ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 24

    K. Budde, W. Arns, C. Sommerer, F. Lehner, M. Zeier, H. Neumayer, M. Guba, J. Jacobi, P. Weithofer, C. May, D. Baeumer, E. Paulus, O. Witzke

    HERAKLES Study Group, Germany; Novartis Pharma, Nuremberg, Germany

    Aim: To follow up (FU) on the evolution of renal function (RF) of immunosuppressive regimens with different calcineurin inhibitor (CNI) exposure at month (Mo)24 post…
  • 2013 American Transplant Congress

    Kidney Discard Reasons by Kidney Donor Profile Index (KDPI)

    L. Malinzak, A. Patel, M. Goggins, J. Denny, D. Kim, L. Yessayan, M. Weitzer

    Transplant Institute, Henry Ford Health System, Detroit, MI; School of Medicine, Wayne State University, Detroit, MI

    KDPI summarizes the risk of donor kidney graft failure based on clinical and demographic parameters. We hypothesize that discard of a kidney with low KDPI…
  • 2013 American Transplant Congress

    Single Donor-Derived Strongyloides in Solid Organ Transplants

    M. Le, H. Clauss, J. Pasko, K. Ravin, D. Muchant, A. Hasan, A. Kotru, C. Varma, G. Cipollina

    Geisinger Medical Center, Danville; Temple University Hospital, Philadelphia

    CDC was notified of Strongyloides infection in transplant recipients of kidneys, pancreas and heart from same deceased donor. Concern for donor-derived strongyloidiasis prompted an investigation…
  • 2013 American Transplant Congress

    First Year Mild Renal Insufficiency Associated with Increased Mortality after Heart Transplant

    J. Patel, M. Kittleson, M. Rafiei, A. Osborne, D. Chang, L. Czer, J. Kobashigawa

    Cedars-Sinai Heart Institute, Los Angeles, CA

    BACKGROUND: Renal failure has been a consistent risk factor for mortality after heart transplantation. From the ISHLT Registry approximately one third of patients have an…
  • 2013 American Transplant Congress

    Deceased Kidney Donor Acute Tubular Necrosis and the Development of Delayed Graft Function

    I. Hall, P. Reese, F. Weng, B. Schroppel, M. Doshi, R. Hasz, W. Reitsma, M. Goldstein, K. Hong, C. Parikh

    Yale University, New Haven, CT; University of Pennsylvania, Philadelphia, PA; Barnabas Health, Livingston, NJ; Mount Sinai School of Medicine, New York, NY; Wayne State University, Detroit, MI; Gift of Life Institute, Philadelphia, PA; New Jersey Sharing Network, New Providence, NJ

    Background: Acute kidney injury (AKI) in the donor kidney may contribute to delayed graft function (DGF), heightened immunologic risk, and progressive graft fibrosis, thereby affecting…
  • 2013 American Transplant Congress

    Outcomes Following Positive Crossmatch Renal Transplantation Despite Failure To Convert to Negative Flow Crossmatch after Desensitization

    S. Patel, J. Joseph, S. Akkina, P. West-Thielke, J. Thielke, J. Oberholzer, E. Benedetti

    Pharmacy Practice, University of Illinois Hospital and Health Sciences System, Chicago, IL; Medicine, University of Illinois Hospital and Health Sciences System, Chicago, IL; Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL

    Purpose: Determine outcomes of positive crossmatch (PXM) renal transplant recipients that failed to convert to negative flow cytometry crossmatch (FCXM) despite desensitization.Methods: All patients that…
  • 2013 American Transplant Congress

    Diabetes Significantly Impacts Quality of Life Following Kidney Transplant

    C. Musgrave, N. Pilch, H. Meadows, J. McGillicuddy, C. Bratton, K. Chavin, P. Baliga, D. Taber

    Dept of Pharmacy Services, MUSC, Charleston, SC; Dept of Transplant Surgery, MUSC, Charleston, SC

    Purpose: Kidney transplant (KTx) has the potential to substantially improve quality of life (QOL) through improvements in performance status and life expectancy. Few studies have…
  • 2013 American Transplant Congress

    North American Results from the Multicenter Randomized Trial of Everolimus vs Mycophenolate Mofetil in Heart Transplantation

    J. Kobashigawa, D. Pauly, H. Ross, A. Kfoury, A. Van Bakel, D. Patel, A. Wiland, P. Lopez, A. Balfour, R. Starling, H. Eisen

    Cedars-Sinai Heart Institute, CA; University of Florida College of Medicine, FL; Toronto General Hospital, Toronto, Canada; Intermountain Medical Center, UT; Medical University of South Carolina, SC; Novartis Pharmaceuticals Corp, NJ; Novartis Pharma AG, Basel, Switzerland; Cleveland Clinic, OH; Drexel University College of Medicine, PA

    Purpose: 24-month (M) results of a randomized, open-label, multinational study (A2310) comparing efficacy and safety of everolimus (EVR) and mycophenolate mofetil (MMF) in de novo…
  • 2013 American Transplant Congress

    Most Late Kidney Graft Failures after Simultaneous Kidney-Pancreas Transplant (SPK) Are Due to Non-Immunological Graft Injury

    Z. Stewart, L. Hunsicker

    Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA; Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA

    Background: Late allograft failure is one of the critical issues in renal transplantation today. The relative importance of immunological versus non-immunological causes of chronic kidney…
  • 2013 American Transplant Congress

    Comparison of Hepatitis C Recurrence in Orthotopic Liver Transplant Recipients Receiving Antibody Induction Versus No Antibody Induction

    S. Patel, P. West-Thielke, H. Jeon, E. Benedetti, J. Thielke

    Pharmacy Practice, University of Illinois Hospital and Health Sciences System, Chicago, IL; Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL

    Purpose: Compare the incidence of hepatitis C virus (HCV) recurrence in orthotopic liver transplant (OLT) recipients receiving induction to subjects that were transplanted without induction…
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