ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Importance of MDR1 Gene Polymorphisms for Calcineurin Inhibitors Dosage and Early Kidney Graft Function, The

    M. Kravljaca, V. Pravica, E. Savic, V. Brkovic, V. Lezaic, R. Naumovic

    Clinic of Nephrology, Clinical Center of Serbia, Belgrade, Serbia; Institute of Microbiology and Immunology, School of Medicine, University of Belgrade, Belgrade, Serbia; School of Medicine, University of Belgrade, Belgrade, Serbia

    Calcineurin inhibitors (CNIs) are a substrate of P-glycoprotein, the product of the multidrug resistance (MDR1) gene and has been known to undergo extensive hepatic metabolism…
  • 2013 American Transplant Congress

    Older Living Donor Kidney Transplantation vs. Dialysis on the Waiting List and Standard Criteria Deceased Donor Kidney Transplantation: A Decision Analysis

    R. Sapir-Pichhadze, F. Farrokhi, N. David, F. Rob, J. Kim

    Medicine, University of Toronto, Toronto, ON, Canada

    Background: Living donor (LD) kidney transplantation provides improved outcomes compared with deceased donor (DD) kidney transplantation. Little is known about health gains associated with older…
  • 2013 American Transplant Congress

    Amnion-Derived Multipotent Progenitor Cells Support Allograft Tolerance Induction

    K. Anam, Y. Lazdun, P. Davis, R. Banas, E. Elster, T. Davis

    Regenerative Medicine Department, Navy Medical Redearch Center, Silver Spring, MD; Stemnion Inc, , Pittsburgh, PA

    Donor-specific immunological tolerance using high doses of donor bone marrow cells (BMC) has been demonstrated in mixed chimerism-based tolerance induction protocols; however, the development of…
  • 2013 American Transplant Congress

    Prevalence and Predictive Factors of Early Cardiovascular Events after Kidney Transplantation: Which Screening Strategy?

    M. Delville, L. Sabbah, D. Girard, C. Elié, F. Martinez, A. Méjean, C. Legendre, R. Sberro-Soussan

    Transplantation Rénael Adulte, APHP Hopital Necker Enfant Malade, Paris, France

    Cardiovacular diseases are the first cause of mortality after renal transplantation. The purpose of this study was to analyze early cardiovascular events occurrence after kidney…
  • 2013 American Transplant Congress

    Decline in Living Kidney Donation in the United States: Random Variation or Cause for Concern?, The

    J. Rodrigue, J. Schold, D. Mandelbrot

    The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

    In the United States, the decline in living kidney donation over the last several years is indisputable. Since the peak in 2004 living kidney donation…
  • 2013 American Transplant Congress

    Treg Require Th1 and Th2 Transcription Factors To Prolong Islet Allograft Survival

    D. Iwami, J. Bromberg

    University of Maryland, Baltimore, MD

    Introduction: Transcription factors essential for pathogenic Th1 and Th2 development have been shown to regulate some aspects of Treg functions during inflammation and autoimmunity. We…
  • 2013 American Transplant Congress

    Detection of Anti-HLA Class I but Not C1q-Fixing Donor-Specific Antibodies before Kidney Transplantation Predicts Early Graft Loss

    M. Crespo, A. Torío, V. Mas, M. Perez-Saez, M. Mir, A. Faura, M. Checa, J. Pascual

    Nephrology, Hospital del Mar, Barcelona, Spain; Immunology and Nephrology, Hospital Insular, Las Palmas, Spain; Immunology, Laboratori Referencia Catalunya, Hospital del Mar, Barcelonaq, Spain

    Anti-HLA donor-specific antibodies(DSA) identified by Luminex are questioned for excess in sensitivity and lack of prediction of clinical events after kidney transplantation(KT). We performed a…
  • 2013 American Transplant Congress

    Restoration of Long Nerve Defects with Epineural Sheath Conduit Supported with Bone Marrow Stromal Cells. A Preliminary Report

    M. Madajka, C. Ozturk, M. Lukaszuk, G. Kwiecien, J. Szopinski, V. Siemionow, M. Siemionow

    Plastic Surgery, Cleveland Clinic, Cleveland, OH; Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH

    Hypothesis: Nerve gaps that need conduit or allograft material tend to involve a gap of over 20 cm. The present standard of care is autograft…
  • 2013 American Transplant Congress

    Polyclonal Light Chain Deposition in the Proximal Tubules Early after Deceased Donor Renal Transplantation: A Contributing Factor for Graft Dysfunction?

    R. Parasuraman, A. Koffron, V. Mudunuri, S. Cohn, V. Raofi, L. Rocher, M. Gabriel, S. Dilip, P. Zhang

    Division of Transplantation, Beaumont Health System, Royal Oak, MI; Anatomic Pathology, Beaumont Health System, Royal Oak, MI

    Introduction: Delayed or Slow graft function (GD) immediately after deceased donor renal transplant (DDRTX) is often multifactorial in etiology with ischemia-reperfusion and immunological injury being…
  • 2013 American Transplant Congress

    Extended-Release Tacrolimus Plus Everolimus vs Extended-Release Tacrolimus Plus Micophenolate Mofetil in Primary Deceased Donor Kidney Transplant Recipients: 1-Year Results of an Open Label, Randomized Phase 2 Clinical Trial

    E. Favi, N. Silvestrini, J. Pedroso, M. Salerno, G. Spagnoletti, V. Bianchi, J. Romagnoli, F. Citterio

    Surgery - Renal Transplantation, Catholic University, Rome, Italy

    Purpose. Aim of this randomized phase 2 trial in kidney transplantation was to compare an immunosuppressive regimen based on the association of low-dose ER-tacrolimus and…
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