ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Anti-IL-6 Receptor (Anti-IL6R) Treatment Is Effective in Reducing Recall Antibody Responses in Sensitized HLA-A2 Skin Graft Recipients

    S. Jordan, G. Wu, N. Chai, I. Kim, A. Klein

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Background Sensitization to HLA antigens poses significant obstacles for successful transplantation and increase risk for antibody-mediated rejection (ABMR). IL-6/IL-6R interactions are known to have a…
  • 2013 American Transplant Congress

    Expedited Liver Allocation in the U.S.: A Critical Analysis

    P. Gaglio, J. Lindower, A. Principe, R. John, M. Kinkhabwala

    Montefiore Einstein Center for Transplantation, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY

    The purpose of this study is to critically analyze the distribution patterns and fate of donor livers that were allocated using an expedited placement (EP)…
  • 2013 American Transplant Congress

    Foetal Outcomes for Kidney Transplant Recipients

    M. Wyld, P. Clayton, S. Chadban, S. Alexander

    Sydney Medical School, University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; Australia and New Zealand Dialysis and Transplant Registry, Royal Adelaide Hospital, Adelaide, Australia; Centre for Kidney Research, The Children's Hospital Westmead, Sydney, Australia

    Purpose: Kidney transplantation greatly increases the chance of pregnancy and live birth in women with end stage kidney disease of reproductive age. While maternal outcomes…
  • 2013 American Transplant Congress

    ABO Antibody Removal of Plasmapheresis (PP) with Intravenous Immunoglobulin (IVIG) before ABO-Incompatible (ABOI) Kidney Transplantation

    D. Lee, B. Kim, J. Kim

    Medicine, Maryknoll General Hospital, Busan, Republic of Korea; Laboratory Medicine, Maryknoll General Hospital, Busan, Republic of Korea; Surgeon, Maryknoll General Hospital, Busan, Republic of Korea

    Background: ABOI kidney transplantation is an inevitable option to overcome organ shortage. Outcome of ABOI grafts improved and became equivalent to compatible grafts. There were…
  • 2013 American Transplant Congress

    Alpha 1-Antitrypsin (A1AT) Prevents Pulmonary Ischemia Reperfusion Injury in Rats

    J. Zhao, W. Gao, M. Cypel, S. Keshavjee, M. Liu

    Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, ON, Canada; Department of Thoracic Surgery, Tangdu Hospital, Forth Military Medical University, Xi'an, Shaanxi, China; Department of Surgery, University of Toronto, Toronto, ON, Canada

    Purpose: Even though lung transplantation has been the effective treatment for patients with end-stage lung diseases, pulmonary ischemia reperfusion (IR) injury continues to be the…
  • 2013 American Transplant Congress

    Conversion from Calcineurin Inhibitors to Everolimus Resulted in Decrease of Serum TGF-beta and Urinary NGAL in Renal Transplant Recipients

    N. Alpay, A. Ozkok, Y. Caliskan, T. Akagun, S. Cinar, G. Deniz, M. Sariyar, A. Yildiz

    Internal Medicine Nephrology Department, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey; Internal Medicine Nephrology Department, Medeniyet University, Istanbul, Turkey; Internal Medicine Nephrology Department, Giresun University, Giresun, Turkey; Institute of Experimental Medical Research, Istanbul University, Istanbul, Turkey; General Surgery Renal Transplantation, Medicana International Hospital, Istanbul, Turkey

    Background and Aim: Calcineurin inhibitor (CNI) treatment has been implicated for chronic allograft dysfunction in renal transplant recipients. We aimed to investigate the effects of…
  • 2013 American Transplant Congress

    Comparison of Pharmacokinetics of Once- and Twice-Daily Tacrolimus in Pediatric Kidney Transplant Recipients

    S. Shishido, Y. Hyoudo, H. Nihei, Y. Hamasaki, M. Muramatsu, Y. Niitsu, T. Kawamura, K. Sakai, A. Aikawa

    Pediatric Nephrology, Toho University, Faculty of Medicine, Tokyo, Japan; Nephrology, Toho University, Faculty of Medicine, Tokyo, Japan

    Aims: Few data is available regarding the pharmacokinetic (Pk) profile of newly developed modified-release once-daily formulation of tacrolimus (MR-Tac) in children. This study investigated Pk…
  • 2013 American Transplant Congress

    Somah – A Novel Modality for Subnormothermic Preservation of Donor Hearts

    S. Lowalekar, H. Cao, X. Lu, P. Treanor, H. Thatte

    Cardiac Surgery Division, VA Boston Healthcare System, Boston, MA; Surgery, Brigham and Women's Hospital, Boston, MA; Surgery, Harvard Medical School, Boston, MA

    Background- Donor hearts for transplant are stored in extreme hypothermic conditions to reduce ischemic damage. However, hypothermia-dependent cellular, biochemical, structural injuries are of concern. We…
  • 2013 American Transplant Congress

    Clinical Impact and Evolution of Humoral Immunity in a Randomized Multicenter Trial of Steroid Avoidance in Pediatric Renal Transplantation, The

    M. Sarwal, A. Chadhuri, M. Ozawa, M. Everly, R. Ettenger, V. Dharnidharka, M. Benfield, R. Mathias, A. Portale, R. McDonald, W. Harmon, D. Kershaw, V. Vehaskari, E. Kamil, H. Baluarte, B. Warady, T. Sigdel, H. Szu-chuan, H. Dai, M. Naesens, J. Waskerwitz, O. Salvatierra, P. Terasaki

    California Pacific Medical Center, San Francisco, CA; One Lambda, LA; For the Multicenter SNSO1 study, , CA

    PURPOSE: The development of anti-donor humoral responses after transplantation associates with higher risks for acute rejection and 1-year graft survival in adults, but the influence…
  • 2013 American Transplant Congress

    Strain Specific Induction of Regulatory T Cells by Plasmacytoid Dendritic Cells

    D. Ndishabandi, K. Shinoda, R. Colvin, A. Alessandrini

    Surgery, Massachusetts General Hospital, Boston; Pathology, Massachusetts General Hospital, Boston, MA

    Life sustaining, full MHC-mismatched mouse kidney transplants are spontaneously accepted in certain strain combinations (e.g., DBA/2 to B6), while some full MHC-mismatched mouse kidneys are…
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