ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Conversion from Tacrolimus to Sirolimus May Increase the Risk of Cardiovascular Events in Kidney Transplant Recipients

    M. Kim, M. Pavlakis, C. Rogers

    Beth Israel Deaconess Medical Center, Boston, MA

    Sirolimus (SRL) based immunosuppression regimens are used in kidney transplant recipients (KTRs) to avoid tacrolimus (TAC) toxicity. KTRs have a high risk of cardiovascular events…
  • 2013 American Transplant Congress

    Identification of Common Blood-Based Biomarker Gene Panels for the Diagnosis of Renal and Cardiac Acute Allograft Rejection

    S. Roedder, L. Li, K. Kush, S. Hsieh, H. Luikart, A. Yang, H. Valentine, M. Sarwal

    Transplantation Research, BIOMARC Program, California Pacific Medical Center, Sutter Health, San Francisco, CA; Cardiovascular Medicine, Department of Medicine, Stanford University, Palo Alto, CA

    To validate a peripheral blood transcriptional biomarker panel diagnostic for acute renal allograft rejection for the diagnosis and prediction of acute cardiac allograft rejection we…
  • 2013 American Transplant Congress

    Effective Federal Advocacy: The Case for HIV-Infected Deceased Organ Donors

    B. Boyarsky, K. Gebo, P. Stock, D. Segev

    Johns Hopkins, Baltimore; UCSF, San Francisco

    Background. HIV is no longer a contraindication to solid organ transplantation. For HIV-infected patients, HIV-infected deceased donors (HIVDD) could attenuate the organ shortage and waitlist…
  • 2013 American Transplant Congress

    Incidence of BKV after Kidney Transplantation with Tacrolimus (FK) Based Immunosuppression and Alemtuzumab Induction: A Retrospective Analysis of Donation after-Cardiac Death (DCD) vs. Donation after Brain Death (DBD)

    H. Lam, S. Li, V. Gunabushanam, A. Tevar, H. Tan, A. Basu, M. Sturdevant, A. Humar, J. McCauley, C. Wu, N. Shah, P. Sood, P. Randhawa, A. Zeevis, J. Lunz, R. Shapiro

    Abdominal Transplant Surgery, UPMC, Pittsburgh; Transplant Nephrology, UPMC, Pittsburgh; Transplant Pathology, UPMC, Pittsburgh

    Introduction: With increasing organ shortage, transplant centers are increasing the utilization of DCD organs. However, the incidence of BKV has not been well investigated when…
  • 2013 American Transplant Congress

    Gradual vs Rapid Withdrawal of Immunosuppression after Kidney Allograft Failure Results in Less Allosensitization, Decreased Rate of De-Novo Donor Specific Antibody and Reduced Need for Allograft Nephrectomy

    S. Rao, R. Bray, S. Perez, S. Pastan, H. Gebel, A. Chami

    Transplant Nephrology, Emory University Hospital, Atlanta, GA; Pathology and Laboratory Medicine, Emory University Hospital, Atlanta, GA; Deparment of Surgery, Emory University Hospital, Atlanta, GA

    Aim- Allosensitization after renal allograft failure is a major obstacle to re-transplantation.Withdrawal of immunosuppression after allograft failure is associated with sensitization. However, prolonged continuation of…
  • 2013 American Transplant Congress

    Comparable Risk of End-Stage Renal Disease (ESRD) in Liver Transplant Alone (LTA) and Simultaneous Liver Kidney (SLK) Recipients Who Had Pre-LT Kidney Biopsy for Renal Dysfunction or Proteinuria

    H. Wadei, M. Mai, M. Prendergast, A. Keaveny, S. Pungpapong, T. Gonwa

    Transplantation, Mayo Clinic, Jacksonville, FL

    Data concerning the utility of kidney biopsy in liver transplant (LT) candidates with renal dysfunction and/or proteinuria is lacking. Methods: 67 LT candidates with iothalamate…
  • 2013 American Transplant Congress

    Pulmonary Vascular Hemodynamics Improvement with Left Ventricular Assist Devices Unloading Is Sustained after Heart Transplantation

    A. Saidi, O. Wever-Pinzon, J. Stehlik, E. Gilbert, R. Alharethi, C. Selzman, B. Reid, D. Budge, A. Kfoury, F. Bader

    UTAH Cardiac Transplant Program, Salt Lake City, UT

    Background:Pulmonary hypertension (PHT) is frequently seen in patients with advanced heart failure (HF) awaiting heart transplantation (HTx). Severe PHT is a contraindication for HTx. Both…
  • 2013 American Transplant Congress

    Long-Term Persistence of Recipient MHC Class-II Antigen Following Allogeneic Bone Marrow Transplantation

    T. Brennan, L. Lin, Y. Yang

    Surgery, Duke University, Durham, NC; Medicine and Immunology, Duke University, Durham, NC

    Background: Following allogeneic bone marrow transplantation there is rapid replacement of host antigen presenting cells with donor antigen presenting cells. This has important implications of…
  • 2013 American Transplant Congress

    Sustained Expression of CD39 Protects Acutely from Renal IRI but Promotes Fibrosis

    V. Roberts, B. Lu, P. Cowan, S. Robson, K. Dwyer

    Immunology Research Centre, St Vincent's Hospital, Melbourne, Victoria, Australia; University of Melbourne, Melbourne, Victoria, Australia; Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, MA

    Background: The adenosinergic axis is involved in renal ischemia reperfusion injury (IRI) and the generation of adenosine by the action of CD39 and CD73 is…
  • 2013 American Transplant Congress

    Pegylated Interferon Maintenance Therapy for Recurrent Hepatitis C after Liver Transplantation

    C. Yazici, V. Maddukuri, G. Conner, M. Russo

    Hepatology, Carolinas Medical Center, Charlotte, NC

    Introduction: Recurrent hepatitis C (Hep C) is a major problem after liver transplantation. We analyzed our data on the virologic, biochemical and histological response with…
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