ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Impact of Matching Frequency in Kidney Paired Donation

    I. Ashlagi, R. Anderson, D. Gamarnik, G. Hil, M. Melcher, A. Roth

    Operations Management, Sloan School of Management, MIT, Cambridge, MA; Operations Research Center, MIT, Cambridge, MA; National Kidney Registry, NY; Surgery, Stanford, Palo Alto, CA; Economics, Stanford, Palo Alto, CA

    Introduction: Kidney Paired Donation (KPD) programs use algorithms to find cycles involving incompatible pairs, and chains, initiated with a non-directed donor. KPD programs generally match…
  • 2013 American Transplant Congress

    ABO-Incompatible Kidney Transplantation Protects the Graft from Natural Antibodies Induced Damage and Prevents Immune Responses to Donor HLA and Kidney Associated Self Antigens Leading to Long Term Rejection Free Survival

    V. Subramanian, C. Klein, D. Phelan, J. Wellen, W. Chapman, S. Shenoy, T. Mohanakumar

    Washington University, St. Louis, MO

    Background: There is increased interest in ABO-incompatible (ABOi) kidney transplantation (KTx) worldwide. With appropriate selection based on anti-ABO titer, reduction of natural antibodies (NAbs) by…
  • 2013 American Transplant Congress

    CD137 Signaling in Regulatory NK Cells Is Protective Against Liver Ischemia-Reperfusion Injury

    J. Lee, A. Kim, H. Kim, S. Park, S. Koo, H. Cho, B. Kwon

    Internal Medicine, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea; Surgery, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea; School of Biological Sciences, Ulsan University, Ulsan, Korea; Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea

    Liver ischemia-reperfusion injury (IRI) after liver transplantation is a major cause of delayed graft function. We previously demonstrated that the specific expressions of CD137 on…
  • 2013 American Transplant Congress

    Outcomes of Simultaneous Liver-Kidney Transplantation from DCD Organ Donors

    A. Barbas, W. Irish, A. Castleberry, K. Ravindra, B. Collins, D. Sudan, D. Vikraman

    Duke University Medical Center, Durham, NC; Clinical Trials and Consulting Services, Cincinnati, OH

    Simultaneous liver-kidney transplantation (SLKT) is being performed with greater frequency in the United States. Due to the shortage of available donors, organs obtained after cardiac…
  • 2013 American Transplant Congress

    Small Donor Size Adversely Impact Kidney Allograft Function Following Living Donor Kidney Transplant

    H. Khamash, R. Heilman, H. Chakkera, J. Huskey, N. Katariya, A. Moss, D. Mulligan, W. Hewitt, K. Reddy

    Mayo Clinic Arizona, Phoenix

    Background: We wanted to assess the impact of donor size and donor to recipient size mismatch on kidney allograft function following living donor kidney transplant.Methods:…
  • 2013 American Transplant Congress

    Determinants of Medication Misunderstanding and Non-Adherence among Kidney and Liver Transplant Recipients

    M. Serper, R. Patzer, K. Przytula, J. King, J. Levitsky, D. Ladner, R. Koval, M. Wolf

    Northwestern University Feinberg School of Medicine, Chicago, IL; Emory School of Medicine, Atlanta, GA

    OBJECTIVE: The study objective was to determine the prevalence and risk factors for medication non-nadherence and misunderstanding among solid organ transplant (SOT) recipients; and examine…
  • 2013 American Transplant Congress

    Pre-Transplant HLA Immunization in Kidney Transplant Recipients Is Characterized by an Activated Peripheral B Cell Phenotype and High Serum Levels of BAFF

    R. Snanoudj, S. Candon, D. Roelen, F. Claas, C. Legendre, L. Chatenoud

    INSERM U1013, Universite Paris Sorbonne Cite, Paris, France; Immunohematology, Leiden University Medical Center, Leiden, Netherlands; Transplantation, Necker Hospital, APHP, Paris, France

    Purpose. Our objective was to provide the first precise study of peripheral B cell phenotype and BAFF serum level in relation with pre-transplant HLA immunization.…
  • 2013 American Transplant Congress

    Fate of 535 Renal Allografts Retrieved from Donors after Cardiac Death and Risk Factors Affecting Long-Term Graft Survival (Single Center Experience during Three Decades), The

    M. Kusaka, Y. Kubota, M. Takenaka, N. Fukami, H. Sasaki, R. Shiroki, T. Kenmochi, K. Hoshinaga

    Department of Urology, Fujita-Health University, Toyoake, Aichi, Japan; Department of Organ Transplant Surgery, Fujita-Health University, Toyoake, Aichi, Japan

    Introduction: The kidneys procured from deceased donors in donation after cardiac death (DCD) hold great potential to expand the donor pool but have not yet…
  • 2013 American Transplant Congress

    Effect of EGF and FSP1 Targeting of Nanoparticle Delivery of IL-10 and GM-CSF Following Acute Kidney Injury, The

    M. Tobin, M. O'Connor, E. Szilagyi, N. Capezio, L. Nuñez, R. Spretz, S. Noriega, A. Bartholomew

    Surgery, University of Illinois at Chicago, Chicago, IL; LNK Chemsolutions, Lincoln, NE

    Study Purpose: Renal fibrosis is a failure of regenerative mechanisms; strategies aimed towards identifying suitable targets for fibrotic tissue may hold promise in mitigating or…
  • 2013 American Transplant Congress

    Phenotype and Functionality of BKV-Specific T Cells Are Differently Affected by Distinct Immunosuppressive Drugs

    B. Weist, M. Schmueck, N. Babel, P. Reinke

    Department of Nephrology, Charité Universitätsmedizin, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin, Berlin, Germany

    Background: Immunosuppression of kidney allograft recipients is currently the indispensable method to avoid graft rejection. Nevertheless, suppression of the cellular immunity is an important risk…
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