ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Impact of Anatomical Variations and Insufficient Liver Volume on Living Liver Donation, The

    W. Al-hamoudi, N. Allam, H. Elsiesy, A. Hashim, B. Hegab, Y. El-Sheikh, M. Al-sofayan, H. Albahili, D. Broering, M. Al sebayel, F. Abaalkhail

    King Saud University, Riyadh, Saudi Arabia; Liver Transplantatiom, King Faisal Specialist Hospital, Riyadh, Saudi Arabia

    Background and Aims: Organ shortage has been the ongoing obstacle to expand liver transplantation world-wide including Saudi Arabia. Living donor liver transplantation (LDLT) was hoped…
  • 2013 American Transplant Congress

    Project NOTIFY: A Global Database of Serious Adverse Events and Reactions in Organs, Tissues, and Cells

    M. Ison, D. Strong, D. Fehily, E. Chatzixiros, A. Costa, L. Noel

    Divisions of Infectious Diseases & Organ Transplantation, Northwestern University, Chicago; Orthopaedics and Sports Medicine, University of Washington, Seattle; National Transplant Center (CNT), Rome, Italy; Department of Essential Health Technologies, World Health Organization, Geneva, Switzerland

    Background: Serious adverse reactions and events (SAREs) are a threat to the safety and outcome of transplantation. World Health Assembly Resolution WHA 63.22 urges Member…
  • 2013 American Transplant Congress

    Pharmacokinetics of Voclosporin (VCS) in Renal Impairment, The

    L. Aspeslet, D. Freitag, R. Huizinga, P. Mayo, S. Ling, R. Foster

    Isotechnika Pharma Inc, Edmonton, Canada

    Objective:To determine the pharmacokinetic profile of VCS in subjects with renal impairment.Methods:VCS 0.4 mg/kg was administered to subjects with Normal, Mild, Moderate, or Severe renal…
  • 2013 American Transplant Congress

    Intrahepatic Cholangiocarcinoma (I-CC) or Mixed Hepatocellular-Cholangiocarcinoma (HCC-CC) in Patients Undergoing Liver Transplantation (LT). A Spanish Case Control Multicenter Study

    R. Charco, G. Sapisochin, C. Rodriguez-Lope, M. Gastaca, J. Ortiz de Urbina, R. Lopez-Andujar, F. Palacios, E. Ramos, J. Fabregat, J. Castroagudin, E. Varo, J. Pons, P. Parrilla, M. Gonzalez-Dieguez, M. Rodriguez, A. Otero, M. Vazquez, G. Zozaya, J. Herrero, G. Sanchez Antolin, B. Perez, R. Ciria, S. Rufián, Y. Fundora, J. Ferrón, A. Guiberteau, G. Blanco, M. Varona, M. Barrera, M. Suarez, J. Santoyo, J. Bruix

    Hosital Universitario Vall d'Hebron, Barcelona, Spain; Hospital Clinic, University of Barcelona, IDIBAPS, Barcelona, Spain; Hospital Universitario de Cruces. Universidad del Pais Vasco, Bilbao, Spain; Hospital Universitario La Fe, Valencia, Spain; Hospital Universitraio de Bellvitge, L'Hospitalet de Llobregat, Spain; Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain; Hospital Virgen de la Arrixaca, Murcia, Spain; Hospital Central de Asturias, Oviedo, Spain; Hospital Universitario de A Coruña, La Coruña, Spain; Clinica Universitaria de Navarra, Pamplona, Spain; Hospital Rio Hortega, Valladolid, Spain; Hospital Universitario Reina Sofia, Córdoba, Spain; Hospital Universitraio Virgen de las Nieves, Granada, Spain; Hospital Universitario Infanta Cristina, Badajoz, Spain; Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain ; Hospital Carlos Haya, Malaga, Spain

    Aim: to evaluate the outcome of patients with HCC-CC or I-CC at explant pathology after LT for suspected HCC.Methods:A case-control study 1:2. Study group(n=42) formed…
  • 2013 American Transplant Congress

