2013 American Transplant Congress
Alpha 1-Antitrypsin (A1AT) Prevents Pulmonary Ischemia Reperfusion Injury in Rats
Purpose: Even though lung transplantation has been the effective treatment for patients with end-stage lung diseases, pulmonary ischemia reperfusion (IR) injury continues to be the…2013 American Transplant Congress
Conversion from Calcineurin Inhibitors to Everolimus Resulted in Decrease of Serum TGF-beta and Urinary NGAL in Renal Transplant Recipients
Background and Aim: Calcineurin inhibitor (CNI) treatment has been implicated for chronic allograft dysfunction in renal transplant recipients. We aimed to investigate the effects of…2013 American Transplant Congress
Comparison of Pharmacokinetics of Once- and Twice-Daily Tacrolimus in Pediatric Kidney Transplant Recipients
Aims: Few data is available regarding the pharmacokinetic (Pk) profile of newly developed modified-release once-daily formulation of tacrolimus (MR-Tac) in children. This study investigated Pk…2013 American Transplant Congress
TIMP-1 Deficiency Promotes p53 Pathway and Impairs Hepatocyte Proliferation in Liver Ischemia Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles
Hepatic ischemia/reperfusion injury (IRI) remains a challenge in organ transplantation. Tissue inhibitor of metalloproteinases-1 (TIMP-1) is the major endogenous regulator of matrix metalloproteinase-9 (MMP-9). While…2013 American Transplant Congress
Role of Deletion of Donor-Reactive T Cells in Maintaining Human Allograft Tolerance Achieved via Combined Kidney and Bone Marrow Transplantation (CKBMT)
BACKGROUND: The need for tolerance protocols in organ transplantation is underscored by the morbidity associated with chronic immunosuppressant use and the inability to prevent chronic…2013 American Transplant Congress
Predictors of Fibrosing Cholestatic Hepatitis Development Following Liver Transplantation: Potential Impact on Donor Selection and CMV Prophylaxis
Center for Liver Diseases, Carolinas Medical Center, Charlotte, NC
Introduction: Fibrosing cholestatic hepatitis (FCH) is an aggressive form of hepatitis C which is seen following liver transplantation (OLT) and it carries high mortality rate.…2013 American Transplant Congress
Deficiencies in Patients' Transplant Knowledge and Learning Activities Predicts Longer Time To Complete Kidney Transplant Evaluation
African-American (AA) end-stage kidney disease (ESKD) patients experience several disparities in kidney transplantation (KT), including an increased time to complete transplant evaluation, as compared to…2013 American Transplant Congress
Normative Values for Transplant Health-Related Quality of Life
Background. Health-related quality of life (HRQoL) evaluates health from the view point of the individual and preferences the quality of live versus the quantity of…2013 American Transplant Congress
False Hepatitis C Antibody Development in Left Ventricular Assist Device Recipients Who Proceed to Heart Transplantation
Purpose: Ventricular assist devices (VAD) have been shown to lead to immune activation and higher frequencies of autoantibodies. Previous research reports a rate of 30%…2013 American Transplant Congress
Altered Serum miR-326 and miR-142-3p Profiles during Acute Rejection after Heart Transplantation
IntroductionCirculating miRNAs may serve the purpose as practicable non-invasive biological marker of allograft status in heart transplanted patients, as they can be detected in serum…