2013 American Transplant Congress
Transgenic Expression of Human Thrombomodulin in Donor Pigs Reduces the Incidence of Coagulopathies in a Pig to Baboon Cardiac Xenotransplantation Model
Introduction: For cardiac xenograft to become clinical reality, many genetic modifications are required in the donor pigs. We have shown that significant graft survival can…2013 American Transplant Congress
Evaluation of an Immunomodulation Program Utilizing IVIG as a Single Agent vs. Combination Therapy with IVIG and Rituximab
Sensitization in patients on the waiting-list for a kidney transplantation prolongs time to transplant and in some instances, makes transplantation impossible. Previously published experience from…2013 American Transplant Congress
Impact of Implantation of Ventricular Assist Devices on the Incidence of Post-Transplant Infections in Heart Transplant Recipients
CHUV, Lausanne; , Basel; , Bern; , Zurich; , Geneva, Switzerland
Background: Ventricular assist device (VAD) is a valuable option for patients with heart failure awaiting heart transplantation (HTx), although the relatively high incidence of VAD…2013 American Transplant Congress
Increasing Utilization of Older Deceased Donors as an Effective Way To Improve Organ Donation Rates: An International Perspective
In utilizing older or expanded criteria donors (ECD), transplant centers must weigh the benefits of increasing the supply of available organs against the potential risks…2013 American Transplant Congress
High Pre-Transplant Hepatitis B Virus (HBV) Level Predicts HBV Reactivation after Kidney Transplantation in HBV Infected Recipients
Backgrounds: Hepatitis B surface antigen (HBsAg)-positive kidney recipients are at increased risk for mortality and graft failure compared with HBsAg-negative recipients. The aims of this…2013 American Transplant Congress
Screening for Asymptomatic Bacteruria at One Month after Adult Kidney Transplantation: Clinical Factors and Implications
Objective:Urinary tract infections(UTI) are a significant cause of morbidity after kidney transplantation. Screening for asymptomatic bacteruria(AB) has proven beneficial in certain adults like pregnant women;…2013 American Transplant Congress
Establishment of New Methods for Chronic Antibody Mediated Renal Rejection Model with Clinical Immunosuppressive Drugs in Non-Human Primates
Pharmacology Research Labs., Astellas Pharma Inc, Tsukuba, Ibaraki, Japan
BackgroundDespite the improvement of immunosuppressive drugs and therapeutic regimens, long-term renal graft survival is still an unsolved problem. The purpose of this study is to…2013 American Transplant Congress
First in Human Trial of Ischemic Postconditioning in Kidney Transplantation from Donations after Cardiac Death
ObjectiveIschemic postconditioning (IPoC) may reduce renal ischemia-reperfusion injury (IRI) after kidney transplantation (KT). We performed a first human pilot trial to study the feasibility and…2013 American Transplant Congress
Cytomegalovirus and Post-Transplant Cancer: Protection, Predisposition or No Effect?
NHS Blood and Transplant, Bristol, United Kingdom
The role of Cytomegalovirus (CMV) in development of post-transplant de novo cancer is not established. Previous studies have suggested that CMV exposure is associated with…2013 American Transplant Congress
Urinary Transcript Expression Profile in Kidney Transplant Recipients Is Predictive for Post-Transplant Graft Function
There is evidence that non-invasive immunological monitoring may be useful in the early period after renal transplantion, particularly with regard to predicting acute rejection. It…
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