ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Cost Effectiveness of a Belatacept-Based Regimen in Kidney Transplant Recipients

    V. Caccioppoli, A. MacLasco, K. Chan, R. Gandhi, S. LaBella, L. Somers, C. Rogers

    Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA; Northeastern University, Bouve College of Pharmacy, Boston, MA

    Chronic use of calcineurin inhibitors has been associated with cardiovascular (CV) toxicity and nephrotoxicity in kidney transplant recipients (KTR). Belatacept (bela) is associated with lower…
  • 2013 American Transplant Congress

    Association of Brain Death Donor Cytokinemia with Donor and Recipient Renal Function in the Steroid Era

    A. Bongu, C. Mora-Esteves, A. Beidas, G. Dikdan, J. Oliver, S. Corti, J. Jalak, B. Koneru

    Surgery, UMDNJ-NJMS, Newark, NJ

    Brain death (BD) donor cytokinemia was associated with decreased organ recovery and worse post transplant outcomes before routine steroid use. Because steroids decrease cytokinemia in…
  • 2013 American Transplant Congress

    Proposed Surveillance Strategy for Hepatocellular Carcinoma Recurrence after Liver Transplantation, A

    D. Levi, M. Russo, K. Uchida, S. Nishida, A. Tzakis

    Transplant Center, Carolinas Medical Center, Charlotte, NC; Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL; Transplant Center, Cleveland Clinic Florida, Weston, FL

    Liver transplantation (LT) is indicated in cirrhotic patients with early, unresectable hepatocellular carcinoma (HCC). Post-transplant HCC recurrence, although uncommon, remains a serious problem. There are…
  • 2013 American Transplant Congress

    Outcomes of Kidney Transplants from DCD Donors Declined by the Primary Regional Centre

    E. Wlodek, D. Mallon, J. Bradley, G. Pettigrew

    Department of Surgery, Cambridge University, Cambridge, United Kingdom

    Introduction: The recent expansion in donation after circulatory death (DCD) kidney transplantation within the UK has raised questions regarding donor suitability, particularly relating to the…
  • 2013 American Transplant Congress

    Laparoscopic Sleeve Gastrectomy in Obese Renal Transplant Candidates

    T. Diwan, C. Freeman, R. Alloway, A. Rikes-Shields, G. Moglishetty, A. Govil, M. Cardi, R. Munda, S. Shah, M. Cuffy, F. Paterno, S. Woodle

    Division of Transplant Surgery, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Nephrology, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Nephrology, The Christ Hospital, Cincinnati, OH

    Dialysis is associated with high mortality, and obesity often precludes transplantation. Weight loss prior to transplantation may reduce the morbidity and mortality associated with transplantation.…
  • 2013 American Transplant Congress

    Comprehensive Analyses of Inhibitory Effects of the mTOR Inhibitor Everolimus on the Differentiation into Subsets of Human T-Helper Cells and B Cells

    Y. Tanaka, M. Yamashita, H. Ohdan

    Hiroshima University, Hiroshima, Japan

    [Aim] Although the various potential benefits of everolimus over other immunosuppressants in organ transplantation have been described, the precise sensitivity of this drug to differentiation…
  • 2013 American Transplant Congress

    Neutralization of IL-23 Is Protective Against Hepatic Cold Ischemia/Reperfusion (I/R) Injury

    J. Klune, S. Yokota, C. Bartels, N. Murase, Q. Du, D. Geller

    Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA

    Purpose: Interleukin-23 (IL-23) can activate inflammatory pathways such as CD4+ cell differentiation into IL-17 secreting Th17 cell type and increased production of IFNg leading to…
  • 2013 American Transplant Congress

    Pulmonary Hypertension Identified by Color Doppler Echocardiography in Renal Transplant Candidates: Prevalence and Effect on Survival

    A. Ribeiro, M. Gazzana, A. Vicari, M. Knorst, R. Manfro

    Nephrology Department, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; Pulmonology Departament, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

    Background: Pulmonary hypertension (PH) has been recognized frequently in patients with chronic renal failure undergoing hemodialysis. Some studies have suggested that PH may be associated…
  • 2013 American Transplant Congress

    Risk Factors, Rejection and Infections Associated with Neutropenia in Solid Organ Transplantation: A Retrospective Study

    S. Clairoux, M. Fournier, J. Amiel, M. Tremblay, D. Vinh, C. Coursol, D. Thirion, M. Cantarovich

    Department of Pharmacy, McGill University Health Center (MUHC), Montreal, Canada; Faculty of Pharmacy, University of Montreal, Montreal, Canada; Multi-Organ Transplant Program, MUHC, Montreal, Canada; Division of Infectious Diseases, MUHC, Montreal, Canada

    Introduction: Neutropenia is relatively frequent after solid organ transplantation (SOT). Its risk factors have been scarcely studied and its consequences remain to be defined in…
  • 2013 American Transplant Congress

    Jak3 Dependent Inhibition of Alloreactive T Cell Proliferation in the Setting of Chronic TLR Stimulation

    T. Brennan, L. Lin, Y. Yang

    Surgery, Duke University, Durham, NC; Medicine and Immunology, Duke University, Durham, NC

    Background: Maturation of dendritic cells (DCs) by a pulse TLR ligands increases their antigen presentation efficacy and leads to increased proliferation of T cells in…
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