2013 American Transplant Congress
Deceased Kidney Donor Acute Tubular Necrosis and the Development of Delayed Graft Function
Background: Acute kidney injury (AKI) in the donor kidney may contribute to delayed graft function (DGF), heightened immunologic risk, and progressive graft fibrosis, thereby affecting…2013 American Transplant Congress
Outcomes Following Positive Crossmatch Renal Transplantation Despite Failure To Convert to Negative Flow Crossmatch after Desensitization
Purpose: Determine outcomes of positive crossmatch (PXM) renal transplant recipients that failed to convert to negative flow cytometry crossmatch (FCXM) despite desensitization.Methods: All patients that…2013 American Transplant Congress
Diabetes Significantly Impacts Quality of Life Following Kidney Transplant
Dept of Pharmacy Services, MUSC, Charleston, SC; Dept of Transplant Surgery, MUSC, Charleston, SC
Purpose: Kidney transplant (KTx) has the potential to substantially improve quality of life (QOL) through improvements in performance status and life expectancy. Few studies have…2013 American Transplant Congress
North American Results from the Multicenter Randomized Trial of Everolimus vs Mycophenolate Mofetil in Heart Transplantation
Purpose: 24-month (M) results of a randomized, open-label, multinational study (A2310) comparing efficacy and safety of everolimus (EVR) and mycophenolate mofetil (MMF) in de novo…2013 American Transplant Congress
Most Late Kidney Graft Failures after Simultaneous Kidney-Pancreas Transplant (SPK) Are Due to Non-Immunological Graft Injury
Background: Late allograft failure is one of the critical issues in renal transplantation today. The relative importance of immunological versus non-immunological causes of chronic kidney…2013 American Transplant Congress
Comparison of Hepatitis C Recurrence in Orthotopic Liver Transplant Recipients Receiving Antibody Induction Versus No Antibody Induction
Purpose: Compare the incidence of hepatitis C virus (HCV) recurrence in orthotopic liver transplant (OLT) recipients receiving induction to subjects that were transplanted without induction…2013 American Transplant Congress
Endodermal Precursor Cells Derived from Embryonic Stem Cells Can Engraft in Mouse Liver
Surgery, University of Florida, Gainesville, FL
Purpose: Embryonic stem (ES) cells have been shown to have great value therapeutically due to their limitless capacity for self-renewal and proliferation, and their ability…2013 American Transplant Congress
Determinants of Late Acute Rejection in Pediatric & Adolescent Kidney Transplant Recipients
Pediatric Nephrology, Children's National Medical Center, Washington, DC
Background: Long-term graft function has not kept pace with short-term graft survival in children. Late Acute Rejection (LAR) episodes are in part responsible for the…2013 American Transplant Congress
Immune Cell Derived C3a and C5a Mediate Human Alloreactive T Cell Immunity
Renal Division, Department of Medicine, Mount Sinai School of Medicine, New York, NY
Background: Murine studies showed immune cell derived C3a/C5a are costimulatory intermediaries required for T cell activation. We investigated how these concepts apply to human alloreactive…2013 American Transplant Congress
Nonmyeloablative Conditioning Regimen with B Cell Depletion and Long-Term Outcome of HLA Mismatched Combined Kidney and Bone Marrow Transplantation without Maintenance Immunosuppression
Background: We report the long-term results (up to 10 years) of one-haplotype HLA mismatched kidney transplantation without maintenance immunosuppression (IS) following combined kidney and bone…
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