ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Proteasome Inhibition Protects Steatotic Liver Graft through Modulation of the AMPK, Akt and mTOR Pathways

    M. Bejaoui, M. Zaouali, T. Carbonell, F. Bardag-Gorce, E. Pantazi, H. Abdennebi, J. Roselló-Catafau

    Experimental Pathology, Instituto de Investigaciones Biomédicas de Barcelona, CSIC, Barcelona, Spain; Faculty of Biology, Barcelona, Spain; UCLA Medical Center, Torrance, CA; Human Physiology, Faculty of Pharmacy, Monastir, Tunisia

    Background: Hepatic steatosis presents a major challenge in liver transplantation. Steatotic livers show an increased susceptibility to cold ischemia and reperfusion (CIR) injury. The mechanisms…
  • 2013 American Transplant Congress

    Critical Analysis of Death within 1 Year after Liver Transplantation, A

    A. Rana, M. Porubsky, T. Jie, S. Habib, H. Rilo, B. Kaplan, A. Gruessner, R. Gruessner

    Abdominal Transplnatation, University of Arizona, Tucson

    Context: In the current era, 15% of liver transplant recipients die within the first year. While this may be viewed as a feat in comparison…
  • 2013 American Transplant Congress

    Impact of Recipient Body Mass Index in Short and Long Term Survival of Pancreatic Grafts

    B. Bédat, N. Niclauss, A. Andres, A. Jannot, C. Toso, P. Morel, T. Berney

    Division of Visceral and Transplantation Surgery, University Hospitals of Geneva, Geneva, Switzerland; Division of Clinical Epidemiology, University Hospitals of Geneva, Geneva, Switzerland

    Background: In pancreas transplantation, the impact of recipient BMI on short and long term pancreas graft survival has not been studied.Methods: We analyzed data from…
  • 2013 American Transplant Congress

    Prevalence and Predictive Factors of Early Cardiovascular Events after Kidney Transplantation: Which Screening Strategy?

    M. Delville, L. Sabbah, D. Girard, C. Elié, F. Martinez, A. Méjean, C. Legendre, R. Sberro-Soussan

    Transplantation Rénael Adulte, APHP Hopital Necker Enfant Malade, Paris, France

    Cardiovacular diseases are the first cause of mortality after renal transplantation. The purpose of this study was to analyze early cardiovascular events occurrence after kidney…
  • 2013 American Transplant Congress

    Decline in Living Kidney Donation in the United States: Random Variation or Cause for Concern?, The

    J. Rodrigue, J. Schold, D. Mandelbrot

    The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

    In the United States, the decline in living kidney donation over the last several years is indisputable. Since the peak in 2004 living kidney donation…
  • 2013 American Transplant Congress

    Treg Require Th1 and Th2 Transcription Factors To Prolong Islet Allograft Survival

    D. Iwami, J. Bromberg

    University of Maryland, Baltimore, MD

    Introduction: Transcription factors essential for pathogenic Th1 and Th2 development have been shown to regulate some aspects of Treg functions during inflammation and autoimmunity. We…
  • 2013 American Transplant Congress

    Detection of Anti-HLA Class I but Not C1q-Fixing Donor-Specific Antibodies before Kidney Transplantation Predicts Early Graft Loss

    M. Crespo, A. Torío, V. Mas, M. Perez-Saez, M. Mir, A. Faura, M. Checa, J. Pascual

    Nephrology, Hospital del Mar, Barcelona, Spain; Immunology and Nephrology, Hospital Insular, Las Palmas, Spain; Immunology, Laboratori Referencia Catalunya, Hospital del Mar, Barcelonaq, Spain

    Anti-HLA donor-specific antibodies(DSA) identified by Luminex are questioned for excess in sensitivity and lack of prediction of clinical events after kidney transplantation(KT). We performed a…
  • 2013 American Transplant Congress

    Restoration of Long Nerve Defects with Epineural Sheath Conduit Supported with Bone Marrow Stromal Cells. A Preliminary Report

    M. Madajka, C. Ozturk, M. Lukaszuk, G. Kwiecien, J. Szopinski, V. Siemionow, M. Siemionow

    Plastic Surgery, Cleveland Clinic, Cleveland, OH; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH

    Hypothesis: Nerve gaps that need conduit or allograft material tend to involve a gap of over 20 cm. The present standard of care is autograft…
  • 2013 American Transplant Congress

    Polyclonal Light Chain Deposition in the Proximal Tubules Early after Deceased Donor Renal Transplantation: A Contributing Factor for Graft Dysfunction?

    R. Parasuraman, A. Koffron, V. Mudunuri, S. Cohn, V. Raofi, L. Rocher, M. Gabriel, S. Dilip, P. Zhang

    Division of Transplantation, Beaumont Health System, Royal Oak, MI; Anatomic Pathology, Beaumont Health System, Royal Oak, MI

    Introduction: Delayed or Slow graft function (GD) immediately after deceased donor renal transplant (DDRTX) is often multifactorial in etiology with ischemia-reperfusion and immunological injury being…
  • 2013 American Transplant Congress

    Extended-Release Tacrolimus Plus Everolimus vs Extended-Release Tacrolimus Plus Micophenolate Mofetil in Primary Deceased Donor Kidney Transplant Recipients: 1-Year Results of an Open Label, Randomized Phase 2 Clinical Trial

    E. Favi, N. Silvestrini, J. Pedroso, M. Salerno, G. Spagnoletti, V. Bianchi, J. Romagnoli, F. Citterio

    Surgery - Renal Transplantation, Catholic University, Rome, Italy

    Purpose. Aim of this randomized phase 2 trial in kidney transplantation was to compare an immunosuppressive regimen based on the association of low-dose ER-tacrolimus and…
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