ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Germinal Centre Responses Drive Epitope Diversification in an Autoantibody-Mediated Model of Heart Allograft Vasculopathy

    M. Qureshi, T. Conlon, R. Motallebzadeh, I. Harper, E. Bolton, J. Bradley, G. Pettigrew

    Surgery, University of Cambridge, Cambridge, United Kingdom

    IntroductionAutoantibody following organ transplantation is increasingly correlated with poor graft outcome.We have reported recently that in a MHC class II mismatched mouse heart transplant model,graft-versus-host…
  • 2013 American Transplant Congress

    Boceprevir-Based Tritherapy of HCV-Infected Belgian Liver Transplanted Patients: Preliminary Experience

    D. Degré, I. Colle, H. Van Vlierberghe, C. Moreno

    Department of Gastroenterology Hepatopancreatology and Digestive Oncology, Erasme Hospital Université Libre de Bruxelles, Brussels, Belgium; Department of Hepatogastroenterology, Ghent University Hospital, Ghent, Belgium

    Background: Management of recurrent hepatitis C infection remains a major challenge after liver transplantation. Protease-inhibitor based regimens improve virological response in non-transplanted HCV genotype 1…
  • 2013 American Transplant Congress

    Establishment of Limited Sampling Strategy for the Estimation of Once-Daily Extended-Release Formulation of Tacrolimus Exposure in Adult Kidney Transplant Recipients

    H. Harada, K. Achiwa, N. Fukuzawa, Y. Yuki, K. Hotta, T. Seki, M. Togashi

    Kidney Transplant and Urologic Surgery, Sapporo City General Hospital, Sapporo, Hokkaido, Japan; Pharmacy, Sapporo City General Hospital, Sapporo, Hokkaido, Japan

    INTRODUCTION: Once-daily extended-release formulation of tacrolimus (QD-TAC) is expected to provide equal effects to the twice-daily formulation of tacrolimus with better drug adherence. As a…
  • 2013 American Transplant Congress

    Prognostic Significance of Changes in Proteinuria in Early Stages of Renal Transplantation

    A. Sancho Calabuig, E. Gavela Martínez, J. Kanter Berga, B. Vizcaíno, S. Beltrán, L. Pallardó Mateu

    Nephrology, Hospital Universitari Dr Peset, Valencia, Spain

    Proteinuria is highly prevalent in renal transplantation, but there is no information about the relationship between changes in proteinuria in early stages of transplantation and…
  • 2013 American Transplant Congress

    Efficacy and Safety of Prolonged Valganciclovir Prophylaxis in Children after Living Donor Liver Transplantation

    T. Ueno, S. Ibuka, K. Masahata, M. Nomura, K. Nara, S. Uehara, H. Soh, T. Oue, H. Kondou, N. Usui

    Pediatric Surgery, Osaka University, Suita, Japan; Pediatrics, Osaka University, Suita, Japan

    Introduction: Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are the most common viral infections after solid organ transplantation. Especially in pediatric patients, primary infection may…
  • 2013 American Transplant Congress

    Safety of Telaprevir and Its Effect on the Pharmacokinetics of Tacrolimus in the Treatment of Hepatitis C after Liver Transplantation, The

    N. Alkhouri, J. Bollinger, G. Singh, D. Issa, W. Carey, J. Fung, N. Zein, B. Eghtesad

    Digestive Disease Institute, Cleveland Clinic, Cleveland, OH

    Limited data are available on using telaprevir (TVR)-based triple therapy to treat HCV recurrence post-liver transplantation (LTx). We report our experience on the effects of…
  • 2013 American Transplant Congress

    Anti HLA Immunisation Related to Skin Allograft in Extensively Burned Patients: Assessment in Potential Candidates for Vascularized Composite Allotransplants

    P. Duhamel, P. Grimbert, C. Suberbielle, C. Jacquelinet, B. Audry, L. Bargues, E. Bey, L. Lantieri, M. Hivelin

    Plastic and Reconstructive Surgery, Burn Intensive Care Unit, Hôpital d'Instruction des Armées Percy, Clamart, France; Nephrology and Transplantation, Hopital Henri Mondor-Assistance Publique Hôpitaux de Paris (APHP), Creteil, France; HLA and Histocompatibility Laboratory, Hopital Saint Louis-Assistance Publique Hôpitaux de Paris (APHP), Paris, France; Agence de la Biomédecine, Paris, France; Plastic and Reconstructive Surgery, Hopital Européen Georges Pompidou-Assistance Publiques Hôpitaux de Paris (APHP), Paris, France

    IntroductionVascularized composite allotransplants (VCA) allow reconstructions of extensive burns sequelae. Initial care requires blood transfusions and skin allografts that can all lead to HLA sensitization.…
  • 2013 American Transplant Congress

    Short Oxygenated Warm Perfusion Prior to Cold Preservation Improves Graft Survival in Rat Liver Transplantation from Non-Heart-Beating Donors

    K. Maida, Y. Akamatsu, Y. Hara, T. Kashiwadate, S. Miyagi, K. Miyazawa, N. Ohuchi

    Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan

    PURPOSE: We have previously reported that short oxygenated warm perfusion prior to cold preservation (SOWP) prevents warm ischemia-reperfusion injury in ex-vivo perfusion experiments using rat…
  • 2013 American Transplant Congress

    Once-Daily Extended-Release Formulation of Tacrolimus Does Not Require Double Dose of Twice-Daily Formulation of Tacrolimus in Kidney Transplantation

    H. Harada, N. Fukuzawa, K. Hotta, T. Seki, M. Togashi

    Kidney Transplant and Urologic Surgery, Sapporo City General Hospital, Sapporo, Hokkaido, Japan

    INTRODUCTION: Once-daily extended-release formulation of tacrolimus (QD-TAC) is expected to provide equal effects to the twice-daily formulation of tacrolimus (BID-TAC) with better drug adherence. According…
  • 2013 American Transplant Congress

    What Is the Implication of Pre-Donation Weight Loss to the Post-Donation Weight and Outcome of Living Donors

    A. Marsden, N. Waldron, R. Cooke, R. Chavez, A. Asderakis

    Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom

    Background: Living donors represent a third of kidney transplants performed in UK. A large proportion of potential donors are overweight but a number of those…
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