2013 American Transplant Congress
Maintaining a Calcineurin-Inhibitor after the Diagnosis of PTLD Is Safe and Improves Renal Graft Survival
Post transplant lymphoproliferative disorder (PTLD) is the second most frequent neoplasia after renal transplantation. This life threatening disease corresponds to an uncontrolled proliferation of lymphocytes…2013 American Transplant Congress
ABO Antibody Removal of Plasmapheresis (PP) with Intravenous Immunoglobulin (IVIG) before ABO-Incompatible (ABOI) Kidney Transplantation
Background: ABOI kidney transplantation is an inevitable option to overcome organ shortage. Outcome of ABOI grafts improved and became equivalent to compatible grafts. There were…2013 American Transplant Congress
Alpha 1-Antitrypsin (A1AT) Prevents Pulmonary Ischemia Reperfusion Injury in Rats
Purpose: Even though lung transplantation has been the effective treatment for patients with end-stage lung diseases, pulmonary ischemia reperfusion (IR) injury continues to be the…2013 American Transplant Congress
Conversion from Calcineurin Inhibitors to Everolimus Resulted in Decrease of Serum TGF-beta and Urinary NGAL in Renal Transplant Recipients
Background and Aim: Calcineurin inhibitor (CNI) treatment has been implicated for chronic allograft dysfunction in renal transplant recipients. We aimed to investigate the effects of…2013 American Transplant Congress
Comparison of Pharmacokinetics of Once- and Twice-Daily Tacrolimus in Pediatric Kidney Transplant Recipients
Aims: Few data is available regarding the pharmacokinetic (Pk) profile of newly developed modified-release once-daily formulation of tacrolimus (MR-Tac) in children. This study investigated Pk…2013 American Transplant Congress
TIMP-1 Deficiency Promotes p53 Pathway and Impairs Hepatocyte Proliferation in Liver Ischemia Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles
Hepatic ischemia/reperfusion injury (IRI) remains a challenge in organ transplantation. Tissue inhibitor of metalloproteinases-1 (TIMP-1) is the major endogenous regulator of matrix metalloproteinase-9 (MMP-9). While…2013 American Transplant Congress
Role of Deletion of Donor-Reactive T Cells in Maintaining Human Allograft Tolerance Achieved via Combined Kidney and Bone Marrow Transplantation (CKBMT)
BACKGROUND: The need for tolerance protocols in organ transplantation is underscored by the morbidity associated with chronic immunosuppressant use and the inability to prevent chronic…2013 American Transplant Congress
Predictors of Fibrosing Cholestatic Hepatitis Development Following Liver Transplantation: Potential Impact on Donor Selection and CMV Prophylaxis
Center for Liver Diseases, Carolinas Medical Center, Charlotte, NC
Introduction: Fibrosing cholestatic hepatitis (FCH) is an aggressive form of hepatitis C which is seen following liver transplantation (OLT) and it carries high mortality rate.…2013 American Transplant Congress
Deficiencies in Patients' Transplant Knowledge and Learning Activities Predicts Longer Time To Complete Kidney Transplant Evaluation
African-American (AA) end-stage kidney disease (ESKD) patients experience several disparities in kidney transplantation (KT), including an increased time to complete transplant evaluation, as compared to…2013 American Transplant Congress
Increased Expression of CTLA-4 and PD-1 and Restricted Functionality as Typical Features of Varizella Zoster Specific T Cells in Patients with Acute Herpes Zoster
Varicella zoster virus (VZV) establishes lifelong persistence and immunocompromised patients such as hemodialysis and transplant recipients are at high risk for virus reactivation presenting as…