2013 American Transplant Congress
Survival Benefit of Deceased Donor Transplantation with High-KDPI Kidneys
Johns Hopkins School of Medicine, Baltimore, MD
The Kidney Donor Profile Index (KDPI) was recently introduced as a metric for quality of DD kidneys. The survival benefit of transplantation with high-KDPI kidneys…2013 American Transplant Congress
Comparing Outcomes from Pancreata from Donation after Circulatory Death to Donation after Brain Death in a Small Rural Program
Background: Providing access to pancreas transplant in a rural center with an aging population and low crime rate can be challenging. However, the patients served…2013 American Transplant Congress
Features of Antibody-Mediated Rejection (AMR) in Early and Late Protocol and Indication Renal Allograft Biopsies
Depts of Medicine, ; Pathology, ; Surgery, University of Maryland, Baltimore, MD
The prevalence of serologic and histologic features of AMR in early and late biopsies and in association with graft fuction has not been well-recognized. We…2013 American Transplant Congress
Interpreting Macrophage Transcripts in T Cell-Mediated Rejection in Humans
The recently published model for T cell-mediated rejection (TCMR) of kidney allografts proposes that the major unit of cognate recognition in TCMR is effector T…2013 American Transplant Congress
Reduced Health Literacy in Kidney Transplant Recipients May Be Associated with Difficulty Identifying a Live Kidney Donor
Introduction: Health literacy (HL) may be a mediator for known socioeconomic (SES) and racial disparities in live kidney donation and provide a target for interventions…2013 American Transplant Congress
Differing Characteristics of New-Onset Diabetes after Transplantation (NODAT) in African-American Compared to Non-African-American Kidney Recipients
Hospital of the University of Pennsylvania, Philadelphia, PA
Background: NODAT, a common 1st post-transplant year complication, is more prevalent in African-American recipients (AA). Risk factors for, and the clinical course of NODAT are…2013 American Transplant Congress
MicroRNA 194 Regulates Apoptosis in Epstein Barr Virus+ B Cell Lymphomas Associated with Post-Transplant Lymphoproliferative Disorder
Surgery, Stanford University School of Medicine, Stanford, CA
Post-Transplant Lymphoproliferative Disease (PTLD) is a potentially fatal side effect of the immunosuppressive agents used to prevent allograft rejection. PTLD is associated with Epstein-Barr Virus…2013 American Transplant Congress
Inhibition of IL6 Mediated Th17 Differentiation Via BATF Signaling Prevents the Development of Obliterative Airway Disease Induced by Antibodies to MHC Molecules
Surgery, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
Background: Development of donor specific antibodies has been shown to precede the development of chronic rejection, bronchiolitis obliterans syndroms (BOS) following human lung transplantation. Using…2013 American Transplant Congress
Kidney Transplant Graft Loss – Continued Room for Improvement
Identification of causes of graft loss (GL)allows targeted preventive therapies. We studied actuarial GL in 5 decades (1960-2010), for adult 1st kidney tx recips. Donor…2013 American Transplant Congress
Indirect CD4 T Cell Allorecognition of MHC Class II Alloantigen Is Limited by Adaptive Immunity
Surgery, Cambridge University, Cambridge, United Kingdom
IntroductionWe have previously described a partially-mismatched [bm12.Kd.IE (IAbm12, IEd, Kd, Kb, Db) to C57BL/6] model of chronic cardiac allograft rejection, and demonstrated surprisingly that indirect…
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