2013 American Transplant Congress
How Should We Allocate Pediatric Deceased Donor Kidneys?
University of Chicago, Chicago, IL
Background: Pediatric deceased donor kidneys (DDK) are an important source of organs for kidney transplantation although there is no consensus about 1) which candidates are…2013 American Transplant Congress
Effect of Goal Tacrolimus Levels on Renal Function over Five Years Post-Transplant
Purpose: The adverse effect of tacrolimus on renal function is well documented and lower goal levels are presumed to lead to superior renal outcomes. However…2013 American Transplant Congress
Molecular Landscape of Antibody-Mediated Rejection: Reading Endothelial Cell Biology in the Microcirculation, The
University of Alberta, Edmonton, Canada
Because experimental models are lacking, the recent emergence of a molecular definition of antibody-mediated rejection (ABMR) presents opportunities to characterize the mechanisms operating in ABMR.…2013 American Transplant Congress
Association between De Novo Post-Transplant Nonmelanoma Skin Cancer and Solid Tumor after Solid Organ Transplantation – An Analysis of OPTN/UNOS Data
Mendez National Institute of Transplantation, LA, CA; USC School of Medicine, LA, CA
Backgrounds. Incidences of skin cancer and solid tumor among solid organ transplant recipients are significantly higher than those of immunocompetent persons. Nonmelanoma skin cancer (NMSC),…2013 American Transplant Congress
Hepatitis C Recurrence (HCVR) in Liver Transplant Recipients (OLT): Significant Reduction in Tacrolimus (FK) Dosage Can Be Safely Achieved in Patients Rendered Aviremic after Response-Guided Therapy (RGRx) Using Telaprevir (TVR)
The Liver Institute, Methodist Dallas Medical Center, Dallas, TX
Background: Allografts of viremic OLT are at high risk of dysfunction and failure. Conventional Rx outcomes with Pegylated interferon (P-IFN) + Ribavirin (RBV) are suboptimal.…2013 American Transplant Congress
Autosomal Dominant Polycystic Kidney Disease (PKD) Evaluated for Renal Transplantation. A Single Center Experience at Emory Transplant Center
Department of Nephrology, Emory University Hospital, Atlanta, GA
PKD is the fourth cause of ESRD and accounts for 13% of yearly kidney transplants in the US. Our goal is to use an established…2013 American Transplant Congress
YAP Phosphorylation Is Altered during Liver Regeneration in a Rat Hepatectomy Model
Purpose:The transcription factor YAP has been shown to stimulate hepatocyte proliferation. Furthermore, overexpression of YAP results in liver overgrowth leading to transformation into malignancy. Phosphorylation…2013 American Transplant Congress
Blockade of Phagocytosis Accelerates Cardiac Allograft Rejection
Transplantation Research Center, Brigham&Women's Hospital, Boston, MA
Under physiological conditions, prompt clearance of dying cells provides protection from the release of pro-inflammatory contents, induces T cell tolerance to self-antigens and prevents autoimmunity.…2013 American Transplant Congress
Central Role of Mitochondrial Energy Metabolism in Foxp3+ Treg Cell Function and Allograft Survival
Increasing Foxp3+ regulatory T-cell (Treg) numbers and/or their function are innovative approaches to immunosuppression post-transplantation. T-effector (TE) and Treg cells have differing metabolic needs, but…2013 American Transplant Congress
Long-Term Outcomes of Older Adults after Liver Transplantation in the MELD Era
Since 2002, MELD score has been the basis of liver allocation system. Among older adult liver transplant (LT) recipients, short-term outcomes in MELD era were…
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