ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Unique Role of Antibodies to MHC Class I in the Induction of Inflammatory Cellular Infiltration: Selective Role for CD4 and CD8 Cells in Development of Autoimmunity and Obliterative Airway Disease

    V. Tiriveedhi, M. Takenaka, N. Sarma, A. Gelman, T. Mohanakumar

    Surgery, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO

    Background: Anti-MHC class I administration into lungs results in cellular infiltration, epithelial damage, immune responses to lung associated self-antigens(SAgs), KΑ1 tubulin (KΑ1T) and Collagen V…
  • 2013 American Transplant Congress

    IL-2 Antagonist Induction Therapy Preserves Renal Function in Liver Transplant Recipients

    A. Mardis, H. Meadows, D. Taber, N. Pilch, J. Fleming, C. Jordan, K. Morbitzer, C. Makowski, J. McGillicuddy, C. Bratton, K. Chavin, P. Baliga

    Pharmacy, MUSC, Charleston, SC; Transplant, MUSC, Charleston, SC

    Background: Studies have produced varying results regarding whether IL-2 antagonist induction improves outcomes, including renal function and patient and graft survival in liver transplantation. This…
  • 2013 American Transplant Congress

    NASH Recurrence: Focus on Preventing New Onset Diabetes?

    C. Jordan, N. Pilch, D. Taber, H. Meadows, J. Fleming, A. Mardis, K. Morbitzer, C. Makowski, J. McGillicuddy, C. Bratton, A. Lin, P. Baliga, K. Chavin

    Pharmacy, MUSC, Charleston, SC; Transplant, MUSC, Charleston, SC

    Background: The aim of this study was to evaluate the risk factors and associated outcomes with NASH recurrence following liver transplant.Methods: Single center retrospective longitudinal…
  • 2013 American Transplant Congress

    Metabolomic Distinctions between Renal Allograft Recipients on Monotherapy Sirolimus or Tacrolimus Maintenance Therapy

    S. Kim, Y. Park, J. Cheeseman, A. Mehta, D. Jones, A. Kirk

    Emory Transplant Center, Emory University, Atlanta, GA; Clinical Biomarkers Laboratory, Emory University, Atlanta, GA

    Background. Sirolimus and Tacrolimus have distinct mechanisms of action with distinct side effect profiles. In order to gain mechanistic insights into the differing effects of…
  • 2013 American Transplant Congress

    Ciprofloxacin Combined with SMZ/TMP Prophylaxis Reduces the Incidence of UTIs Following Kidney Transplantation

    D. Wojciechowski, S. Chandran

    UCSF, San Francisco; UCSF, San Francisco

    Introduction:Urinary tract infections (UTIs) are major causes of morbidity and recurrent hospitalizations following kidney transplantation. To date there are no guidelines on antibiotic prophylaxis for…
  • 2013 American Transplant Congress

    Delayed Kidney Graft Function in SPK Recipients Is Associated with Poor Long-Term Outcomes

    B. Muth, B. Astor, D. Kaufman, H. Sollinger, R. Hofmann, M. Mohamed, V. Vidyasagar, J. Pirsch, J. Bellingham, J. Odorico, A. Djamali

    Department of Medicine, University of Wisconsin, Madison, WI; Department of Surgery, University of Wisconsin, Madison, WI

    The association of delayed kidney graft function (DGF) with long-term clinical outcomes in simultaneous pancreas kidney (SPK) transplant recipients is largely unknown. To address this…
  • 2013 American Transplant Congress

    Antiviral Prophylaxis for HBsAg-Positive Renal Transplant Recipients Treated with Rituximab®

    Y. Kim, Y. Han, J. Jung, H. Cho, Y. Lim, S. Park, D. Han

    Surgery, Asan Medical Center, Seoul, Republic of Korea; Gastroenterology, Asan Medical Center, Seoul, Republic of Korea; Nephrology, Asan Medical Center, Seoul, Republic of Korea

    The risk of Hepatitis B virus (HBV) reactivation under immunosuppressant has been well known. Especially, rituximab® is identified as strong risk factors of HBV reactivation…
  • 2013 American Transplant Congress

    Disease Severity Index Based on Dual Cholate Clearances and Shunt Identifies Primary Sclerosing Cholangitis Waiting List Patients at Risk for Clinical Complications, A

    S. Helmke, A. Wallack, A. Herman, H. Isberg, S. Lauriski, G. Everson

    Gastroenterology and Hepatology, University of Colorado, Aurora, CO

    A. Purpose: MELD may not adequately assess the risks for clinical complications in listed Primary Sclerosing Cholangitis (PSC) patients compared to a disease severity index…
  • 2013 American Transplant Congress

    Treatment Option in Diabetic End Stage Renal Disease Patients with Potential Living Kidney Donor: PAK vs. SPLK

    J. Jung, Y. Kim, Y. Han, Y. Chung, H. Cho, J. Park, D. Han

    Department of Surgery, Asan Medical Center, Seoul, Republic of Korea; Department of Endocrinology, Asan Medical Center, Seoul, Republic of Korea

    In diabetic patients with end stage renal disease who has a potential living kidney donor, pancreas after living kidney transplantation (PAK) or simultaneous cadaveric pancreas…
  • 2013 American Transplant Congress

    Prolonged Cold Ischemia Increases the Early Infiltration and Effector Functions of Memory CD8 T Lymphocytes in Cardiac Allografts

    C. Su, S. Iida, T. Abe, R. Fairchild

    Immunology, Cleveland Clinic, Cleveland, OH

    Introduction: During organ transplantation, ischemia-reperfusion injury (IRI) is an inescapable challenge that detrimentally impacts graft outcome. While I/R induced molecular mechanisms mediating injury of ischemic…
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