2013 American Transplant Congress
Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 24
HERAKLES Study Group, Germany; Novartis Pharma, Nuremberg, Germany
Aim: To follow up (FU) on the evolution of renal function (RF) of immunosuppressive regimens with different calcineurin inhibitor (CNI) exposure at month (Mo)24 post…2013 American Transplant Congress
Kidney Discard Reasons by Kidney Donor Profile Index (KDPI)
KDPI summarizes the risk of donor kidney graft failure based on clinical and demographic parameters. We hypothesize that discard of a kidney with low KDPI…2013 American Transplant Congress
Single Donor-Derived Strongyloides in Solid Organ Transplants
Geisinger Medical Center, Danville; Temple University Hospital, Philadelphia
CDC was notified of Strongyloides infection in transplant recipients of kidneys, pancreas and heart from same deceased donor. Concern for donor-derived strongyloidiasis prompted an investigation…2013 American Transplant Congress
Donor Factors Similarly Impact Survival Outcome after LT in HCC and Non-HCC Patients
Introduction: Many have advocated the preferential use of high risk allografts for hepatocellular carcinoma (HCC) patients undergoing liver transplantation (LT). HCC patients tend to have…2013 American Transplant Congress
Glycemic Control Significantly Improves Graft & Patient Survival Following Liver Transplant for Hepatitis C
Pharmacy, MUSC, Charleston; Transplant, MUSC, Charleston, SC
Background: Hepatitis C (HCV) is the leading indication for liver transplant in the US. HCV recurrence after transplant is universal and metabolic abnormalities are common…2013 American Transplant Congress
Urinary Metabolomic Pattern Varies over Time and May Be Different in Patients Receiving Cyclosporine or Tacrolimus
EA4245, Université François Rabelais, Tours, France
The tools currently available for clinical monitoring of kidney graft dysfunction are not optimal. Metabolomics is a post-genomic application for analysis of low-molecular weight compounds,…2013 American Transplant Congress
Pre-Transplant Immunologic Risk Assessment and Immune Monitoring of Kidney Transplant Recipients with Pre-Transplant Donor-Specific Anti-HLA Antibodies
Montefiore-Einstein Center for Transplantation, Bronx, NY
Background: We aimed to investigate the importance of pre-transplant immunologic risk assessment of kidney transplant recipients with donor-specific anti-HLA antibodies (DSA) and immune monitoring of…2013 American Transplant Congress
Characterization of Human Monocyte Subsets
Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, Pittsburgh, PA
Monocytes are the dominant cell population infiltrating renal allografts early after transplantation, and monocyte-mediated graft dysfunction has been observed following T cell depletion. Monocytes have…2013 American Transplant Congress
In Vivo Depletion of CD8+ and αβTCR+ Cells Overcomes the Rejection of Vascularized Composite Tissue Allotransplant in Sensitized Recipients
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY
Sensitization, a state of the presence of donor-specific antibody (DSA) in recipient, has usually been considered an absolute contraindication to solid organ transplantation. Currently, the…2013 American Transplant Congress
Evaluation of Humoral (HI) & Cell-Mediated Immune (CMI) Responses to Trivalent Influenza Vaccine (TIV) Administered Early after Solid-Organ Transplantation (SOT)
Background: Vaccination earlier than 3 months post SOT is felt to be safe but data on vaccine efficacy in this setting is lacking. We evaluated…
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