2013 American Transplant Congress
Epithelial-to-Mesenchymal Transition and Tacrolimus Toxicity in Renal Transplant Recipient
IntroductionAnticalcineurins long-term use is associated with interstitial fibrosis, partly responsible for chronic graft dysfunction in kidney transplantation. Studies in patients treated with cyclosporine show that…2013 American Transplant Congress
Low-Molecular-Weight Heparin Dosing and Monitoring in Solid Organ Transplant Recipients
Anti-Xa monitoring for low-molecular-weight heparin (LMWH) is currently recommended in obese, renally impaired, and pregnant patients. Substantial evidence indicates solid organ transplant (SOT) patients are…2013 American Transplant Congress
Hypothermic Machine Perfusion To Optimise the Timing of Renal Transplantation
BackgroundConflict has always existed between Cold Ischaemic Time (CIT) and safe, timely transplantation. Keeping CIT short may entail operating on complex patients with considerable co-morbidity…2013 American Transplant Congress
Soluble BAFF Levels Correlate with De Novo DSA Development and Progression to Chronic Active Antibody-Mediated Rejection in Pediatric Recipients of First Kidney Transplants
De novo donor-specific antibody (dnDSA) development is associated with late/chronic active antibody-mediated rejection (CAMR) and graft failure in low-risk kidney recipients. It has been recently…2013 American Transplant Congress
Effects of Hepatic Impairment on Single and Multiple Oral Dose Pharmacokinetics of Voclosporin (VCS)
Isotechnika Pharma Inc, Edmonton, AB, Canada
Objective:To determine the pharmacokinetic profile of VCS in subjects with hepatic impairment after single or multiple doses.Methods:VCS 0.4 mg/kg was administered to subjects with hepatic…2013 American Transplant Congress
Simple Cardiovascular Risk Score Predicts Mortality in Kidney Transplant Candidates, A
Renal Unit, Lister Hospital, Stevenage, United Kingdom
For patients with renal failure kidney transplantation (KTx) confers improved quality and length of life. The survival benefit from KTx is limited by death from…2013 American Transplant Congress
Dual Kidney Transplants from Marginal Donors: Double or Nothing
Surgery, Wake Forest School of Medicine, Winston Salem, NC
The purpose of this study was to review retrospectively our single center experience with adult dual kidney transplants (DKT) from marginal donors with limited nephron…2013 American Transplant Congress
Concomitant Azathioprine and Warfarin Warrants Significant Warfarin Dosage Increase
Barnes-Jewish Hospital, St. Louis, MO
Purpose: The concomitant use of azathioprine (AZA) and warfarin (WAR) occurs commonly in solid organ transplant (SOT) recipients. Case reports in non-SOT patients have suggested…2013 American Transplant Congress
Liver Allografts Do Not Always Protect from Kidney Allograft Rejection in Sensitized Recipients of Simultaneous Liver-Kidney Transplants
Objectives: To determine the impact of pre-existing and de novo circulating anti-HLA antibodies (DSA or not, in simultaneous liver-kidney transplants (SLKT).Methods: Thirty-nine adult recipients underwent…2013 American Transplant Congress
Coronary Angiography in Asymptomatic Kidney Transplant Candidates?
Renal Unit, Lister Hospital, Stevenage, United Kingdom
Patients with end stage renal failure are at high risk of coronary artery disease (CAD). In transplant patients death with function due to cardiovascular disease…
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