2013 American Transplant Congress
Overcoming Hyperacute Rejection of Monkey ABO-Incompatible Renal Transplantation Using a Complement Inhibition-Based Strategy
Background: It has been demonstrated that complement inhibition-based strategy enables renal allograft accommodation and long-term engraftment in donor skin-presensitized monkeys. The effect of the same…2013 American Transplant Congress
CD3 Antibody-Induced Transplant Tolerance Relies on In Situ TGF-Beta and PD-1 Signaling in T Cells
CD3 antibody therapy, successfully used to treat patients with recent onset type 1 diabetes, can restore self-tolerance to autoantigens. We extented these tolerogenic properties to…2013 American Transplant Congress
Pretransplant Donor-Specific HLA-Cw Antibodies and Risk of Antibody-Mediated Rejection
Donor-specific anti-HLA antibodies (DSA) cause acute and chronic antibody-mediated rejection (AMR) and significantly compromise allograft survival. Clinical relevance of antiHLA-Cw antibodies is still unclear with…2013 American Transplant Congress
Renal Graft Survival Post Thoracic and Abdominal Transplant: A Single Center Experience
University of Pittsburgh, Pittsburgh, PA
Introduction: ESRD is a common complication in patients with non-renal solid organ transplantation and such patients are living longer to receive kidney transplants. There is…2013 American Transplant Congress
Is Uric Acid an Independent Risk Factor for Graft Failure in Kidney Transplant Recipients?
Background: Hyperuricemia is frequently observed in kidney transplant recipients and it has been implicated in poor allograft function and survival. However, this association remains controversial…2013 American Transplant Congress
Differential Regulation of Regulatory T Cells and Th17 Cells by mTOR Inhibitor in Kidney Transplant Recipients
Background : Accumulating evidence suggests that Treg/Th17 axis have important role in long term allograft survival in kidney transplantation. The aim of this study is…2013 American Transplant Congress
Decreasing Incidence of New-Onset Diabetes after Kidney Transplantation
Directorate of Nephrology and Transplantation, University Hospital of Wales, Cardiff, United Kingdom
Aim: The incidence of new-onset diabetes after kidney transplantation (NODAT) is largely influenced by immunosuppressive drugs. There is some evidence that its incidence is lower…2013 American Transplant Congress
One Year Results of the Effects of Rituximab on Acute Humoral Rejection in Renal Transplantation: RITUX ERAH, a Multicenter Randomized Placebo Controlled Trial
Background: The treatment of acute humoral rejection (AHR) is currently based on the combination of plasmepheresis (PE), intravenous immune globulin (IVIg) and corticosteroids (CS). Patients…2013 American Transplant Congress
Risk Factors for Early Onset of Acute Kidney Injury and Subsequent Development of Chronic Renal Disease after Liver Transplantation
Background. Renal impairement is one of the most common complications following liver transplantation (LT) and it is associated with an increased length of stay in…2013 American Transplant Congress
mTOR, but Not Calcineurin, Inhibition Safeguards Anti-Tumoral CD8 Immunity in Transplant Recipients
The purpose of this study was to investigate the role of mTOR versus calcineurin inhibition in anti-tumoral CD8+ T cell responses in posttransplant malignancy. To…
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