2013 American Transplant Congress
Thymoglobulin Is Associated with a Significant Reduction in De Novo Donor-Specific Antibodies and Antibody Mediated Rejection in Moderately Sensitized Renal Transplant Recipients
University of Wisconsin, Madison, WI
De novo donor specific antibodies (dnDSA) are associated with antibody mediated rejection (ABMR) and graft failure following kidney transplantation. The impact of induction immunosuppression on…2013 American Transplant Congress
Quality of Life Outcomes Reported in Randomized Controlled Trials of Immunosuppressive Drug Regimens in Kidney Transplantation:
Background: The evaluation and selection of immunosuppressive drug regimens in kidney transplantation is increasingly focussed on long term patient and graft survival. An understanding of…2013 American Transplant Congress
IL-33: Friend or Foe?
Introduction We hypothesize that innate inflammatory response either preexistent in the recipient or released by injured allografts during transplantation may influence graft outcome. In a…2013 American Transplant Congress
Effects of Everolimus and Tacrolimus Exposure on Efficacy and Renal Function in Liver Transplant Recipients at 24 Months in a Randomized Trial (H2304)
For the H2304 Study Group, Hamburg, Germany; Novartis Pharma AG, Basel, Switzerland
Purpose: The present analysis aims to explore the effect of everolimus (EVR) and tacrolimus (TAC) exposure on efficacy and safety events of interest in de…2013 American Transplant Congress
Everolimus-Facilitated Reduction of Tacrolimus in De Novo Liver Transplant Recipients Achieves Comparable Overall Efficacy with Fewer Biopsy-Proven Acute Rejections Versus Standard Tacrolimus: 24-Month Results of a Randomized Trial
Purpose: The H2304 (NCT00622869) study compared the efficacy and safety of concentration-controlled everolimus (EVR) to eliminate or to reduce tacrolimus (TAC) vs standard TAC (TAC-C)…2013 American Transplant Congress
Lack of Clinical Factors Increasing Quantitative Interstitial Fibrosis after Renal Transplantation under a Lower Target Trough Strategy of Tacrolimus
INTRODUCTION AND OBJECTIVES: Chronic allograft injury is a multi-factorial process based on immunologic and non-immunologic factors. Patients with the CYP3A5*3/*3 genotype (non-expressers) require a lower…2013 American Transplant Congress
Prospective and Randomized Trial Comparing Tacrolimus Versus Sirolimus after Simultaneous Pancreas-Kidney Transplantation
Institut de Transplantation-Urologie-Néphrologie, Nantes University Hospital, Nantes, France
Introduction. Minimizing or sparing potentially nephrotoxic and diabetogenic immunosuppressants could represent an advantage following simultaneous pancreas-kidney transplantation (SPK-Tx).Purpose. We report here the actual one-year result…2013 American Transplant Congress
Variability of IMPDH-Activity in Long-Term MPA Mediated Immunosuppression
Purpose of this study was to examine wether the long term exposure for mycophenolate mofetil (MMF) or enteric coated form (EC-MPS) is leading to an…2013 American Transplant Congress
Comparison of Transumbilical and Conventional Laparoscopic Donor Nephrectomy
Forty-eight healthy voluntary renal donors between 18 and 60 years of age with BMI less than 30 who were planned for laparoscopic left side donor…2013 American Transplant Congress
Liver Transplantation: Do Senescence and Autophagy Modulate the Development of Chronic Pathology
During the past 20 years there has been a reduction in the incidence of both acute cellular rejection (ACR) and chronic ductopenic rejection following liver…
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