ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    High Cost of High MELD Waitlisted Patients, The

    D. Axelrod, N. Dzebisashvili, K. Lentine, J. Tuttle-Newhall, R. Freeman, M. Schnitzler

    Surgery, DHMC, Lebanon, NH; Transplant, SLU, St. Louis, MO

    Introduction: Economic analysis of liver transplant (LT) practice has generally focused on the LT episode and post-LT care. Consequently, the economic impact of the geographic…
  • 2013 American Transplant Congress

    Cardiovascular Disease Markers in Kidney Transplant Recipients Converted from Calcineurin Inhibitors to Everolimus

    R. Schiavelli, C. Cuevas, E. Alvarenga, M. Ponte, A. Otero, F. Margulis

    Unidad de Nefrologia y Trasplante Renal, Hospital Argerich, Buenos Aires, Argentina; Medicina, Novartis Argentina SA, Caba, Argentina

    Introduction: The prevalence of cardiovascular disease in kidney transplant recipients (KTR) is four times higher than in general population. Pulse wave velocity is considered an…
  • 2013 American Transplant Congress

    Liver Preservation with Machine Perfusion under Full Oxygenation Using a New Cell-Free Oxygen-Carrier Solution

    P. Fontes, W. Marsh, R. Lopez, K. Soltys, V. Scott, A. van der Plaats, W. Light, S. Shiva, M. Minnervinni, A. Demetris

    Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; Anesthesia, University of Pittsburgh Medical Center, Pittsburgh, PA; Organ Assist, Groningen, Netherlands; OPK Biotech, Cambridge, MA; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA; McGowan Institue of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA

    Background: Machine perfusion (MP) has been implemented either under hypothermic and anoxic conditions or under normothermia with full oxygenation using blood as perfusate. This is…
  • 2013 American Transplant Congress

    Long Term Clinical Outcome of Liver Transplant Recipients Who Successfully Withdrawn Immunosuppression, The

    T. Manzia, R. Angelico, L. Toti, L. Fazzolari, L. Tariciotti, D. Sforza, M. Manuelli, V. Tognoni, A. Di Giorgio, G. Tisone

    UOC Chirurgia dei Trapianti, Tor Vergata University, Rome, Italy

    Background. Clinical operational tolerance was defined as stable normal graft function in the total absence immunosuppression (IS). It may be achieved in up to 20%…
  • 2013 American Transplant Congress

    Leflunomide Confers Protection to the Post-Ischemic Kidney Via Inhibition of GADD153 Expression and Inflammation

    A. Ghaffari, M. Masoumy, J. Liu, B. Babak

    Department of Surgery, Georgia Health Sciences University, Augusta, GA; Department of Oral Biology, Georgia Health Sciences University, Augusta, GA

    Background: Ischemia reperfusion injury is associated with a number of clinical conditions including renal transplantation. We recently showed that pretreatment of mice with leflunomide significantly…
  • 2013 American Transplant Congress

    High MFI Preformed Class II HLA Donor Specific Alloantibodies Increase the Risk of Early Rejection and Death after Liver-Transplantation

    J. O'Leary, H. Kaneku, L. Jennings, B. Susskind, P. Terasaki, G. Klintmalm

    Annette C & Harold C Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX; Terasaki Foundation Laboratory, Los Angeles, CA

    Aim: To evaluate the impact of preformed donor specific alloantibodies (DSA) on the risk of rejection and patient survival after isolated liver transplantation (LT). Methods:…
  • 2013 American Transplant Congress

    Early Elevated Everolimus Levels Are Associated with More Toxicities without Improved Efficacy

    D. Taber, L. Belk, J. McGillicuddy, C. Bratton, N. Pilch, P. Baliga, K. Chavin

    Transplant, MUSC, Charleston, SC

    Background: Everolimus (ERL) is an mTOR generally utilized in CNI minimization or withdrawal regimens for kidney transplantation (KTX). The aim of this study was to…
  • 2013 American Transplant Congress

    Comparison of Everolimus Pharmacokinetics and Pharmacodynamics between Ethnicities

    D. Taber, L. Belk, N. Pilch, J. McGillicuddy, C. Bratton, K. Chavin, P. Baliga

    Transplant, MUSC, Charleston, SC

    Background: Everolimus is an mTOR generally utilized in CNI minimization or withdrawal regimens for kidney transplantation. The aim of this study was to compare pharmacokinetic…
  • 2013 American Transplant Congress

    Lack of Association between Infection and Increased Sensitization in Kidney Transplant Recipients

    A. Aljanabi, L. Kayler, A. Colovai, P. Masiakos, M. Ajaimy, E. Akalin

    Montefiore-Einstein Transplant Center, Bronx, NY

    Background: We investigated the association between bacterial/fungal infection and increased sensitization in post-transplant kidney transplant recipients due to interaction between innate and adaptive immunity and/or…
  • 2013 American Transplant Congress

    Ileal FGF15/19 to Hepatocyte FGFR4 Axis Is a Novel Positive Regulator of Liver Regeneration after Partial Hepatectomy in Mice

    Z. Guo, Q. Li, X. Zhu, X. He

    Organ Transplant Center, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Liver regeneration after partial hepatectomy (PH) or living donor liver transplantation (LDLT) is a complicated biological process, which is not only regulated by liver itself…
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