2013 American Transplant Congress
IL-21R+ Marginal Zone Precursor (MZP) B Cells in the Germinal Center Induce IL-10 Dependent Allogeneic Tolerance
National Centre for Cell Science, Pune, MH, India; University of Maryland, Baltimore, MD
Background: B cells have regulatory functions and promote tolerance by inducing deletion or anergy of CD8+ T cells, increasing Foxp3+Treg, inhibiting proliferation of CD4 T…2013 American Transplant Congress
Donor-Derived Semimature Dendritic Cells Transfusion Inducing Tolerance in Acute Rejection of Rat Liver Transplantation
Background and Objective: We recently found that donor semimature dendritic cells (smDCs) could promote skin allograft survival in mice by activating host antigen-specific CD4+CD25+Foxp3+T-regulatory cells…2013 American Transplant Congress
Net Time-Dependent ROC Curves: A New Method for Evaluating the Accuracy of a Marker To Predict Mortality Related to End-Stage Renal Disease in Kidney Transplant Recipients
Identifying prognostic markers of mortality in transplantation is essential for determining patients at high-risk of death and optimizing medical management. Nevertheless, an important part of…2013 American Transplant Congress
IL-1β Polymorphism Increase Susceptibility to Invasive Mold Infection after Solid Organ Transplantation (SOT)
Background Polymorphisms in innate immune genes such as pattern recognition receptors (TLR1, TLR4, Dectin-1), cytokines (TNF-Α, IL-1Β) or other molecules (CARD9, Β-defensin1 [DEFB1]) were previously…2013 American Transplant Congress
Induced Pluripotent Stem Cells from Familial Amyloidotic Polyneuropathy Patients
Backgroud: Familial amyloidotic polyneuropathy (FAP) is an autosomal-dominant hereditary systemic amyloidosis induced by amyloidogenic transthyretin (ATTR). Because most transthyretin (TTR) in serum is synthesized by…2013 American Transplant Congress
Intravital Two-Photon Imaging of Neutrophil Recruitment Reveals an Efficacy of FPR1 Blockade To Attenuate the Hepatic Ischemia-Reperfusion Injury
Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan
Background: Evidence is accumulating that formyl-peptide receptor (FPR) signaling constitutes an important danger signal that guide neutrophils to sites of inflammation. This study aimed to…2013 American Transplant Congress
Surviving B Cells in Different Lymphoid Organs after Rituximab Administration and Its Association with Clinical Outcomes
Urology, Akita University Graduate School of Medicine, Akita, Japan
BackgroundRituximab (RIT), anti-CD20 antibody, has been applied to kidney transplantation because of its potent B-cell depleting effect. Although CD20+ cells in peripheral blood (PB) and…2013 American Transplant Congress
Multistate Model To Investigate the Relationship between Pre-Graft Level of Angiotensin II Type 1 Receptor (AT1R) Antibodies and Kidney Transplant Recipients Outcome, A
Antibodies reactive with non-HLA target-angiotensin II type 1 receptor (AT1R) have been found during acute rejection with vascular involvement in kidney transplants recipients (KTR). We…2013 American Transplant Congress
Acute Rejection Is Associated with Increased Microvascular Tortuosity and a Dysbalance in Angiopoietins up to 1 Year after Rejection
Well-functioning endothelium is critical for a healthy graft after solid organ transplantation. In the context of transplantation, microvascular endothelial cells (ECs) are very susceptible to…2013 American Transplant Congress
Liver Transplantation Versus Liver Resection in the Treatment of Hepatocellular Carcinoma: A Meta-Analysis
Objective: To systematically evaluate the clinical outcomes of HCC patients undergoing LT and LR.Methods: A search of PubMed/Medline, Embase and Cochrane library databases was supplemented…
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