ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Inequitable Access to Deceased Donor Kidney Transplantation (KTx) in a State with Multiple Donor Service Areas (DSAs)

    R. Lewis, A. Sankar, J. Pittman

    North Austin Medical Center, Austin, TX

    INTRO: Inequities (ineqs) in access to KTx date from the inception of the nationalized allocation system and remain a serious problem. The present study examines…
  • 2013 American Transplant Congress

    Molecular Landscape of T Cell-Mediated Rejection: The T Cell Synapse Emerges, The

    J. Venner, K. Famulski, P. Halloran

    University of Alberta, Edmonton, Canada

    The molecular landscape of T cell-mediated rejection (TCMR) is obscured by secondary inflammation and injury. We hypothesized the transcripts most highly associated with TCMR would…
  • 2013 American Transplant Congress

    Should Repeat HLA Mismatches Be Avoided in Lung ReTransplants?

    M. Askar, P. Reville, J. Daghstani, L. Klingman, K. McCurry, M. Budev

    Cleveland Clinic, Cleveland, OH

    De Novo DSA is associated with increased risk of Bronchiolitis Obliterans Syndrome (BOS) and lung allograft loss, however the characteristics of De Novo DSA that…
  • 2013 American Transplant Congress

    Correlations of In Vitro Islet Potency Tests with Clinical Islet Auto-Transplant Outcome

    K. Papas, M. Bellin, D. Sutherland, J. Kitzmann, E. Avgoustiniatos, A. Gruessner, K. Mueller, A. Balamurugan, P. Rozak, G. Loganathan, T. Suszynski, J. Wilhem, D. Qian, J. Niland, B. Hering

    Surgery, University of Arizona, Tucson, AZ; Surgery, University of Minnesota, Minneapolis, MN; Schulze Diabetes Institute, Minneapolis, MN; Information Science, City of Hope, Duarte, CA

    There is a critical need for real-time in vitro islet characterization assays that are predictive of clinical transplant outcomes (CTO), but none is available so…
  • 2013 American Transplant Congress

    Association of HLA-A, B, C, DR, and DQ Matching with Rejection and Survival in Pancreas Transplantation

    E. Finger, D. Radosevich, T. Dunn, A. Kukla, J. Lohlun, D. Sutherland, T. Pruett, R. Kandaswamy

    University of Minnesota, Minneapolis, MN

    Objective: Determine the impact of HLA matching on acute cellular rejection (ACR), and graft and patient survival in pancreas txp.Methods: Retrospective review of 1,063 sequential…
  • 2013 American Transplant Congress

    Protection from Prolonged Cold Ischemia (CI) of Several Days Duration Is Mediated by Anti-Apoptotic phosphoBAD during Hibernation

    A. Jani, S. Jain, T. Nydam, C. Edelstein

    UCDenver, Denver, CO

    Donor kidney cold (4°C) ischemia (CI) of >30 hrs is associated with increased apoptosis of renal tubular epithelial cells (RTEC) and is an important cause…
  • 2013 American Transplant Congress

    Liver Transplantation (LT) in Patients Receiving Renal Replacement Therapy (RRT): Predicting Renal Recovery and Post-Transplant Futility

    V. Agopian, J. Baber, A. Dhillon, H. Petrowsky, A. Zarrinpar, F. Kaldas, H. Yersiz, D. Farmer, J. Hiatt, R. Busuttil

    Surgery, UCLA, LA, CA; Anesthesiology, UCLA, LA, CA

    Background: The Model for End-Stage Liver Disease (MELD) system prioritizes liver allocation to patients in renal failure, increasing the number of simultaneous liver-kidney transplants (SLK).…
  • 2013 American Transplant Congress

    Renal Transplant Recipients with Positive Donor Specific Antibodies Maintain Stable Graft Function with Mycophenolic Acid Escalation

    L. Rebellato, P. Bolin, K. Parker, A. Allsbrook, B. Brown, S. Kendrick, M. Everly, P. Terasaki, R. Harland

    Pathology and Laboratory Medicine, East Carolina University, Greenville, NC; Internal Medicine, East Carolina University, Greenville, NC; Eastern Nephrology Associates, Greenville, NC; Surgical Immunology and Transplantation, East Carolina University, Greenville, NC; Terasaki Foundation, Los Angeles, CA

    Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. IgG3 DSA has been associated with poorer…
  • 2013 American Transplant Congress

    How Should We Allocate Pediatric Deceased Donor Kidneys?

    W. Parker, C. Chesley, L. Ross, J. Thistlethwaite, Jr

    University of Chicago, Chicago, IL

    Background: Pediatric deceased donor kidneys (DDK) are an important source of organs for kidney transplantation although there is no consensus about 1) which candidates are…
  • 2013 American Transplant Congress

    Effect of Goal Tacrolimus Levels on Renal Function over Five Years Post-Transplant

    J. Teuteberg, A. Scanlon, S. Weaver, R. Zomak, R. Kormos, C. Bermudez, D. McNamara, M. Shullo

    Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA; Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA

    Purpose: The adverse effect of tacrolimus on renal function is well documented and lower goal levels are presumed to lead to superior renal outcomes. However…
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