2013 American Transplant Congress
Selective Blockade of VLA-4 Integrin Inhibits Early Infiltration of Endogenous Memory CD8 T into Cardiac Allograft and Donor-Reactive T Cell Priming
Immunology, Cleveland Clinic, Cleveland, OH; Urology, Tokyo Women's Medical Univ, Tokyo, Japan
INTRODUCTION: We recently reported that endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts and produce IFN-Γ in response to donor class I MHC molecules…2013 American Transplant Congress
Anti-Perlecan Antibodies Are Novel Accelerators of Immune-Mediated Vascular Injury
Acute vascular rejection (AVR) is characterized by immune-mediated vascular injury and heightened endothelial cell (EC) apoptosis. We previously reported that apoptotic ECs release a bioactive…2013 American Transplant Congress
Inherited Patients: Friend or Foe?
The Purpose of our study was to investigate the role of inherited patients in transplant centers. For the purpose of this study, an inherited patient…2013 American Transplant Congress
Effect of ASP0028 in Combination with Tacrolimus on Kidney Transplantation in Cynomolgus Monkeys, The
Introduction: Sphingosine 1-phosphate (S1P) is a bioactive lipid mediator involved in many critical physiological processes including immunity. ASP0028 is a recent developed S1P1/S1P5 selective agonist.…2013 American Transplant Congress
Pretransplant Infusion of Donor Stem Cells Open Gateway to Tolerance through Induction of Regulatory T Cells and Activation of Other Allosuppressive Immune Mechanisms – Single Centre Experience in Living Donor Renal Transplantation
Introduction: Data regarding stem cell infusion (SCI) for tolerance induction in renal transplantation (RTx) is sparse. We designed a prospective trial in a cohort of…2013 American Transplant Congress
Sequential Analysis of Donor-Specific Antibodies and Pathological Findings in Acute Antibody-Mediated Rejection: A Rat Renal Transplantation Model
Background. Although clinical evidence regarding antibody- and complement-mediated injury in renal transplantation is available, the mechanism of acute antibody mediated rejection, AAMR, remains unclear. Therefore,…2013 American Transplant Congress
Pharmacokinetics and CYP3A5 Pharmacogenetics for Once- Versus Twice-Daily Tacrolimus from First Dosing Day to 1 Year Post-Transplantation
Backgrounds: Tacrolimus is available as an immediate-release, twice-daily formulation (Tac-BID), and a prolonged-release once-daily formulation (Tac-QD). A number of studies found that the daily dose…2013 American Transplant Congress
Retroperitoneoscopic Living Donor Nephrectomy Safely Provides Excellent Graft Function
BACKGROUND: Laparoscopic living donor nephrectomy has been a standard procedure of donor nephrectomy. The transperitoneal hand-assisted laparoscopic living donor nephrectomy (HALDN) has been commonly reported…2013 American Transplant Congress
Curriculum Thoracic Transplantation (CTTX): Training on Heart and Lung Explantation and Implantation
Objective:Survival of organ transplantation depends to a major part on successful organ explantation and implantation, especially in light of the increasing number of marginal donor…2013 American Transplant Congress
Hypothermic Machine Perfusion with Ulinastatin in Pancreas Preservation Improved Islet Yield and Function in Islet Isolation
Maintaining islet viability after pancreas procurement is critical for optimal graft function and survival in islet transplantation. It is recently reported that islet yield and…
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