ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Excellent Outcomes with Transplantation of Kidneys (KTx) from Deceased Donors (DDs) with Acute Kidney Injury (AKI)

    C. Santhanakrishnan, A. De Mattos, J. McVicar, R. Perez, C. Troppmann

    Division of Transplantation, Dept of Surgery, University of California Davis Medical Center, Sacramento, CA

    Background:AKI is common among DDs and results in high discard rates. In contrast, we have consistently used kidneys from DDs with AKI. We studied our…
  • 2013 American Transplant Congress

    Quantitative Relationship of Luminex Single Antigen Bead Assay (LSA), Antibody Titration and Flow Crossmatch in Heart Transplantation – A Data Analysis of 5 Years Clinical Testing

    L. Wan, D. Chen

    Clinical Transplantation Immunology Lab, Duke University Medical Center, Durham, NC

    Donor selecting avoiding unacceptable HLA antigens (UAs) efficiently facilities heart transplant without performing a final flow crossmatch (FCXM) prior to transplant. Luminex single antigen bead…
  • 2013 American Transplant Congress

    Inequitable Access to Deceased Donor Kidney Transplantation (KTx) in a State with Multiple Donor Service Areas (DSAs)

    R. Lewis, A. Sankar, J. Pittman

    North Austin Medical Center, Austin, TX

    INTRO: Inequities (ineqs) in access to KTx date from the inception of the nationalized allocation system and remain a serious problem. The present study examines…
  • 2013 American Transplant Congress

    Molecular Landscape of T Cell-Mediated Rejection: The T Cell Synapse Emerges, The

    J. Venner, K. Famulski, P. Halloran

    University of Alberta, Edmonton, Canada

    The molecular landscape of T cell-mediated rejection (TCMR) is obscured by secondary inflammation and injury. We hypothesized the transcripts most highly associated with TCMR would…
  • 2013 American Transplant Congress

    Should Repeat HLA Mismatches Be Avoided in Lung ReTransplants?

    M. Askar, P. Reville, J. Daghstani, L. Klingman, K. McCurry, M. Budev

    Cleveland Clinic, Cleveland, OH

    De Novo DSA is associated with increased risk of Bronchiolitis Obliterans Syndrome (BOS) and lung allograft loss, however the characteristics of De Novo DSA that…
  • 2013 American Transplant Congress

    Correlations of In Vitro Islet Potency Tests with Clinical Islet Auto-Transplant Outcome

    K. Papas, M. Bellin, D. Sutherland, J. Kitzmann, E. Avgoustiniatos, A. Gruessner, K. Mueller, A. Balamurugan, P. Rozak, G. Loganathan, T. Suszynski, J. Wilhem, D. Qian, J. Niland, B. Hering

    Surgery, University of Arizona, Tucson, AZ; Surgery, University of Minnesota, Minneapolis, MN; Schulze Diabetes Institute, Minneapolis, MN; Information Science, City of Hope, Duarte, CA

    There is a critical need for real-time in vitro islet characterization assays that are predictive of clinical transplant outcomes (CTO), but none is available so…
  • 2013 American Transplant Congress

    Long Term Outcomes of Incidentally Discovered Hepatocellular Carcinoma

    K. Thudi, A. Humar, A. Tevar, M. Gajendran, S. Malik

    Gastroenterology and Hepatology; Transplant Surgery; Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA

    Background: The risk of hepatocellular carcinoma (HCC) is increased in patients with cirrhosis as a result of any chronic liver disease. Current guidelines recommend HCC…
  • 2013 American Transplant Congress

    Abrogation of Chronic Rejection Involves Down Regulation of mTOR/Rac1 Pathway

    M. Kloc, N. Tejpal, J. You, J. Sidhu, M. Ganachari, L. Zhang, R. Ghobrial

    Surgery, The Methidst Hospital and The Methodist Hospital Research Institute, Houston, TX

    Background: Chronic rejection is the major obstacle to long-term survival of organ allografts. We study the cellular and molecular pathways involved in the inhibition of…
  • 2013 American Transplant Congress

    IGL-1 Solution Prevents Proteolysis during Cold Steatotic Liver Graft Preservation

    M. Zaouali, M. Bejaoui, J. Garcia, A. Ribes, E. Pantazi, E. Folch, H. Abdennebi, J. Roselló-Catafau

    Experimental Pathology, Institute of Biomedical Research, Barcelona, Spain; Hospital Clinic, Barcelona, Spain; Human Physiology, Faculty of Pharmacy, Monastir, Tunisia

    Antecedents: Liver transplantation remains the sole therapy for a certain number of liver diseases at end stage. Liver proteolysis that occurs during cold storage influences…
  • 2013 American Transplant Congress

    Polymorphisms in the Transcription Factor NFATc4 Gene Are Associated with BKVN in Renal Allograft Recipients

    D. Vu, T. Shah, Y. Qazi, R. Naraghi, B. Kawewat, I. Hutchinson, D. Min

    National Institute of Transplantation, Los Angeles, CA; St. Vincent Medical Center, Los Angeles, CA; Western University of Health Sciences, Pomona, CA; University of Southern California, Los Angeles, CA; Transplant Research Institute, Los Angeles

    Background: BK virus nephropathy (BKVN) is a common viral infection that affects up to 10% of renal transplant recipients (RTRs), causing allograft dysfunction and graft…
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