    Flow Is Critical for Maintaining a Protective Phenotype in Renal Proximal Tubular Cells

    M. Timsit, W. Adams, A. Laguna-Fernandez, T. Ichimura, J. Bonventre, G. Garcia-Cardena, S. Tullius

    Transplant Surgery Research Lab, Harvard Medical School, Brigham and Women's Hospital, Boston, MA; Laboratory for Systems Biology, Center for Excellence in Vascular Biology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA; Renal Division, Harvard Medical School, Brigham and Women's Hospital, Boston, MA; Université Paris Descartes, Sorbonne Paris Cité, Paris, France

    Background. The impact of flow cessation on proximal tubular cell homeostasis and glomerulotubular balance is of clinical significance during renal ischemia and organ preservation. Consequences…
  • 2013 American Transplant Congress

    Pre-Transplant Immediately Early-1-Specific T-Cell Responses Provides Protection for CMV Infection after Kidney Transplantation

    O. Bestard, M. Lucia, E. Crespo, J. Cruzado, D. Palacio, E. Melilli, J. Torras, S. Gil-Vernet, J. Grinyó

    Renal Transplant Unit, Nephrology Department, Bellvitge University Hospital, Barcelona, Spain; Experimental Nephrology Department, IDIBELL, Barcelona, Spain; Nefrology Department, Hospital San Vicente de Paul, Bogota, Colombia

    Human cytomegalovirus (CMV) infection is still a major complication after kidney transplantation. Although it is well known that cytotoxic CMV-specific CD8+ T cells play a…
  • 2013 American Transplant Congress

    Hypothermic Machine Perfusion To Optimise the Timing of Renal Transplantation

    A. Guy, M. Field, H. Krishnan, N. Inston, A. Ready

    Renal Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, West Midlands, United Kingdom

    BackgroundConflict has always existed between Cold Ischaemic Time (CIT) and safe, timely transplantation. Keeping CIT short may entail operating on complex patients with considerable co-morbidity…
  • 2013 American Transplant Congress

    Soluble BAFF Levels Correlate with De Novo DSA Development and Progression to Chronic Active Antibody-Mediated Rejection in Pediatric Recipients of First Kidney Transplants

    P. Comoli, G. Quartuccio, M. Cioni, A. Parodi, I. Fontana, S. Basso, A. Magnasco, A. Tagliamacco, A. Nocera, M. Cardillo, F. Ginevri

    Pediatric Hematology/Oncology, IRCCS Fondazione S. Matteo, Pavia, Italy; Pediatric Nephrology, G. Gaslini Institute, Genova, Italy; Department of Surgery, IRCCS San Martino, Genova, Italy; Transplantation Immunology, Fondazione Cà Granda Ospedale Maggiore Policlinico, Milano, Italy

    De novo donor-specific antibody (dnDSA) development is associated with late/chronic active antibody-mediated rejection (CAMR) and graft failure in low-risk kidney recipients. It has been recently…
  • 2013 American Transplant Congress

    Effects of Hepatic Impairment on Single and Multiple Oral Dose Pharmacokinetics of Voclosporin (VCS)

    L. Aspeslet, D. Freitag, R. Huizinga, P. Mayo, S. Ling, R. Foster

    Isotechnika Pharma Inc, Edmonton, AB, Canada

    Objective:To determine the pharmacokinetic profile of VCS in subjects with hepatic impairment after single or multiple doses.Methods:VCS 0.4 mg/kg was administered to subjects with hepatic…
  • 2013 American Transplant Congress

    Simple Cardiovascular Risk Score Predicts Mortality in Kidney Transplant Candidates, A

    C. Lawrence, S. Cruickshank, A. Manoj, S. Mathavakkannan, S. Chandna, S. Fluck, K. Farrington

    Renal Unit, Lister Hospital, Stevenage, United Kingdom

    For patients with renal failure kidney transplantation (KTx) confers improved quality and length of life. The survival benefit from KTx is limited by death from…
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