2013 American Transplant Congress
Balance between Interleukin 17-Secreting T Helper Cells and Regulatory T Cells after Renal Transplantation: Relation to Graft Function and Survival, The
Background: Repeated attacks of acute rejection can result in chronic allograft dysfunction (CAD) which is the most prevalent cause of graft loss. T helper (Th)…2013 American Transplant Congress
Liver Transportation Time Model and Comparison with Cold Ischemia Time
Background: Prolonged cold ischemia time (CIT) is associated with worse outcomes after deceased donor liver transplant. One factor influencing CIT is transport time, the time…2013 American Transplant Congress
Disappearance of Immunoglobulin Producing Plasmablasts in Kidney Transplant Patients Is Associated with a Diminished Cytokine Producing Capacity by Peripheral Follicular T-Lymphocytes
Internal Medicin & Transplant Immunology, Erasmus MC, Rotterdam, South-Holland, Netherlands
BACKGROUND Follicular T-helper cells (Thf-cells) play a pivotal role in the differentiation of B-cells into Ig secreting cells, i.e. plasmablasts. CD4+CXCR5+ T-cells are their peripheral…2013 American Transplant Congress
Population Pharmacokinetics of Voclosporin: Body Surface Area Optimized Dosing
Objective:To determine the population pharmacokinetics (popPK) of voclosporin (VCS), a new calcineurin inhibitor (CNi), and explore potential covariate relationships to individualize drug dosing.Background:Inter and intra-individual…2013 American Transplant Congress
E-Cad Promotes Liver Tissue Formation in Hepatic Differentiation of Mouse Embryonic Stem Cells through Regulating the Differentiation Progress
Objective Until now, the hepatic differentiation of embryonic stem cells (ESCs) usually results in single cell lineage and could not form liver tissues. In this…2013 American Transplant Congress
Effects of High Fat Breakfast, Low Fat Breakfast or Fasting on the Absorption of Voclosporin (VCS), The
Isotechnika Pharma Inc., Edmonton, Canada
Objective:To assess the effects of fasting, consumption of a high-fat breakfast and consumption of a low-fat breakfast on the absorption of VCS, a new calcineurin…2013 American Transplant Congress
Late Extra-Hepatic Biliary Strictures after Liver Transplantation: First Evidence of Association with Pre-Existing Donor Specific Antibodies
Late biliary strictures following liver transplantation are a major source of graft loss, and usually attributed to vascular problems. In many cases, however, vascular pathologies…2013 American Transplant Congress
Mesenchymal Stromal Cells Promote Bowel Regeneration after Intestinal Transplantation: Myth to Mucosa
Aim: To report the first case of use of mesenchymal stromal cells (MSCs) to promote mucosal regeneration in an isolated intestinal transplant recipient who had…2013 American Transplant Congress
CCR2 Dependent Migration Is Absolutely Required for Myeloid Suppressor Cells To Protect Cell Transplants
Whole organ transplantation gets great success, while the outcomes of cell transplants remain poor, suggesting a critical role of non-parenchymal cells in immune regulation. Through…2013 American Transplant Congress
Kidney Transplantation: Pre and Post-Transplant Immunological Evaluation and Outcome of Recipients in Low, Medium, and High Risk of Rejection
Specific antibodies (AB) against donor (DSA) have a fundamental role in the mechanism of kidney (K) transplant rejection and represent one of the main barriers…
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