2013 American Transplant Congress
Irradiation and T Cell Depletion Augment Bone Marrow-Derived Chimerism at the Cost of Morbidity and Mortality in a Non-Human Primate Model of Vascularized Composite Allotransplantation
PurposeWe have shown that vascularized bone marrow (VBM) prolongs vascularized composite allograft survival in nonhuman primates (NHP). To explore the potential for chimerism and tolerance,…2013 American Transplant Congress
Iothalamate Urinary Clearance May Be Unreliable: A Comparison to Modification of Diet in Renal Disease in Renal Transplant Patients
Purpose: The gold standard of measuring glomerular filtration rate (mGFR) is to calculate the urinary clearance of exogenous markers, such as iothalamate (CLIO), yet such…2013 American Transplant Congress
Impact of Pre-Existing and New Onset Diabetes on Hepatitis C Recurrence Following Liver Transplant, The
Pharmacy, MUSC, Charleston, SC; Surgery, MUSC, Charleston, SC
Background: Hepatitis C (HCV) is the leading indication for liver transplantation in the United States. HCV recurrence after transplant is universal with several factors, including…2013 American Transplant Congress
Pancreas Transplant Outcomes May Be Dependent on Center Experience
Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis
Introduction: The number of pancreas transplants (PTx) nationwide is declining, raising concern that some centers may experience low transplant volume; low volume has been associated…2013 American Transplant Congress
Racial Differences and Income Disparities Are Associated with Worse Allograft and Death Outcomes in Kidney Transplant Recipients with Lupus Nephritis
Background: An analysis of income disparities and racial differences on renal transplant outcomes in recipients with lupus nephritis (LN) has not been reported.Methods: We identified…2013 American Transplant Congress
Change of Blood Pressure and Circadian Rhythm after Kidney Transplantation in End Stage Renal Disease Patients, The
BackgroundAfter kidney transplantation (KT), many end-stage renal disease (ESRD) patients showed well controlled blood pressure compared to before KT, but the effect of KT on…2013 American Transplant Congress
Renal Allograft Tolerance Can Be Achieved in Non-Human Primates Via Delayed Mixed-Hematopoietic Chimerism and Alefacept Treatment
Renal allograft tolerance has been achieved in MHC-mismatched NHPs and patients via the mixed-chimerism approach. Activation/expansion of donor-reactive CD8+ effector memory T cells (TEMs) represents…2013 American Transplant Congress
Antagonists of Bone Morphogenetic Protein Signaling Promote Liver Regeneration and Repair in Mice
The Transplant Center and Department of Surgery, Vanderbilt University Medical Center, Nashville, TN
Pharmacologic agents to enhance liver recovery after injury would have wide therapeutic application. Based on previous work suggesting Bone Morphogenetic Protein (BMP) signaling modulates liver…2013 American Transplant Congress
Dual Kidney Transplantation Reduces Organ Wastage and Increases the Number of Kidney Transplants Available to Elderly Candidates
Department of Transplantation, California Pacific Medical Center, San Francisco, CA
Changes in national kidney allocation are anticipated to begin in 2014. The proposed system redefines ECD kidneys, resulting in a reduction in both the quantity…2013 American Transplant Congress
Phase 3, Double-Blind, Multi-Center, Non-Inferiority, Randomized Study To Examine the Efficacy and Safety of LCP-Tacro™ Tablets, Once Daily, Compared to Prograf® Capsules, Twice Daily, in Combination with Mycophenolate Mofetil in De Novo Adult Kidney Transplantation: Baseline Characteristics, A
This large, multi-continent, Phase 3, double-blind, randomized, active comparator non-inferiority trial will compare efficacy and safety of a once-daily controlled agglomeration formulation of tacrolimus with…
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