2013 American Transplant Congress
Th17 Memory Cells Are More Dependent on Coinhibition by CTLA-4 Than Th1 Memory Cells and Are Associated with Rejection in Patients Treated with Belatacept
Emory Transplant Center, Atlanta, GA
T cell memory is comprised of an assortment of phenotypic lineages suited for microbial immunity that may cross-react with allogeneic antigens to drive pathological immune…2013 American Transplant Congress
Extended Criteria Donor (ECD) Renal Allograft Use in Older Recipients in a Short Wait Time Center: Is There an Advantage?
Surgery, Univeristy of Florida, Gainesville, FL; Medicine, Univeristy of Florida, Gainesville, FL
Merion et al. (JAMA, 2005) concluded that ECD renal grafts benefit a recipient if they are older than 40 with hypertension or diabetes, and have…2013 American Transplant Congress
TOL101 Signaling Pathways, a Novel CD3 Independent T Cell Inactivation & Treg Induction Cascade
In a Phase 2 renal transplant study, the anti-ΑΒ TCR antibody TOL101 inhibited T cell function in transplant patients at a range of doses. When…2013 American Transplant Congress
Living Donor Kidney Transplantation in the Pediatric Population: Risk Factors for Adverse Outcomes
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Purpose: To review the pediatric recipients of laparoscopic donor nephrectomy (LDN) at our institution and examine predictors of adverse outcomes, particularly in patients ≤5 years…2013 American Transplant Congress
Living Donor Liver Transplantation for High MELD Score Patients
Background: Liver transplantation is the only effective treatment for the very sick liver failure patients. For the success of liver transplantation, it is better to…2013 American Transplant Congress
Incidence, Risk Factors and Outcomes of BK Viremia and Nephropathy Following Kidney, Simultaneous Kidney-Pancreas or Pancreas after Kidney Transplant
University of Wisconsin Hospital, Madison, WI
We examined the incidence and risk factors for BK viremia and nephropathy (BKV and BKN) and their impact on graft survival in kidney, simultaneous kidney-pancreas…2013 American Transplant Congress
Plasma Soluble IL-6 Receptor (SIL-6R) Levels Are Significantly Elevated during Antibody-Mediated Rejection (ABMR) in Highly-HLA Sensitized Renal Allograft Recipients (HS Pts)
Medicine, Cedars-Sinai Medical Center/UCLA School of Medicine, Los Angeles, CA
Background: ABMR episodes involve multiple immunologic and inflammatory pathways. IL-6/IL-6R interactions have pleiotropic effects on immunity and inflammation and may have relevance to ABMR. Recent…2013 American Transplant Congress
Pancreas Re-Transplantation Graft Survival Is Comparable to Primary Pancreas after Kidney Transplantation
Background: Reports on the outcomes of pancreas re-transplantation are scarce in the modern era. We compared the outcome of pancreas re-transplantation with primary pancreas after…2013 American Transplant Congress
Cost Effectiveness of a Belatacept-Based Regimen in Kidney Transplant Recipients
Chronic use of calcineurin inhibitors has been associated with cardiovascular (CV) toxicity and nephrotoxicity in kidney transplant recipients (KTR). Belatacept (bela) is associated with lower…2013 American Transplant Congress
Association of Brain Death Donor Cytokinemia with Donor and Recipient Renal Function in the Steroid Era
Surgery, UMDNJ-NJMS, Newark, NJ
Brain death (BD) donor cytokinemia was associated with decreased organ recovery and worse post transplant outcomes before routine steroid use. Because steroids decrease cytokinemia in…
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