2013 American Transplant Congress
Therapeutic Mycophenolic Acid Area-Under-Curve (MPA AUC) Levels Abolish Donor-Specific Antibody Formation in Established and De Novo Renal Transplant Patients
PinnacleHealth Transplantation, Harrisburg, PA
Background: Donor-specific antibody (DSA) formation is a key factor in development of antibody-mediated rejection and irreversible renal dysfunction. Prevention of DSA formation is critical, mandating…2013 American Transplant Congress
Minimization of Immunosuppression for ABO-Incompatible Kidney Transplantation Based on the Strength of Pretreatment Anti A/B Antibody Titer
Acute antibody mediated rejection (AMR) used to be a major problem in ABO-incompatible KidneyTransplantation (ABOi-KTx), and currently rituximab has been accepted to reduce the prevalence…2013 American Transplant Congress
Conversion from Tacrolimus to Sirolimus May Increase the Risk of Cardiovascular Events in Kidney Transplant Recipients
Beth Israel Deaconess Medical Center, Boston, MA
Sirolimus (SRL) based immunosuppression regimens are used in kidney transplant recipients (KTRs) to avoid tacrolimus (TAC) toxicity. KTRs have a high risk of cardiovascular events…2013 American Transplant Congress
Identification of Common Blood-Based Biomarker Gene Panels for the Diagnosis of Renal and Cardiac Acute Allograft Rejection
To validate a peripheral blood transcriptional biomarker panel diagnostic for acute renal allograft rejection for the diagnosis and prediction of acute cardiac allograft rejection we…2013 American Transplant Congress
Effective Federal Advocacy: The Case for HIV-Infected Deceased Organ Donors
Johns Hopkins, Baltimore; UCSF, San Francisco
Background. HIV is no longer a contraindication to solid organ transplantation. For HIV-infected patients, HIV-infected deceased donors (HIVDD) could attenuate the organ shortage and waitlist…2013 American Transplant Congress
Incidence of BKV after Kidney Transplantation with Tacrolimus (FK) Based Immunosuppression and Alemtuzumab Induction: A Retrospective Analysis of Donation after-Cardiac Death (DCD) vs. Donation after Brain Death (DBD)
Introduction: With increasing organ shortage, transplant centers are increasing the utilization of DCD organs. However, the incidence of BKV has not been well investigated when…2013 American Transplant Congress
Gradual vs Rapid Withdrawal of Immunosuppression after Kidney Allograft Failure Results in Less Allosensitization, Decreased Rate of De-Novo Donor Specific Antibody and Reduced Need for Allograft Nephrectomy
Aim- Allosensitization after renal allograft failure is a major obstacle to re-transplantation.Withdrawal of immunosuppression after allograft failure is associated with sensitization. However, prolonged continuation of…2013 American Transplant Congress
Comparable Risk of End-Stage Renal Disease (ESRD) in Liver Transplant Alone (LTA) and Simultaneous Liver Kidney (SLK) Recipients Who Had Pre-LT Kidney Biopsy for Renal Dysfunction or Proteinuria
Transplantation, Mayo Clinic, Jacksonville, FL
Data concerning the utility of kidney biopsy in liver transplant (LT) candidates with renal dysfunction and/or proteinuria is lacking. Methods: 67 LT candidates with iothalamate…2013 American Transplant Congress
Plasma Soluble IL-6 Receptor (SIL-6R) Levels Are Significantly Elevated during Antibody-Mediated Rejection (ABMR) in Highly-HLA Sensitized Renal Allograft Recipients (HS Pts)
Medicine, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles, CA
Background: ABMR episodes involve multiple immunologic and inflammatory pathways. IL-6/IL-6R interactions have pleiotropic effects on immunity and inflammation and may have relevance to ABMR. Recent…2013 American Transplant Congress
Pancreas Re-Transplantation Graft Survival Is Comparable to Primary Pancreas after Kidney Transplantation
Background: Reports on the outcomes of pancreas re-transplantation are scarce in the modern era. We compared the outcome of pancreas re-transplantation with primary pancreas after…
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