ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Lipocalin-2 in Serum Samples of Recipients Following Liver Transplantation as Predictive and Monitoring Marker for Acute Allograft Rejection

    N. Vallant, H. Maier, M. Kofler, P. Schumpp, S. Schneeberger, R. Oellinger, J. Pratschke, F. Aigner

    Department of Visceral,- Thoracic- and Transplant Surgery, Medical University, Innsbruck, Tyrol, Austria

    PURPOSE: Lipocalin-2 (Lcn-2) has been described as a marker and modulator of inflammation during ischemia/reperfusion injury (IRI) following solid organ transplantation. Aim of this study…
  • 2013 American Transplant Congress

    Early Look at the OPTN Explant Pathology Form Data, An

    A. Harper, E. Edwards, J. Heimbach, R. Hirose, R. Freeman, K. Olthoff

    Uniited Network for Organ Sharing, Research, Richmond, VA; Surgery, Mayo Clinic, Rochester, MN; Surgery, UCSF Medical Center, San Francisco, CA; Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH; Surgery, The Hosp of the Univ of Pennsylvania, Phildelphia, PA

    Background: Candidates with exceptions for hepatocellular carcinoma (HCC) accounted for 29% of liver transplants during the first 6 months of 2012. OPTN policy requires submission…
  • 2013 American Transplant Congress

    Correlation of Global Copy Number Changes with Micro RNA Expression Profiling Reveals MUC1 as a Marker for HCC Recurrence after Transplant

    C. Barry, C. Whitney-Miller, M. Orloff

    Transplant Surgery, University of Rochester, Rochester, NY; Pathology, University of Rochester, Rochester, NY

    INTRODUCTION: Epigenetic changes are known to play a pivotal role in hepatocellular carcinogenesis, but the effects of these changes on cancer cell protein expression remain…
  • 2013 American Transplant Congress

    Exogenous Hydrogen Sulphide Mitigates Long-Term Renal Dysfunction Associated with Warm Renal Ischemia-Reperfusion Injury

    J. Zhu, I. Lobb, W. Liu, B. Garcia, Z. Lan, A. Sener

    Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada

    Background:The incidence of renal cell carcinoma (RCC) is concurrently rising with increased prevalence of end-stage renal disease (ESRD) world-wide. Treatment for RCC is limited and…
  • 2013 American Transplant Congress

    Retransplantation with or without Graft Nephrectomy. A Single Centre Experience

    C. Puliatti, E. Giorgakis, A. Syed

    Renal Transplantation, Royal London Hospital, London, United Kingdom

    Introduction:This study aims to review the impact of nephrectomy of a failed primary allograft on the graft survival of renal retransplantation.Material/Method:This is a retrospective study…
  • 2013 American Transplant Congress

    Super Regions Can Reduce Geographic Disparities in Liver Transplantation

    A. Rana, M. Porubsky, T. Jie, S. Habib, H. Rilo, B. Kaplan, A. Gruessner, R. Gruessner

    Abdominal Transplantation, University of Arizona, Tucson

    Context: The significant geographic disparities in liver transplantation have been a point of contention in the transplant community. In the attempt to establish greater equity,…
  • 2013 American Transplant Congress

    RIP3 Mediated Necroptosis Regulates Cardiac Allograft Inflammation and Survival

    A. Pavlosky, X. Huang, A. Lau, Z. Yin, A. Haig, A. Jevnikar, Z. Zhang

    Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; Medicine, Western University, London, ON, Canada; Pathology, Western University, London, ON, Canada

    Despite recent advances in immunosuppression, patients who have undergone allogeneic cardiac transplantation still suffer from poorly understood chronic graft loss. Previous studies have shown that…
  • 2013 American Transplant Congress

    Promising Outcomes after Long-Term Therapy with Everolimus in Kidney Transplant Patients: Two-Years Results of the CERTIC Registry

    M. Carmellini, S. Federico, P. Messa, G. Gubbiotti, M. Salvadori, D. Colombo, R. Brusa, C. Ponticelli

    AOU Senese - Policlinico Santa Maria alle Scotte, Siena, Italy; AOU Policlinico Federico II - Università degli Studi, Napoli, Italy; Fondazione Ospedale Maggiore Policlinico, Milano, Italy; AO - Ospedale Santa Maria della Misericordia, Perugia, Italy; AOU Careggi - Villa Monna Tessa, Firenze, Italy; Novartis Farma, Origgio (VA), Italy; Humanitas Institute, Milano, Italy

    Everolimus, a mammalian target of rapamycin (mTOR) inhibitor, is licensed for the prevention of acute rejection in heart or kidney transplant recipients. Based on the…
  • 2013 American Transplant Congress

    Everolimus Facilitated Reduction of Tacrolimus in De Novo Liver Transplant Recipients: 12-24 Month Data from North America

    W. Chapman, R. Brown Jr, D. Sudan, K. Chavin, B. Koneru, M. Huang, G. Junge, J. Hexham, G. Dong, A. Wiland, J. Fung

    Washington Univ School of Medicine, St Louis, MO; Columbia Univ Medical Center, New York, NY; Duke Univ Medical Center, Durham, NC; Medical Univ of SC, Charleston, SC; Univ of Medicine and Denstistry-NJ Medical School, Newark, NJ; Henry Ford Hosp, Detroit, MI; Novartis AG, Basel, Switzerland; Novartis Pharmaceuticals Corporation, East Hanover, NJ; Cleveland Clinic, Cleveland, OH

    Purpose: In Study H2304, everolimus (EVR) facilitated early tacrolimus (TAC) minimization with comparable efficacy and better renal function vs standard TAC at 12 months (M)…
  • 2013 American Transplant Congress

    Evolving Trends in Living Donor Uninephrectomy Techniques and Impact on Post-Transplant Outcomes: A Review of the US National Cohort

    J. Verbesey, M. Grafals, M. Cooper, J. Moore, S. Ghasemian, C. Nilubol, B. Javaid

    MedStar Georgetown Transplant Institute, Washington, DC

    Background: In the US majority of living donor uninephrectomy procedures for kidney transplantation are currently done by laparoscopic techniques. We wanted to assess the variations…
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