2013 American Transplant Congress
Effects of Locoregional Treatment and “Downstaging” on Long-Term Post-Liver Transplant Outcomes for Patients with Hepatocellular Carcinoma
Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH; Research, UNOS, Richmond, VA
IntroductionLocoregional therapy (LRT) has been used to stabilize tumor growth for patients with hepatocellular carcinoma (HCC) waiting for liver transplantation (LT). However, the long-term effects…2013 American Transplant Congress
Improved Renal Function of an Everolimus/Enteric-Coated Mycophenolate Sodium Regimen after Calcineurin Inhibitor Withdrawal in De Novo Renal Transplant Patients: 5 Years Follow-Up of the ZEUS Trial
ZEUS Study Group, Germany; Novartis Pharma, Nuremberg, Germany
Aim: To follow-up (FU) on renal function (RF), efficacy and safety after conversion to an Everolimus (EVE)/Enteric-Coated Mycophenolate Sodium (EC-MPS) regimen after cyclosporine A (CsA)…2013 American Transplant Congress
Tauroursodeoxycholic Acid Alleviate Ischemia-Reperfusion Injury in Donation after Cardiac Death Liver Transplantation
Background Donation after Cardiac Death (DCD) liver graft can provide possible and practical solutions to the organ shortage crisis, but extended warm ischemia time aggravates…2013 American Transplant Congress
Determinants of Late Acute Rejection in Pediatric & Adolescent Kidney Transplant Recipients
Pediatric Nephrology, Children's National Medical Center, Washington, DC
Background: Long-term graft function has not kept pace with short-term graft survival in children. Late Acute Rejection (LAR) episodes are in part responsible for the…2013 American Transplant Congress
Immune Cell Derived C3a and C5a Mediate Human Alloreactive T Cell Immunity
Renal Division, Department of Medicine, Mount Sinai School of Medicine, New York, NY
Background: Murine studies showed immune cell derived C3a/C5a are costimulatory intermediaries required for T cell activation. We investigated how these concepts apply to human alloreactive…2013 American Transplant Congress
Nonmyeloablative Conditioning Regimen with B Cell Depletion and Long-Term Outcome of HLA Mismatched Combined Kidney and Bone Marrow Transplantation without Maintenance Immunosuppression
Background: We report the long-term results (up to 10 years) of one-haplotype HLA mismatched kidney transplantation without maintenance immunosuppression (IS) following combined kidney and bone…2013 American Transplant Congress
Role of Eosinophils in the Induction and Maintenance of the Alloantibody Response, The
Department of Medicine, Mount Sinai School of Medicine, New York
Background: Delineating mechanisms of alloantibody formation and maintenance could guide development of novel therapies aimed at treating antibody mediated transplant rejection. Published work from 2011…2013 American Transplant Congress
Factors Implicated in the Expression of Selenium Binding Protein 1 in Chronic Allograft Vasculopathy
Background: Selenium binding protein-1 (SBP-1) has been implicated in intracellular protein trafficking and secretion. In a rhesus monkey kidney transplant model we previously demonstrated that…2013 American Transplant Congress
Spectrum of Renal Pathology and Gene Expression Profiles of Kidney Biopsies in Patients with Cirrhosis Listed for Liver Transplantation
Transplantation, Montefiore Medical Center, Bronx, NY
Introduction: We previously demonstrated universal glomerular abnormalities in kidney biopsies after orthotopic liver transplantation (OLT). We hypothesize that these changes exist prior to OLT and…2013 American Transplant Congress
Where Are the Real Barriers in Post Mortem Organ Donation?
Low organ donation rate from deceased donors (DD) is believed to result from the societal misperception and non-acceptance of brain death.However, it has been shown…
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