) recipients. Current treatment guidelines recommend 6-12 months of antifungal therapy; however,…
  • 2013 American Transplant Congress

    Complement Fixing HLA Antibodies Predict Outcome in HLA Incompatible Renal Transplantation

    C. Clarke, P. Brookes, C. Lawrence, M. Willicombe, P. Dodd, E. Santos-Nunez, J. Galliford, D. Taube

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom

    HLA incompatible [HLAi] transplantation is associated with a higher incidence of antibody mediated rejection [AMR] and Transplant Glomerulopathy [TG]. In this study, we show that…
  • 2013 American Transplant Congress

    Probability of Deceased Donor Kidney Transplantation Based on PRA%

    I. Bostock, J. Alberu, A. Adriana, D. Adrian, G. Norma, L. Mayra, C. Natalia, M. Luis, G. Bernardo, V. Mario

    Transplantation Department, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Distrito Federal, Mexico; Histocompatibility Department, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Distrito Federal, Mexico

    Sensitization to HLA antigens creates an obstacle for the accessibility and success of kidney transplantation (KT). Highly sensitized patients have longer waiting times and some…
  • 2013 American Transplant Congress

    Class I HLA Mismatches Increase Risk of Acute Rejection, Graft Loss and Formation of De Novo Class II Alloantibody

    E. Casey, M. Gandhi, P. Dean, M. Stegall, F. Cosio

    Nephrology, Transplant Center, Mayo Clinic, Rochester, MN; Surgery, Transplant Center, Mayo Clinic, Rochester, MN; Pathology, Transplant Center, Mayo Clinic, Rochester, MN

    Introduction. With modern immunosuppression it is believed that HLA mismatch (mm) have little impact on kidney graft survival, except for the benefits of 0 HLA…
  • 2013 American Transplant Congress

    Urea-Modified Protein Antigens to Simultaneously Assess CMV-Specific CD4 and CD8 T-Cell Responses Using a New CMV-ELISPOT Assay and Flow-Cytometry

    D. Schub, T. Schmidt, C. Guckelmus, S. Kirsch, L. Deml, U. Sester, M. Sester

    Dpt of Transplant and Infection Immunology, Saarland University, Homburg, Germany; Lophius Biosciences, Regensburg, Germany; Internal Medicine IV, Homburg, Germany

    CMV-specific T-cell monitoring is currently explored as a valuable tool to identify transplant recipients at risk for viral complications. As both CMV-specific CD4 and CD8…
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