2013 American Transplant Congress
Prospective and Randomized Trial Comparing Tacrolimus Versus Sirolimus after Simultaneous Pancreas-Kidney Transplantation
Institut de Transplantation-Urologie-Néphrologie, Nantes University Hospital, Nantes, France
Introduction. Minimizing or sparing potentially nephrotoxic and diabetogenic immunosuppressants could represent an advantage following simultaneous pancreas-kidney transplantation (SPK-Tx).Purpose. We report here the actual one-year result…2013 American Transplant Congress
Variability of IMPDH-Activity in Long-Term MPA Mediated Immunosuppression
Purpose of this study was to examine wether the long term exposure for mycophenolate mofetil (MMF) or enteric coated form (EC-MPS) is leading to an…2013 American Transplant Congress
Suppression of Acute Rejection by Administration of Prostaglandin E2 Receptor Subtype 4 (EP4) Agonist in a Rat Heterotopic Small Bowel Transplantation Model
Background: Prostaglandin E2 (PGE2)–PGE2 receptor subtype 4 (EP4) signaling is known to modulate the inflammation process. Several studies have demonstrated the potential utility of EP4-selective…2013 American Transplant Congress
Kidney Injury Molecule-1 and Osteopontin: New Markers for Prediction of Early Kidney Transplant Rejection
Background. Kidney injury molecule-1 (KIM-1) and osteopontin (OPN) play important roles in immune regulation. We hypothesized that serum KIM-1 and OPN might serve as biomarkers…2013 American Transplant Congress
Health-Related Quality of Life and Adherence to Medication in Kidney Transplantation: A Longitudinal Analysis
AimTo analyse the influence of dialysis type on adherence to immunosupressive medications (IS) and HRQoL before and after KT.Material and Methods. Between years 2004-2008 156…2013 American Transplant Congress
Impact of Vitamin D, Bisphosphonate, and Combination Therapy on Bone Mineral Density in Kidney Transplant Patients
Background: Osteoporosis can develop and become aggravated in a large number of kidney transplant patients; however, the best preventive options for post-transplant osteoporosis remain controversial.Methods:…2013 American Transplant Congress
IL-1 Receptor Antagonist Treatment Rescues Impact of Brain Death Related Inflammation in Liver of Non-Human Primates
University of Wisconsin, Madison
Donor liver quality is critical to avoid primary non-function or dysfunction after transplantation. Previously, our lab developed a model of Non-human Primate (NHP) Brain death…2013 American Transplant Congress
MFI TRAP: HLAmatchmaker Can Help To Do the Reactions Patterns of DSA Versus NDSA To Assess Risk of Graft Failure by AMR, THE
The HLAMatchmaker (HLAMM) evaluates the compatibility between donor and recipient through comparisons within and between loci, and determines which epitopes in HLA mismatched are different…2013 American Transplant Congress
Activated T Regulatory Cells Escape Death by Increasing Cytoplasmic Serine Protease Inhibitor 6 (SPI6)
Medicine, Harvard Medical School, Boston
Regulatory T cells (Tregs) can employ a granzyme B (GrB)-dependent mechanism to mediate suppression of effector cells by inducing their apoptosis. Herein, we show that…2013 American Transplant Congress
Glomerular microRNA Expression Profiles in Transplant-Associated Thrombotic Microangiopathy
Thrombotic microangiopathy is a serious complication of renal transplantation. Besides recurrence of the primary disease (RecTMA) renal transplant-associated thrombotic microangiopathy (rTx-TMA) can emerge de novo…
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