ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Alloantigen-Specific Tregs Can Be Identified by Activation-Induced CD154 Expression

    N. Litjens, C. Baan, M. Betjes

    Internal Medicine, Section Nephrology&Transplantation, Erasmus Medical Center, Rotterdam, Netherlands

    IntroductionAntigen (Ag)-specific T cells can be recognized using cell surface expression of markers specifically induced upon T cell receptor interaction with peptides presented in the…
  • 2013 American Transplant Congress

    CD137, a Marker To Detect the Total Alloreactive T Cell Compartment?

    N. Litjens, E. de Wit, C. Baan, M. Betjes

    Internal Medicine, Section Nephrology&Transplantation, Erasmus Medical Center, Rotterdam, Netherlands

    IntroductionAlloreactive T cells are important mediators of rejection or tolerance of the transplanted organ. Detection and isolation of viable alloreactive T cells at the single…
  • 2013 American Transplant Congress

    Distinct Roles of CD137 and CD137L Bidirectional Signals in Candida albicans Infection

    H. Cho, B. Kwon, J. Lee, V. Tran, J. Chun, S. Park

    Department of Surgery, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea; School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea; Department of Internal Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea; Biomedical Research Center, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea

    Invasive fungal infections by Candida albicans frequently cause mortality in immunocompromised patients, yet the cellular processes leading to this mortality remain ill-defined. Here, using genetic…
  • 2013 American Transplant Congress

    Death on Wating-List and Risk of Transmission of Cancer: Where Is the Right Balance?

    R. Desai, D. Collett, C. Watson, P. Johnson, T. Evans, J. Neuberger

    NHS Blood and Transplant, Bristol, United Kingdom; Addenbrooke's Hospital, Cambridge, United Kingdom; University of Birmingham, Birmingham, United Kingdom; West Midlands Cancer Intelligence Unit, Birmingham, United Kingdom

    Cancer transmission from organ donors is a rare complication of transplantation. While some cancer histories in donors are classed as unacceptable or high risk because…
  • 2013 American Transplant Congress

    Effect of Plasmapheresis on Angiotensin II Type I Receptor Antibody

    H. Eng, R. Montgomery, M. Leffell, A. Zachary

    Immunogenetics Laboratory, Medicine, Johns Hopkins Medical Institutions, Baltimore, MD; Surgery, Johns Hopkins Medical Institutions, Baltimore, MD

    The presence of angiotensin II type I receptor (AT1R) antibody has been associated with renal allograft rejection. We determined the presence of AT1R antibody in…
  • 2013 American Transplant Congress

    Low-Dose Cyclosporine (CsA) Plus Mycophenolate Mofetil (MMF) and Prednisolone (Pred) Triple Immunosuppressive Protocol in Renal Transplantation

    H. Xiang, W. Xue, P. Tian, X. Ding, X. Pan, H. Yan, J. Hou, X. Feng, X. Tian, C. Ding

    Department of Renal Transplant, Center of Nephropathy, The First Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an, China

    BACKGROUND: In order to decrease the rate of adverse effects of cyclosporin, a low-dose CsA plus MMF and Pred triple immunosuppressive protocol was started from…
  • 2013 American Transplant Congress

    Galectin-7 in Cardiac Allografts in Mice: Related to the Acute Rejection and Playng Important Roles in Accelerating Rejection Response

    Z. Luo, Z. Chen

    Institute of Organ Transplantation,Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China

    To survey whether galectin-7 is associated with acute rejection and the function of galectin-7 in acute allograft rejection.In this study, the allografts and isografts were…
  • 2013 American Transplant Congress

    Cumulative Effect of Metabolic Syndrome Components in Predicting Major Adverse Cardiovascular Events after Kidney Transplantation

    G. Prasad, M. Huang, S. Silver, A. Allawati, L. Rapi, M. Nash, J. Zaltzman

    Medicine, University of Toronto, Toronto, ON, Canada; Renal Transplant Program, St. Michael's Hospital, Toronto, ON, Canada

    Background: Metabolic syndrome (MS) refers to a clustering of factors that increases cardiovascular risk. The WHO 1999 definition of MS includes the presence of any…
  • 2013 American Transplant Congress

    Mesenchymal Stem Cell Induced In-Vitro Generation of Regulatory T-Cells – Future Novel Cellular Therapy for Tolerance Induction in Transplantation?

    S. Dave, A. Vanikar, H. Trivedi

    Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, Institute Of Kidney Diseases & Research Centre (IKDRC)- Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India; Department of Nephrology and Transplantation Medicine, Institute Of Kidney Diseases & Research Centre (IKDRC)- Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Ahmedabad, Gujarat, India

    Introduction:Regulatory T-cells (Tregs) have recently been recognized as key players in transplantation immunobiology with little knowledge about their source and dose for tolerance induction.We present…
  • 2013 American Transplant Congress

    Assessing Cell Mediated Immunity (CMI) Status by the ImmuKnow Assay in Renal Transplant Recipients

    H. Xiang, W. Xue, P. Tian, X. Ding, X. Pan, H. Yan, J. Hou, X. Feng, X. Tian, C. Ding

    Department of Renal Transplant, Center of Nephropathy, The First Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an, China

    BACKGROUND: Transplant recipients have a high risk of infection due to overimmunosuppression. However, underimmunosuppression carries with it the risk of rejection. It would be necessary…
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