2013 American Transplant Congress
MELD Trajectory Prior to Death on the Liver Waitlist
Johns Hopkins School of Medicine, Baltimore, MD
The trajectory of the MELD score prior to death in patients who die on the liver transplant waitlist has not previously been explored. Better understanding…2013 American Transplant Congress
Impact of Immunosuppression Maintenance after Failed Kidney Transplant on Panel Reactive Antibody (PRA) for Retransplantation, a Single Center Experience
Hume-Lee Transplant Center, VCUHS, Richmond, VA
Background: Most patients who failed kidney transplant become sensitized. It is uncertain whether maintaining immunosuppression with or without nephrectomy after the allograft failure will prevent…2013 American Transplant Congress
Rates of False Flagging Due to Statistical Artifact in CMS Evaluations of Transplant Programs
Surgery, Johns Hopkins School of Medicine, Baltimore, MD
The Center for Medicare/Medicaid Services (CMS) evaluates transplant centers based on risk-adjusted models produced by the Scientific Registry for Transplant Recipients (SRTR). The accuracy of…2013 American Transplant Congress
Second Role of Donor MHC Class I: Prevention of Microcirculation Injury and Alternative Macrophage Activation, The
University of Alberta, Edmonton, Canada
We previously showed that IFNG is necessary to stabilize mouse kidney allografts during T cell-mediated rejection (TCMR): lack of IFNG, IFNG receptors, or the class…2013 American Transplant Congress
Use of Sirolimus in Maintenance Immunosuppression Following Pancreas Transplantation Improves the Pancreas Graft Survival
Maintenance immunosuppressive (IS) regimens after pancreas transplantation (Tx) continue to evolve. The high immunogenic potential of the pancreas usually requires high-dose administration of calcineurin inhibitors…2013 American Transplant Congress
Predictive Value of HLA Antibody Characteristics for Progression of Subclinical Antibody Mediated Rejection in Heart Transplant Recipients
Cleveland Clinic, Cleveland, OH; The Ohio State University, Columbus, OH
Concomitant C4d and C3d detection in heart biopsies correlates with circulating DSA and graft dysfunction. Detection of C4d only in surveillance biopsies is not associated…2013 American Transplant Congress
Comparison of Voclosporin and Tacrolimus 1 Year Outcomes as Predicted by PKPD in the PROMISE Trial, A
Objective:To determine the PKPD of VCS, a new calcineurin inhibitor (CNi), compared to TAC in renal allograft patients and to explore PKPD parameters as predictors…2013 American Transplant Congress
Defect in the Th17 Pathway Worsens Renal Interstitial Fibrosis and Tubular Atrophy after Ischemic Acute Kidney Injury
Background: Ischemic acute kidney injury (AKI), which is inherent to kidney transplantation, is associated with the detrimental development of interstitial fibrosis/tubular atrophy (IF/TA). IL-17A, the…2013 American Transplant Congress
Excellent Outcomes with Transplantation of Kidneys (KTx) from Deceased Donors (DDs) with Acute Kidney Injury (AKI)
Background:AKI is common among DDs and results in high discard rates. In contrast, we have consistently used kidneys from DDs with AKI. We studied our…2013 American Transplant Congress
Quantitative Relationship of Luminex Single Antigen Bead Assay (LSA), Antibody Titration and Flow Crossmatch in Heart Transplantation – A Data Analysis of 5 Years Clinical Testing
Clinical Transplantation Immunology Lab, Duke University Medical Center, Durham, NC
Donor selecting avoiding unacceptable HLA antigens (UAs) efficiently facilities heart transplant without performing a final flow crossmatch (FCXM) prior to transplant. Luminex single antigen bead…
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