ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Combination of Anti-BTLA Antibody (6B2) and Anti-PD-1 Antibody (PIM-2) Induced Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allograft

    X. Jin, M. Uchiyama, L. Yu, H. Bashuda, H. Yagita, M. Niimi

    Surgery, Teikyo University, Tokyo, Japan; Surgery, Harbin Medical University, Harbin, China; Immunology, Juntendo University Hospital, Tokyo, Japan

    Background: Programmed death (PD)-1 has been implicated in peripheral tolerance, and the coinhibitory receptor B and T lymphocyte attenuator (BTLA) has been implicated in the…
  • 2013 American Transplant Congress

    What Is the Best Treatment for BK Viremia after Kidney Transplantation: Results of a 5-Year Screening Study

    N. Elfadawy, S. Flechner, X. Liu, J. Schold, R. Fatica, T. Srinivas, E. Poggio, R. Avery, S. Mossad

    Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH; Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH; Infectious Disease/Medicine Institute, Cleveland Clinic, Cleveland, OH

    Purpose: Various anecdotal reports have described clinical activity of cidofovir, leflunomide, and ciprofloxacin in clearing the BK virus. Our aim was to define the factors…
  • 2013 American Transplant Congress

    Anchoring Heparin to the Surface of Islet Improved Revascularization in Islet Transplantation

    X. Tian, Y. Li, H. Song, X. Ding, X. Feng, J. Hou, W. Xue, P. Tian

    The Department of Renal Transplantation, The First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China; The Department of Osteology, The Second Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China

    Objective: We all know that the inadequate blood supply is likely contributors to islet death in the immediate posttransplant period and may impair islet survival…
  • 2013 American Transplant Congress

    Dyslipidemia in the First Year after Renal Transplantation: Its Prevalence, Associated Clinical and Genomic Factors, and Graft Survival

    K. Numakura, S. Satoh, M. Saito, N. Komine, S. Akihama, T. Inoue, S. Narita, N. Tsuchiya, T. Habuchi

    Urology, Akita University Graduate School of Medicine, Akita, Japan; Renal Replacement Therapeutic Science, Akita University School of Medicine, Akita, Japan

    Introduction and Objective: Dyslipidemia is common among renal transplant recipients and may be a risk factor for cardiovascular disease and graft dysfunction. The present study…
  • 2013 American Transplant Congress

    Does the Abnormal Result of Implantation Renal Biopsy Affect the Donor Renal Function?

    W. Han, S. Yang, D. Joo, K. Huh, M. Kim, Y. Kim, S. Kim, K. Choi

    Urology, Yonsei University Health System, Urological Science Institute, Seoul, Republic of Korea; Surgery, The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction and Objectives. In this study, we focused on histological abnormalities which found in living kidney donor implantation biopsy (IB) and analyzed with renal function…
  • 2013 American Transplant Congress

    Bone Marrow-Derived Mesenchymal Stem Cells of Neonatal Mice Suppress Dendritic Cells Maturation and T Lymphocyte Proliferation

    X. Dai, X. Li, J. Ma, J. Wang, N. Gong

    Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Background: Mouse bone marrow-derived mesenchymal stem cells (MSCs) cannot be easily harvested in matured mice because of the low MSC frequency, contamination of hematopoietic cells…
  • 2013 American Transplant Congress

    Quantifying Improvement in Donor Travel Safety: Utilization of Centralized Procurement Facilities and outside Surgeon Organ Procurement

    S. Waits, K. Sheetz, W. Kanitz, M. Englesbe

    Department of Surgery, Division of Transplantation, University of Michigan, Ann Arbor, MI

    Intro: Air based organ procurement travel has been noted to be the dangerous. As a 5-year follow-up to the Michigan Donor Travel Forum, we sought…
  • 2013 American Transplant Congress

    Impact of Immunosenescence on Bone Marrow Transplantation (BMT) and Chimerism, The

    K. Hock, R. Oberhuper, Y. Lee, T. Wekerle, S. Tullius

    Department of Surgery, Medical University of Vienna, Vienna, Austria; Division of Transplant Surgery and Transplant Surgery Research Lab, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria

    Background:Tolerance induction through mixed chimerism holds promise for clinical translation but has only been investigated in young recipients. Changing demographics and an accumulation of older…
  • 2013 American Transplant Congress

    Adverse Events of Over-Immunosuppression Are Dependent on Tofacitinib Exposure in Kidney Transplant (KT) Patients

    S. Busque, F. Vincenti, H. Tedesco Silva, P. O'Connell, M. Tortorici, N. Lawendy, W. Wang, G. Chan

    Stanford Univ, Stanford; UCSF, San Francisco; Hosp do Rim e Hipertensao, Sao Paulo, Brazil; Westmead Hosp, Westmead, Australia; Pfizer, Groton

    Background: In a prior Phase 2b study in de novo KT pts, a CNI-free tofacitinib fixed-dose regimen achieved comparable rate of biopsy-proven acute rejection (BPAR),…
  • 2013 American Transplant Congress

    Donor CD4 T Cells Trigger Costimulation Blockade-Resistant Donor Bone Marrow Rejection through Bystander Activation Requiring Interleukin 6

    K. Hock, N. Pilat, U. Baranyi, B. Mahr, C. Klaus, M. Gattringer, T. Wekerle

    Division of Transplantation, Department of Surgery, Medical University of Vienna, Vienna, Austria

    Background:Donor T cells have pleiotropic effects in allogeneic bone marrow transplantation (BMT). Co-transplanting high doses of donor T cells with donor BM causes rejection of…
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