ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Renal Graft Survival Post Thoracic and Abdominal Transplant: A Single Center Experience

    R. Nusrat, S. Hariharan, A. Tevar, R. Shapiro, A. Humar, P. Sood

    University of Pittsburgh, Pittsburgh, PA

    Introduction: ESRD is a common complication in patients with non-renal solid organ transplantation and such patients are living longer to receive kidney transplants. There is…
  • 2013 American Transplant Congress

    Is Uric Acid an Independent Risk Factor for Graft Failure in Kidney Transplant Recipients?

    E. Kim, O. Famure, Y. Li, J. Kim

    Multi-Organ Transplant Program, Toronto General Hospital, University of Toronto, Toronto, ON, Canada; Medicine (Nephrology), Toronto General Hospital, University of Toronto, Toronto, ON, Canada

    Background: Hyperuricemia is frequently observed in kidney transplant recipients and it has been implicated in poor allograft function and survival. However, this association remains controversial…
  • 2013 American Transplant Congress

    Differential Regulation of Regulatory T Cells and Th17 Cells by mTOR Inhibitor in Kidney Transplant Recipients

    K. Kim, B. Chung, B. Kim, M. Cho, C. Yang

    Convergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

    Background : Accumulating evidence suggests that Treg/Th17 axis have important role in long term allograft survival in kidney transplantation. The aim of this study is…
  • 2013 American Transplant Congress

    Decreasing Incidence of New-Onset Diabetes after Kidney Transplantation

    P. Nagaraja, V. Ravindran, K. Baboolal

    Directorate of Nephrology and Transplantation, University Hospital of Wales, Cardiff, United Kingdom

    Aim: The incidence of new-onset diabetes after kidney transplantation (NODAT) is largely influenced by immunosuppressive drugs. There is some evidence that its incidence is lower…
  • 2013 American Transplant Congress

    One Year Results of the Effects of Rituximab on Acute Humoral Rejection in Renal Transplantation: RITUX ERAH, a Multicenter Randomized Placebo Controlled Trial

    B. Sautenet, G. Blancho, M. Buchler, E. Morelon, O. Toupance, B. Barrou, D. Ducloux, B. Hurault de Ligny, B. Moulin, A. Le Gouge, Y. Lebranchu

    Nephrology, CHRU Bretonneau, Tours, France; CIC INSERM 202, CHRU Bretonneau, Tours, France; Nephrology, CHRU, Nantes, France; Nephrology, CHRU Edouard Herriot, Lyon, France; Nephrology, CHRU Maison Blanche, Reims, France; Urology, CHRU Pitie Salpetriere, Paris, France; Nephrology, CHRU Saint Jacques, Besançon, France; Nephrology, CHRU, Caen, France; Nephrology, CHRU Civil, Strasbourg, France

    Background: The treatment of acute humoral rejection (AHR) is currently based on the combination of plasmepheresis (PE), intravenous immune globulin (IVIg) and corticosteroids (CS). Patients…
  • 2013 American Transplant Congress

    Risk Factors for Early Onset of Acute Kidney Injury and Subsequent Development of Chronic Renal Disease after Liver Transplantation

    D. Tomescu, M. Popescu, G. Droc, S. Dima, I. Popescu

    Anesthesia and Intensive Care, Fundeni Clinical Institute, Bucharest, Romania; Center of General Surgery and Liver Transplantation, Fundeni Clinical Insitute, Bucharest, Romania

    Background. Renal impairement is one of the most common complications following liver transplantation (LT) and it is associated with an increased length of stay in…
  • 2013 American Transplant Congress

    mTOR, but Not Calcineurin, Inhibition Safeguards Anti-Tumoral CD8 Immunity in Transplant Recipients

    J. Rovira, M. Sabet-Baktach, M. Lantow, E. Eggenhofer, G. Koehl, H. Schlitt, J. Campistol, E. Geissler, A. Kroemer

    Department of Surgery, University Hospital Regensburg, Regensburg, Germany; Department of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain

    The purpose of this study was to investigate the role of mTOR versus calcineurin inhibition in anti-tumoral CD8+ T cell responses in posttransplant malignancy. To…
  • 2013 American Transplant Congress

    Microcirculation Inflammation Is Superior to Peritubular Capillary Basement Membrane Multilayering for Outcome Prediction in Renal Transplant Patients with De Novo Donor-Specific Antibodies

    H. de Kort, M. Willicombe, P. Brookes, L. Moran, E. Santos-Nunez, J. Galliford, D. Taube, A. McLean, J. Moss, H. Cook, C. Roufosse

    Imperial College NHS Trust, London, United Kingdom; , United Kingdom

    In renal transplant patients with de novo donor-specific antibodies (DSA) we compared peritubular capillary basement membrane multilayering (PTCBML) counts with microcirculation inflammation (MI) score to…
  • 2013 American Transplant Congress

    Acute Rejection on Surveillance Biopsies Is a Predictor of Functional Decline in Kidney Transplants over Long-Term Follow-Up

    A. Desai, N. Nader, J. Brar, S. Patel, M. Laftavi, R. Venuto, M. Zachariah

    Nephrology and Transplantation, SUNY at Buffalo, Buffalo, NY; Anesthesiology, VA Medical Center and SUNY at Buffalo, Buffalo, NY

    Background: Identifying specific factors that are predictive of renal allograft functional decline is important toward prolonging graft survival. Few studies have addressed specific histologic diagnoses…
  • 2013 American Transplant Congress

    Epigenetic Mechanisms Underlying Allograft Rejection: Role of the Histone Acetyltransferase, GCN-5 in T Cell Activation, Proliferation and Cytokine Production

    C. Bao, Y. Liu, L. Wang, R. Han, S. Dent, W. Hancock

    Cardiothoracic Surgery, Shanghai Jiaotong University School of Medicine, Shanghai, China; Path & Lab Med, CHOP/UPenn, Philadelphia; Carcinogenesis, MD Anderson Cancer Center, Houston

    There is currently no literature on the roles of histone acetyltransferases (HATs) in allograft biology, despite the central roles that these enzymes are thought to…
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