2013 American Transplant Congress
Acute Rejection in Older Kidney Transplant Recipients
Johns Hopkins University School of Medicine, Baltimore, MD
BACKGROUND: Age limits for transplantation have expanded significantly in the last 20 years, with a 5-fold increase in the number of older adults receiving kidney…2013 American Transplant Congress
Th17 Memory Cells Are More Dependent on Coinhibition by CTLA-4 Than Th1 Memory Cells and Are Associated with Rejection in Patients Treated with Belatacept
Emory Transplant Center, Atlanta, GA
T cell memory is comprised of an assortment of phenotypic lineages suited for microbial immunity that may cross-react with allogeneic antigens to drive pathological immune…2013 American Transplant Congress
Extended Criteria Donor (ECD) Renal Allograft Use in Older Recipients in a Short Wait Time Center: Is There an Advantage?
Surgery, Univeristy of Florida, Gainesville, FL; Medicine, Univeristy of Florida, Gainesville, FL
Merion et al. (JAMA, 2005) concluded that ECD renal grafts benefit a recipient if they are older than 40 with hypertension or diabetes, and have…2013 American Transplant Congress
TOL101 Signaling Pathways, a Novel CD3 Independent T Cell Inactivation & Treg Induction Cascade
In a Phase 2 renal transplant study, the anti-ΑΒ TCR antibody TOL101 inhibited T cell function in transplant patients at a range of doses. When…2013 American Transplant Congress
Living Donor Kidney Transplantation in the Pediatric Population: Risk Factors for Adverse Outcomes
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Purpose: To review the pediatric recipients of laparoscopic donor nephrectomy (LDN) at our institution and examine predictors of adverse outcomes, particularly in patients ≤5 years…2013 American Transplant Congress
Living Donor Liver Transplantation for High MELD Score Patients
Background: Liver transplantation is the only effective treatment for the very sick liver failure patients. For the success of liver transplantation, it is better to…2013 American Transplant Congress
Does an Isolated Positive B-Cell Crossmatch Carry Prognostic Information in Pediatric Heart Transplantation?
Cardiology, Boston Children's Hospital, Boston, MA
BACKGROUND: Recent data suggest that a positive T-cell crossmatch (CM) is associated with reduced post-heart transplant survival in children. An isolated positive B-cell flow crossmatch…2013 American Transplant Congress
Infection Related Kidney Discards
Background: Despite a long wait-list, transplant physicians always weigh the benefit of transplantation against the risk of accepting a potentially infected solid organ with resultant…2013 American Transplant Congress
Non-Invasive Imaging of Acute Allograft Rejection by Ultrasound Detection of Microbubbles Targeted to T-Lymphocytes in a Rat Renal Transplantation Model
ObjectiveWe propose anti-CD3-antibody-mediated contrast-enhanced ultrasonography using human T-lymphocytes for image-based diagnosis and differentiation of acute allograft rejection (AR) established in a rat renal transplantation model.MethodsAfter…2013 American Transplant Congress
Lower Serum Magnesium 1-Year Posttranplantation Is Associated with Decreased Graft Survival in Renal Transplant Recipients
Hypomagnesaemia is a known side effect of immunosuppressive regimen, especially calcineurin inhibitors, and has been associated with new onset diabetes after transplantation (NODAT), decreased graft…
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