2013 American Transplant Congress
Ventricular Assist Devices Are Associated with HLA but NOT MICA Allosensitization
Cleveland Clinic, Cleveland; Baylor Univeristy, Dallas
Ventricular assist device (VAD) is implicated in HLA-sensitization. We investigate the association between VAD and HLA & MICA sensitization.Of all VAD patients studied (00-09); 89…2013 American Transplant Congress
Oral Ribavirin Therapy for Respiratory Syncytial Virus Infections in Moderately to Severely Immunocompromised Patients
BackgroundRespiratory syncytial virus (RSV) can be fatal in immunocompromised patients. Aerosolized ribavirin is used for treatment but it is costly, teratogenic, and inconvenient. We aimed…2013 American Transplant Congress
Utilization of Kidneys from Donors after Circulatory Death in China: An Initial Report from a Single Center
In 2007, a landmark decision that is supported by the international transplant community, the Chinese national government has established regulations to gradually abolish the use…2013 American Transplant Congress
Outcomes of Switching to Belatacept from a Calcineurin Inhibitor in Kidney Transplant Recipients: 3 Year Results from the Long-Term Extension of a Phase II Study
Introduction: There remains a need for immunosuppressive agents which offer long-term preservation of renal function and an acceptable safety profile in the switch setting. Here…2013 American Transplant Congress
Polyoma BK-Virus-Specific T Cells as a Surrogate Marker for Polyomavirus-Associated Nephropathy after Pediatric Kidney Transplantation
After kidney transplantation (KTx) immunosuppressive therapy causes impaired cellular immune defense resulting in increased risk of polyomavirus-associated nephropathy (PVAN). Prognostic markers for the outcome of…2013 American Transplant Congress
Rat Liver Allo-Graft Rejection Promotes Anti-Cancer Immunity: A Model of Transplantation for Hepatocellular Carcinoma
Background: Liver transplantation for hepatocellular carcinoma (HCC) results in a specific condition where the immune response is directed both against allogeneic and cancer antigens. This…2013 American Transplant Congress
Morphometric Age as a Predictor of Post Liver Transplant Survival
General Surgery, Division of Transplant Surgery, University of Michigan, Ann Arbor
INTRODUCTION: Better measures of pre-operative risk stratification are needed in liver transplantation. A cornerstone of a surgeon’s clinical assessment is best described as the “eyeball…2013 American Transplant Congress
Natural Regulatory T-Cells Impair the Donor-Specific Cytotoxic T-Cell Response Long after Transplantation
Internal Medicine - Transplantation, Erasmus MC, Rotterdam, Netherlands
Introduction: CD4+CD25highCD127- are potent regulators of cytokine production and proliferation of alloreactive T-cells. Although, cytotoxic T-cells are the effector cells that destroy the allograft. The…2013 American Transplant Congress
Cigarette Smoking in Living Kidney Donors and Graft Survival
General Surgery, Division of Transplant Surgery, University of Michigan, Ann Arbor, MI
Background: The deleterious effects of cigarette smoking contribute to a number of significant health-related problems but the effect of donor smoking history on kidney graft…2013 American Transplant Congress
Risk of Transmission of Cancer from Solid Organ Donors in the U.S
National Cancer Institute, Rockville, MD
Background: Transmission (TX) of cancer is a rare but life-threatening complication of transplantation. Most cancers preclude donation, but some may be missed if an accurate…
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